The Endocannabinoid System and PPARs: Focus on Their Signalling Crosstalk, Action and Transcriptional Regulation by Fabio Arturo Iannotti, Rosa Maria Vitale

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The (Poly)Pharmacology of Cannabidiol in Neurological and Neuropsychiatric Disorders: Molecular Mechanisms and Targets by Rosa Maria Vitale, Fabio Arturo Iannotti, Pietro Amodeo

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Marine Natural and Nature-Inspired Compounds Targeting Peroxisome Proliferator Activated Receptors (PPARs) by Enrico D’Aniello, Pietro Amodeo, Rosa Maria Vitale

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Editorial: “Small molecules targeting transmembrane receptors and ion channels in drug discovery” by Rosa Maria Vitale, Fabio Arturo Iannotti, Tullio Florio, Tullio Florio

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The Combined Effect of Branching and Elongation on the Bioactivity Profile of Phytocannabinoids. Part I: Thermo-TRPs by Daiana Mattoteia, Aniello Schiano Moriello, Orazio Taglialatela-Scafati, Pietro Amodeo, Luciano De Petrocellis, Giovanni Appendino, Rosa Maria Vitale, Diego Caprioglio

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Spectroscopy data of ceftriaxone-lysozyme interaction and computational studies by Paolo Ruzza, Rosa Maria Vitale, Rohanah Hussain, Alessia Montini, Claudia Honisch, Alice Pozzebon, Charlotte S. Hughes, Barbara Biondi, Pietro Amodeo, GianPietro Sechi, Giuliano Siligardi

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Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes by Sarah Mazzotta, Gabriele Carullo, Aniello Schiano Moriello, Pietro Amodeo, Vincenzo Di Marzo, Margarita Vega-Holm, Rosa Maria Vitale, Francesca Aiello, Antonella Brizzi, Luciano De Petrocellis

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Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation by Rosa Maria Vitale, Fabio Arturo Iannotti, Aniello Schiano Moriello, Lea Tunisi, Fabiana Piscitelli, Ranjev Savopoulos, Luigia Cristino, Luciano De Petrocellis, Pietro Amodeo, Roy Gray, Vincenzo Di Marzo

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In Silico Identification and Experimental Validation of (−)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator by Enrico D’Aniello, Fabio Arturo Iannotti, Lauren G. Falkenberg, Andrea Martella, Alessandra Gentile, Fabrizia De Maio, Maria Letizia Ciavatta, Margherita Gavagnin, Joshua S. Waxman, Vincenzo Di Marzo, Pietro Amodeo, Rosa Maria Vitale

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Potent Cytotoxic Analogs of Amphidinolides from the Atlantic Octocoral Stragulum bicolor by Genoveffa Nuzzo, Bruno de Araújo Gomes, Carmela Gallo, Pietro Amodeo, Clementina Sansone, Otília D. L. Pessoa, Emiliano Manzo, Rosa Maria Vitale, Adrianna Ianora, Evelyne A. Santos, Leticia V. Costa-Lotufo, Angelo Fontana

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Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites <i>N</i>-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and E... by Anne-Sophie Archambault, Francesco Tinto, Élizabeth Dumais, Volatiana Rakotoarivelo, Magdalena Kostrzewa, Pier-Luc Plante, Cyril Martin, Mélissa Simard, Cristoforo Silvestri, Roxane Pouliot, Michel Laviolette, Louis-Philippe Boulet, Rosa Maria Vitale, Alessia Ligresti, Vincenzo Di Marzo, Nicolas Flamand

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2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors by Serena Boccella, Francesca Guida, Monica Iannotta, Fabio Arturo Iannotti, Rosmara Infantino, Flavia Ricciardi, Claudia Cristiano, Rosa Maria Vitale, Pietro Amodeo, Ida Marabese, Carmela Belardo, Vito de Novellis, Salvatore Paino, Enza Palazzo, Antonio Calignano, Vincenzo Di Marzo, Sabatino Maione, Livio Luongo

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Beneficial Effects of <i>Akkermansia muciniphila</i> Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels... by Clara Depommier, Rosa Maria Vitale, Fabio Arturo Iannotti, Cristoforo Silvestri, Nicolas Flamand, Céline Druart, Amandine Everard, Rudy Pelicaen, Dominique Maiter, Jean-Paul Thissen, Audrey Loumaye, Michel P. Hermans, Nathalie M. Delzenne, Willem M. de Vos, Vincenzo Di Marzo, Patrice D. Cani

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N-palmitoyl-D-glucosamine, A Natural Monosaccharide-Based Glycolipid, Inhibits TLR4 and Prevents LPS-Induced Inflammation and Neuropathic Pain in Mice by Monica Iannotta, Carmela Belardo, Maria Consiglia Trotta, Fabio Arturo Iannotti, Rosa Maria Vitale, Rosa Maisto, Serena Boccella, Rosmara Infantino, Flavia Ricciardi, Benito Fabio Mirto, Franca Ferraraccio, Iacopo Panarese, Pietro Amodeo, Lea Tunisi, Luigia Cristino, Michele D’Amico, Vincenzo di Marzo, Livio Luongo, Sabatino Maione, Francesca Guida

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Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest by Rosa Maria Vitale, Enrico D'Aniello, Stefania Gorbi, Andrea Martella, Cristoforo Silvestri, Maria Elisa Giuliani, Tariq Fellous, Alessandra Gentile, Marianna Carbone, Adele Cutignano, Laura Grauso, Laura Magliozzi, Gianluca Polese, Biagio D'Aniello, Fanny Defranoux, Serena Felline, Antonio Terlizzi, Antonio Calignano, Francesco Regoli, Vincenzo Di Marzo, Pietro Amodeo, Ernesto Mollo

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