The hematopoietic saga of clonality in sickle cell disease by Aaron J. Stonestrom, Ross L. Levine

Get full text

The CXCR1/CXCR2 Inhibitor Reparixin Alters the Development of Myelofibrosis in the Gata1low Mice by Paola Verachi, Francesca Gobbo, Francesca Gobbo, Fabrizio Martelli, Andrea Martinelli, Giuseppe Sarli, Andrew Dunbar, Andrew Dunbar, Ross L. Levine, Ross L. Levine, Ross L. Levine, Ronald Hoffman, Maria Teresa Massucci, Laura Brandolini, Cristina Giorgio, Marcello Allegretti, Anna Rita Migliaccio, Anna Rita Migliaccio

Get full text

Targeting mutations in cancer by Michael R. Waarts, Aaron J. Stonestrom, Young C. Park, Ross L. Levine

Get full text

Development of a customizable mouse backbone spectral flow cytometry panel to delineate immune cell populations in normal and tumor tissues by Ana Leda F. Longhini, Inés Fernández-Maestre, Inés Fernández-Maestre, Margaret C. Kennedy, Margaret C. Kennedy, Matthew G. Wereski, Shoron Mowla, Wenbin Xiao, Wenbin Xiao, Wenbin Xiao, Scott W. Lowe, Scott W. Lowe, Ross L. Levine, Ross L. Levine, Ross L. Levine, Rui Gardner

Get full text

A mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis. by Yu-Kang Cheng, Rameen Beroukhim, Ross L Levine, Ingo K Mellinghoff, Eric C Holland, Franziska Michor

Get full text

Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis. by Ying Han, Lanzhu Yue, Max Wei, Xiubao Ren, Zonghong Shao, Ling Zhang, Ross L Levine, Pearlie K Epling-Burnette

Get full text

Comparative Mutational Profiling of Hematopoietic Progenitor Cells and Circulating Endothelial Cells (CECs) in Patients with Primary Myelofibrosis by Mirko Farina, Simona Bernardi, Nicola Polverelli, Mariella D’Adda, Michele Malagola, Katia Bosio, Federica Re, Camillo Almici, Andrew Dunbar, Ross L. Levine, Domenico Russo

Get full text

Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation by Ioana I. Nitulescu, Sara C. Meyer, Qiang Jeremy Wen, John D. Crispino, Madeleine E. Lemieux, Ross L. Levine, Henry E. Pelish, Matthew D. Shair

Get full text

Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis. by Serena De Vita, Rebekka K Schneider, Michael Garcia, Jenna Wood, Mathilde Gavillet, Benjamin L Ebert, Alexander Gerbaulet, Axel Roers, Ross L Levine, Ann Mullally, David A Williams

Get full text

LSD1 Inhibition Prolongs Survival in Mouse Models of MPN by Selectively Targeting the Disease Clone by Jonas S. Jutzi, Maria Kleppe, Jennifer Dias, Hans Felix Staehle, Kaitlyn Shank, Julie Teruya-Feldstein, Sudheer Madan Mohan Gambheer, Christine Dierks, Hugh Y. Rienhoff, Jr, Ross L. Levine, Heike L. Pahl

Get full text

The Polycomb Group Protein L3MBTL1 Represses a SMAD5-Mediated Hematopoietic Transcriptional Program in Human Pluripotent Stem Cells by Fabiana Perna, Ly P. Vu, Maria Themeli, Sonja Kriks, Ruben Hoya-Arias, Raya Khanin, Todd Hricik, Jorge Mansilla-Soto, Eirini P. Papapetrou, Ross L. Levine, Lorenz Studer, Michel Sadelain, Stephen D. Nimer

Get full text

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms by Manon Viaud, Omar Abdel-Wahab, Julie Gall, Stoyan Ivanov, Rodolphe Guinamard, Sophie Sore, Johanna Merlin, Marion Ayrault, Emma Guilbaud, Arnaud Jacquel, Patrick Auberger, Nan Wang, Ross L. Levine, Alan R. Tall, Laurent Yvan-Charvet

Get full text

S125: NON-GENETIC RESISTANCE TO MENIN INHIBITION IN AML IS REVERSIBLE BY PERTURBATION OF KAT6A by Florian Perner, Homa Rahnamoun, Daniela V. Wenge, Yijun Xiong, Athina Apazidis, Disha Anand, Charlie Hatton, Yanhe Wen, Shengqing Gu, X Shirley Liu, Wenbin Xiao, Sheng F. Cai, Ross L. Levine, Gerard M. Mcgeehan, Scott A. Armstrong

Get full text

DOT1L inhibitors block abnormal self-renewal induced by cohesin loss by Katelyn E. Heimbruch, Joseph B. Fisher, Cary T. Stelloh, Emily Phillips, Michael H. Reimer, Adam J. Wargolet, Alison E. Meyer, Kirthi Pulakanti, Aaron D. Viny, Jessica J. Loppnow, Ross L. Levine, John Anto Pulikkan, Nan Zhu, Sridhar Rao

Get full text

Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures by Pierre Billon, Tarun S. Nambiar, Samuel B. Hayward, Maria P. Zafra, Emma M. Schatoff, Koichi Oshima, Andrew Dunbar, Marco Breinig, Young C. Park, Han S. Ryu, Darjus F. Tschaharganeh, Ross L. Levine, Richard Baer, Adolfo Ferrando, Lukas E. Dow, Alberto Ciccia

Get full text

A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species by Hongliang Zong, Alexander Gozman, Eloisi Caldas-Lopes, Tony Taldone, Eric Sturgill, Sarah Brennan, Stefan O. Ochiana, Erica M. Gomes-DaGama, Siddhartha Sen, Anna Rodina, John Koren III, Michael W. Becker, Charles M. Rudin, Ari Melnick, Ross L. Levine, Gail J. Roboz, Stephen D. Nimer, Gabriela Chiosis, Monica L. Guzman

Get full text

Central Role of ULK1 in Type I Interferon Signaling by Diana Saleiro, Swarna Mehrotra, Barbara Kroczynska, Elspeth M. Beauchamp, Pawel Lisowski, Beata Majchrzak-Kita, Tushar D. Bhagat, Brady L. Stein, Brandon McMahon, Jessica K. Altman, Ewa M. Kosciuczuk, Darren P. Baker, Chunfa Jie, Nadereh Jafari, Craig B. Thompson, Ross L. Levine, Eleanor N. Fish, Amit K. Verma, Leonidas C. Platanias

Get full text

A precision medicine classification for treatment of acute myeloid leukemia in older patients by Alice S. Mims, Jessica Kohlschmidt, Uma Borate, James S. Blachly, Shelley Orwick, Ann-Kathrin Eisfeld, Dimitrios Papaioannou, Deedra Nicolet, Krzysztof Mrόzek, Eytan Stein, Bhavana Bhatnagar, Richard M. Stone, Jonathan E. Kolitz, Eunice S. Wang, Bayard L. Powell, Amy Burd, Ross L. Levine, Brian J. Druker, Clara D. Bloomfield, John C. Byrd

Get full text

Clonal hematopoiesis before, during, and after human spaceflight by Nuria Mencia-Trinchant, Matthew J. MacKay, Christopher Chin, Ebrahim Afshinnekoo, Jonathan Foox, Cem Meydan, Daniel Butler, Christopher Mozsary, Nicholas A. Vernice, Charlotte Darby, Michael C. Schatz, Susan M. Bailey, Ari M. Melnick, Monica L. Guzman, Kelly Bolton, Lior Z. Braunstein, Francine Garrett-Bakelman, Ross L. Levine, Duane C. Hassane, Christopher E. Mason

Get full text

Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing by Li Zhang, Ngoc-Tung Tran, Hairui Su, Rui Wang, Yuheng Lu, Haiping Tang, Sayura Aoyagi, Ailan Guo, Alireza Khodadadi-Jamayran, Dewang Zhou, Kun Qian, Todd Hricik, Jocelyn Côté, Xiaosi Han, Wenping Zhou, Suparna Laha, Omar Abdel-Wahab, Ross L Levine, Glen Raffel, Yanyan Liu, Dongquan Chen, Haitao Li, Tim Townes, Hengbin Wang, Haiteng Deng, Y George Zheng, Christina Leslie, Minkui Luo, Xinyang Zhao

Get full text