Adoption of Machine Learning in Pharmacometrics: An Overview of Recent Implementations and Their Considerations by Alexander Janssen, Frank C. Bennis, Ron A. A. Mathôt

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Target site antibiotic concentrations in orthopedic/trauma extremity surgery: is prophylactic cefazolin adequately dosed? A systematic review and meta-analysis by Fay R K Sanders, J Carel Goslings, Ron A A Mathôt, Tim Schepers

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Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling by Alexander Janssen, Mark Hoogendoorn, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT Study Group and SYMPHONY Consortium

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Transcapillary escape rate of 125I-albumin in relation to timing of blood sampling: the need for standardization by Youssef Chahid, Nienke M. G. Rorije, Soufian el Boujoufi, Ron A. A. Mathôt, Liffert Vogt, Hein J. Verberne

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Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab by Sandor Schokker, Fabrizia Fusetti, Francesco Bonardi, Remco J. Molenaar, Ron A.A. Mathôt, Hanneke W.M. van Laarhoven

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Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study by Jeannet C. Bos, Mabor C. Mistício, Ginto Nunguiane, Ron A. A. Mathôt, Reinier M. van Hest, Jan M. Prins

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Deep compartment models: A deep learning approach for the reliable prediction of time‐series data in pharmacokinetic modeling by Alexander Janssen, Frank W. G. Leebeek, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium

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Relationship between factor VIII levels and bleeding for rFVIII‐SingleChain in severe hemophilia A: A repeated time‐to‐event analysis by Laura H. Bukkems, Siv Jönsson, Marjon H. Cnossen, Mats O. Karlsson, Ron A. A. Mathôt, the OPTI‐CLOT studies and the SYMPHONY consortium

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Pharmacokinetic/Pharmacodynamic Target Attainment of Ceftazidime in Adult Patients on General Wards with Different Degrees of Renal Function: A Prospective Observational Bicenter C... by Saskia E. Zieck, Suzanne L. de Vroom, Frouke Ph. Mulder, Gitte van Twillert, Ron A. A. Mathôt, Suzanne E. Geerlings, Reinier M. van Hest

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Population Pharmacokinetics and Probability of Target Attainment of Different Dosing Regimens of Ceftazidime in Critically Ill Patients with a Proven or Suspected <i>Pseudomonas ae... by Annabel Werumeus Buning, Caspar J. Hodiamont, Natalia M. Lechner, Margriet Schokkin, Paul W. G. Elbers, Nicole P. Juffermans, Ron A. A. Mathôt, Menno D. de Jong, Reinier M. van Hest

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Benzylpenicillin concentrations in umbilical cord blood and plasma of premature neonates following intrapartum doses for group B streptococcal prophylaxis by Amadou Samb, Thomas H. Dierikx, Yuma A. Bijleveld, Timo R. de Haan, Caspar J. Hodiamont, Elisabeth van Leeuwen, Anton H. L. C. van Kaam, Ron A. A. Mathôt, Douwe H. Visser

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Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab-paclitaxel by Anne Steins, Eva A. Ebbing, Marcel C. M. Pistorius, Cynthia Waasdorp, Kausilia K. Krishnadath, Jan Paul Medema, Johanna W. Wilmink, Ron A. A. Mathôt, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven

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Wound infection following implant removal of foot, ankle, lower leg or patella; a protocol for a multicenter randomized controlled trial investigating the (cost-)effectiveness of 2... by Fay R K Sanders, Diederick Penning, Manouk Backes, Siem A Dingemans, Susan van Dieren, Anne M Eskes, J Carel Goslings, Peter Kloen, Ron A A Mathôt, Niels W L Schep, Ingrid J B Spijkerman, Tim Schepers

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Right dose, right now: bedside, real-time, data-driven, and personalised antibiotic dosing in critically ill patients with sepsis or septic shock—a two-centre randomised clinical t... by Luca F. Roggeveen, Tingjie Guo, Lucas M. Fleuren, Ronald Driessen, Patrick Thoral, Reinier M. van Hest, Ron A. A. Mathot, Eleonora L. Swart, Harm-Jan de Grooth, Bas van den Bogaard, Armand R. J. Girbes, Rob J. Bosman, Paul W. G. Elbers

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Design of a Prospective Study on Pharmacokinetic-Guided Dosing of Prophylactic Factor Replacement in Hemophilia A and B (OPTI-CLOT TARGET Study) by Tine M.H.J. Goedhart, Laura H. Bukkems, Michiel Coppens, Karin J. Fijnvandraat, Saskia E.M. Schols, Roger E.G. Schutgens, Jeroen Eikenboom, Floor C.J.I. Heubel-Moenen, Paula F. Ypma, L. Nieuwenhuizen, K. Meijer, Frank W. G. Leebeek, Ron A.A. Mathôt, Marjon H. Cnossen

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Serum drug levels and anti-drug antibodies in the context of dose tapering by interval prolongation of adalimumab, etanercept and ustekinumab in psoriasis patients: results of the... by Selma Atalay, Sophie E. Berends, Hans M. M. Groenewoud, Ron A. A. Mathot, David M. Njoo, Johannes M. Mommers, Paul M. Ossenkoppele, Marjolein I. A. Koetsier, Maartje A. Berends, Annick de Vries, Peter C. M. van de Kerkhof, Alfons A. den Broeder, Elke M. G. J. de Jong, Juul M. P. A. van den Reek

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Rapid stromal remodeling by short‐term VEGFR2 inhibition increases chemotherapy delivery in esophagogastric adenocarcinoma by Anne Steins, Remy Klaassen, Igor Jacobs, Matthias C. Schabel, Monique G. J. T. B. vanLier, Eva A. Ebbing, Stefanie J. Hectors, Sander W. Tas, Chrissta X. Maracle, Cornelis J. A. Punt, Maria Siebes, Jacques J. G. H. M. Bergman, Jan Paul Medema, Johanna W. Wilmink, Ron A. A. Mathot, Gustav J. Strijkers, Maarten F. Bijlsma, Hanneke W. M. vanLaarhoven

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A Phase II Study Demonstrates No Feasibility of Adjuvant Treatment with Six Cycles of S-1 and Oxaliplatin in Resectable Esophageal Adenocarcinoma, with ERCC1 as Biomarker for Respo... by Charlotte I. Stroes, Sandor Schokker, Remco J. Molenaar, Ron A. A. Mathôt, Maarten F. Bijlsma, Stephanie O. van der Woude, João P. Belo Pereira, Gerrit K. J. Hooijer, Rob H. A. Verhoeven, Annemieke Cats, Cecile Grootscholten, Johanna W. van Sandick, Geert-Jan Creemers, Grard A. P. Nieuwenhuijzen, Nadia Haj Mohammad, Jelle P. Ruurda, Sybren L. Meijer, Maarten C. C. M. Hulshof, Mark I. van Berge Henegouwen, Hanneke W. M. van Laarhoven

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