Targeting the undruggable oncogenic KRAS: the dawn of hope by Hande Asimgil, Utku Ertetik, Nedim Can Çevik, Menar Ekizce, Alper Doğruöz, Muazzez Gökalp, Elif Arık-Sever, Rouzanna Istvanffy, Helmut Friess, Güralp Onur Ceyhan, Ihsan Ekin Demir

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Protocol for whole-mount immunofluorescence staining of ECM gel-embedded innervated pancreatic organoids by Hüseyin Erdinç Beşikcioğlu, Ümmügülsüm Yurteri, Linhan Ye, Fang Zhang, Alessandra Moretti, Ibrahim Halil Gürcinar, Alper Dogruöz, Didem Karakas, Helmut Friess, Guralp Onur Ceyhan, Rouzanna Istvanffy, Ihsan Ekin Demir

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Cathepsin K maintains the compartment of bone marrow T lymphocytes in vivo by Renate Hausinger, Marianne Hackl, Ana Jardon Alvarez, Miriam Kehr, Sandra Romero Marquez, Franziska Hettler, Christian Kehr, Sandra Grziwok, Christina Schreck, Christian Peschel, Rouzanna Istvánffy, Robert A. J. Oostendorp

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Secreted factors from mouse embryonic fibroblasts maintain repopulating function of single cultured hematopoietic stem cells by Sandra Romero Marquez, Franziska Hettler, Renate Hausinger, Christina Schreck, Theresa Landspersky, Lynette Henkel, Corinne Angerpointner, Ihsan E. Demir, Matthias Schiemann, Florian Bassermann, Katharina S. Götze, Rouzanna Istvánffy, Robert A.J. Oostendorp

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Stroma-Derived Connective Tissue Growth Factor Maintains Cell Cycle Progression and Repopulation Activity of Hematopoietic Stem Cells In Vitro by Rouzanna Istvánffy, Baiba Vilne, Christina Schreck, Franziska Ruf, Charlotta Pagel, Sandra Grziwok, Lynette Henkel, Olivia Prazeres da Costa, Johannes Berndt, Volker Stümpflen, Katharina S. Götze, Matthias Schiemann, Christian Peschel, Hans-Werner Mewes, Robert A.J. Oostendorp

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Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300 by Franziska Hettler, Christina Schreck, Sandra Romero Marquez, Thomas Engleitner, Baiba Vilne, Theresa Landspersky, Heike Weidner, Renate Hausinger, Ritu Mishra, Rupert Oellinger, Martina Rauner, Ronald Naumann, Christian Peschel, Florian Bassermann, Roland Rad, Rouzanna Istvanffy, Robert A.J. Oostendorp

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Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation by Paulo L. Pfitzinger, Laura Fangmann, Kun Wang, Elke Demir, Engin Gürlevik, Bettina Fleischmann-Mundt, Jennifer Brooks, Jan G. D’Haese, Steffen Teller, Andreas Hecker, Moritz Jesinghaus, Carsten Jäger, Lei Ren, Rouzanna Istvanffy, Florian Kühnel, Helmut Friess, Güralp Onur Ceyhan, Ihsan Ekin Demir

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Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models of pancreatic cancer dictate the sensitivity to immunotherapy by Okan Safak, Shenghan Wang, Carmen Mota Reyes, Ibrahim Halil Gürcinar, Sergey Tokalov, Nedim Can Cevik, Kivanc Görgülü, Bengi Su Yilmaz, Emre Erdogan, Linhan Ye, Qiaolin Li, Elif Arik Sever, Samed Özer, Güldal Süyen, Helmut Friess, Güralp Onur Ceyhan, Rouzanna Istvanffy, Hana Algül, Ihsan Ekin Demir

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Correlation of intratumoral mast cell quantity with psychosocial distress in patients with pancreatic cancer: the PancStress study by Alicia Sitte, Ruediger Goess, Tutku Tüfekçi, Ilaria Pergolini, Paulo Leonardo Pfitzinger, Eloísa Salvo-Romero, Carmen Mota Reyes, Sergey Tokalov, Okan Safak, Hendrik Steenfadt, Ibrahim H. Gürcinar, Ümmügülsüm Yurteri, Miriam Goebel-Stengel, Gemma Mazzuoli-Weber, Andreas Stengel, Mert Erkan, Helmut Friess, Rouzanna Istvanffy, Güralp Onur Ceyhan, Elke Demir, Ihsan Ekin Demir

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Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma by Markus Schick, Le Zhang, Sabine Maurer, Hans Carlo Maurer, Konstandina Isaakaidis, Lara Schneider, Upayan Patra, Kathrin Schunck, Elena Rohleder, Julia Hofstetter, Apoorva Baluapuri, Anna Katharina Scherger, Julia Slotta-Huspenina, Franziska Hettler, Julia Weber, Thomas Engleitner, Roman Maresch, Jolanta Slawska, Richard Lewis, Rouzanna Istvanffy, Stefan Habringer, Katja Steiger, Armin Baiker, Robert A. J. Oostendorp, Cornelius Miething, Hans-Peter Lenhof, Florian Bassermann, Björn Chapuy, Matthias Wirth, Elmar Wolf, Roland Rad, Stefan Müller, Ulrich Keller

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Neoadjuvant chemotherapy is associated with suppression of the B cell-centered immune landscape in pancreatic ductal adenocarcinoma by Luise Rupp, Ina Dietsche, Maximilian Kießler, Maximilian Kießler, Maximilian Kießler, Ulrich Sommer, Alexander Muckenhuber, Katja Steiger, Casper W. F. van Eijck, Casper W. F. van Eijck, Leonard Richter, Rouzanna Istvanffy, Carsten Jäger, Helmut Friess, Helmut Friess, Casper H. J. van Eijck, Casper H. J. van Eijck, Ihsan Ekin Demir, Ihsan Ekin Demir, Ihsan Ekin Demir, Ihsan Ekin Demir, Ihsan Ekin Demir, Carmen Mota Reyes, Carmen Mota Reyes, Carmen Mota Reyes, Marc Schmitz, Marc Schmitz, Marc Schmitz

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Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion by Xiaobo Wang, Rouzanna Istvanffy, Linhan Ye, Steffen Teller, Melanie Laschinger, Kalliope N. Diakopoulos, Kıvanç Görgülü, Qiaolin Li, Lei Ren, Carsten Jäger, Katja Steiger, Alexander Muckenhuber, Baiba Vilne, Kaan Çifcibaşı, Carmen Mota Reyes, Ümmügülsüm Yurteri, Maximilian Kießler, Ibrahim Halil Gürçınar, Maya Sugden, Saliha Elif Yıldızhan, Osman Uğur Sezerman, Sümeyye Çilingir, Güldal Süyen, Maximilian Reichert, Roland M. Schmid, Stefanie Bärthel, Rupert Oellinger, Achim Krüger, Roland Rad, Dieter Saur, Hana Algül, Helmut Friess, Marina Lesina, Güralp Onur Ceyhan, Ihsan Ekin Demir

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