Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma by Rouven Hoefflin, Sabine Harlander, Behnaz A. Abhari, Asin Peighambari, Mojca Adlesic, Philipp Seidel, Kyra Zodel, Stefan Haug, Burulca Göcmen, Yong Li, Bernd Lahrmann, Niels Grabe, Danijela Heide, Melanie Boerries, Anna Köttgen, Mathias Heikenwalder, Ian J. Frew

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ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma by Philipp Seidel, Anne Rubarth, Kyra Zodel, Asin Peighambari, Felix Neumann, Yannick Federkiel, Hsin Huang, Rouven Hoefflin, Mojca Adlesic, Christian Witt, David J. Hoffmann, Patrick Metzger, Ralph K. Lindemann, Frank T. Zenke, Christoph Schell, Melanie Boerries, Dominik von Elverfeldt, Wilfried Reichardt, Marie Follo, Joachim Albers, Ian J. Frew

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HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice by Rouven Hoefflin, Sabine Harlander, Silvia Schäfer, Patrick Metzger, Fengshen Kuo, Désirée Schönenberger, Mojca Adlesic, Asin Peighambari, Philipp Seidel, Chia-yi Chen, Miguel Consenza-Contreras, Andreas Jud, Bernd Lahrmann, Niels Grabe, Danijela Heide, Franziska M. Uhl, Timothy A. Chan, Justus Duyster, Robert Zeiser, Christoph Schell, Mathias Heikenwalder, Oliver Schilling, A. Ari Hakimi, Melanie Boerries, Ian J. Frew

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Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity by Rouven Hoefflin, Bernd Lahrmann, Gregor Warsow, Daniel Hübschmann, Cathleen Spath, Britta Walter, Xin Chen, Luisa Hofer, Stephan Macher-Goeppinger, Yanis Tolstov, Nina Korzeniewski, Anette Duensing, Carsten Grüllich, Dirk Jäger, Sven Perner, Gita Schönberg, Joanne Nyarangi-Dix, Sanjay Isaac, Gencay Hatiboglu, Dogu Teber, Boris Hadaschik, Sascha Pahernik, Wilfried Roth, Roland Eils, Matthias Schlesner, Holger Sültmann, Markus Hohenfellner, Niels Grabe, Stefan Duensing

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Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis by Rouven Hoefflin, Adriana Lazarou, Maria Elena Hess, Meike Reiser, Julius Wehrle, Patrick Metzger, Anna Verena Frey, Heiko Becker, Konrad Aumann, Kai Berner, Martin Boeker, Nico Buettner, Christine Dierks, Jesus Duque-Afonso, Michel Eisenblaetter, Thalia Erbes, Ralph Fritsch, Isabell Xiang Ge, Anna-Lena Geißler, Markus Grabbert, Steffen Heeg, Dieter Henrik Heiland, Simone Hettmer, Gian Kayser, Alexander Keller, Anita Kleiber, Alexandra Kutilina, Leman Mehmed, Frank Meiss, Philipp Poxleitner, Justyna Rawluk, Juri Ruf, Henning Schäfer, Florian Scherer, Khalid Shoumariyeh, Andreas Tzschach, Christoph Peters, Tilman Brummer, Martin Werner, Justus Duyster, Silke Lassmann, Cornelius Miething, Melanie Boerries, Anna L. Illert, Nikolas von Bubnoff

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