Terabyte-scale supervised 3D training and benchmarking dataset of the mouse kidney by Willy Kuo, Diego Rossinelli, Georg Schulz, Roland H. Wenger, Simone Hieber, Bert Müller, Vartan Kurtcuoglu

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The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation. by Philippe A Hasgall, David Hoogewijs, Marius B Faza, Vikram G Panse, Roland H Wenger, Gieri Camenisch

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Tumor cell endogenous HIF-1α activity induces aberrant angiogenesis and interacts with TRAF6 pathway required for colorectal cancer development by Jesus F. Glaus Garzon, Chiara Pastrello, Igor Jurisica, Michael O. Hottiger, Roland H. Wenger, Lubor Borsig

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Heritability and association with distinct genetic loci of erythropoietin levels in the general population by Tanguy Corre, Belen Ponte, Edward Pivin, Menno Pruijm, Daniel Ackermann, Georg Ehret, Katharina Spanaus, Murielle Bochud, Roland H. Wenger

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The HIFα-Stabilizing Drug Roxadustat Increases the Number of Renal Epo-Producing Sca-1⁺ Cells by Aline Jatho, Anke Zieseniss, Katja Brechtel-Curth, Jia Guo, Kai Oliver Böker, Gabriela Salinas, Roland H. Wenger, Dörthe M. Katschinski

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Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1 by Christina Pickel, Julia Günter, Amalia Ruiz-Serrano, Patrick Spielmann, Jacqueline-Alba Fabrizio, Witold Wolski, Daniel J. Peet, Roland H. Wenger, Carsten C. Scholz

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γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo. by Anu Sharma, Beata Bode, Roland H Wenger, Kuno Lehmann, Alessandro A Sartori, Holger Moch, Alexander Knuth, Lotta von Boehmer, Maries van den Broek

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Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression by Ilaria M.C. Orlando, Véronique N. Lafleur, Federica Storti, Patrick Spielmann, Lisa Crowther, Sara Santambrogio, Johannes Schödel, David Hoogewijs, David R. Mole, Roland H. Wenger

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A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression by Federica Storti, Sara Santambrogio, Lisa M. Crowther, Teresa Otto, Irene Abreu-Rodríguez, Muriel Kaufmann, Cheng-Jun Hu, Christof Dame, Joachim Fandrey, Roland H. Wenger, David Hoogewijs

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TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma by Christopher J. Mariani, Aparna Vasanthakumar, Jozef Madzo, Ali Yesilkanal, Tushar Bhagat, Yiting Yu, Sanchari Bhattacharyya, Roland H. Wenger, Susan L. Cohn, Jayasri Nanduri, Amit Verma, Nanduri R. Prabhakar, Lucy A. Godley

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Congenital erythrocytosis associated with gain-of-function HIF2A gene mutations and erythropoietin levels in the normal range by Silverio Perrotta, Daniel P. Stiehl, Francesca Punzo, Saverio Scianguetta, Adriana Borriello, Debora Bencivenga, Maddalena Casale, Bruno Nobili, Silvia Fasoli, Adriana Balduzzi, Lilla Cro, Katarzyna J. Nytko, Roland H. Wenger, Fulvio Della Ragione

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Intrinsic TGF-β signaling attenuates proximal tubule mitochondrial injury and inflammation in chronic kidney disease by Merve Kayhan, Judith Vouillamoz, Daymé Gonzalez Rodriguez, Milica Bugarski, Yasutaka Mitamura, Julia Gschwend, Christoph Schneider, Andrew Hall, David Legouis, Cezmi A. Akdis, Leary Peter, Hubert Rehrauer, Leslie Gewin, Roland H. Wenger, Stellor Nlandu Khodo

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Androglobin, a chimeric mammalian globin, is required for male fertility by Anna Keppner, Miguel Correia, Sara Santambrogio, Teng Wei Koay, Darko Maric, Carina Osterhof, Denise V Winter, Angèle Clerc, Michael Stumpe, Frédéric Chalmel, Sylvia Dewilde, Alex Odermatt, Dieter Kressler, Thomas Hankeln, Roland H Wenger, David Hoogewijs

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Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation by Jesus Cosin-Roger, Simona Simmen, Hassan Melhem, Kirstin Atrott, Isabelle Frey-Wagner, Martin Hausmann, Cheryl de Vallière, Marianne R. Spalinger, Patrick Spielmann, Roland H. Wenger, Jonas Zeitz, Stephan R. Vavricka, Gerhard Rogler, Pedro A. Ruiz

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Hypoxia Reduces the Transcription of Fibrotic Markers in the Intestinal Mucosa by Simona Simmen, Max Maane, Sarah Rogler, Katherina Baebler, Silvia Lang, Jesus Cosin-Roger, Kirstin Atrott, Isabelle Frey-Wagner, Partick Spielmann, Roland H. Wenger, Bruce Weder, Jonas Zeitz, Stephan R. Vavricka, Gerhard Rogler, Cheryl de Vallière, Martin Hausmann, Pedro A. Ruiz

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FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1. by Carsten C Scholz, Javier Rodriguez, Christina Pickel, Stephen Burr, Jacqueline-Alba Fabrizio, Karen A Nolan, Patrick Spielmann, Miguel A S Cavadas, Bianca Crifo, Doug N Halligan, James A Nathan, Daniel J Peet, Roland H Wenger, Alex Von Kriegsheim, Eoin P Cummins, Cormac T Taylor

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Identification and Functional Characterization of pVHL-Dependent Cell Surface Proteins in Renal Cell Carcinoma by Gunther Boysen, Damaris Bausch-Fluck, Claudio R. Thoma, Anna M. Nowicka, Daniel P. Stiehl, Igor Cima, Van-Duc Luu, Adriana von Teichman, Thomas Hermanns, Tullio Sulser, Barbara Ingold-Heppner, Niklaus Fankhauser, Roland H. Wenger, Wilhelm Krek, Peter Krek, Bernd Wollscheid, Holger Moch

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Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia by Charline Ladroue, David Hoogewijs, Sophie Gad, Romain Carcenac, Federica Storti, Michel Barrois, Anne-Paule Gimenez-Roqueplo, Michel Leporrier, Nicole Casadevall, Olivier Hermine, Jean-Jacques Kiladjian, André Baruchel, Fadi Fakhoury, Brigitte Bressac-de Paillerets, Jean Feunteun, Nathalie Mazure, Jacques Pouysségur, Roland H. Wenger, Stéphane Richard, Betty Gardie

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