Two hits revisited again. অনুযায়ী Tomlinson, I, Roylance, R, Houlston, R

Loss of heterozygosity analysis: practically and conceptually flawed? অনুযায়ী Tomlinson, I, Lambros, M, Roylance, R

Allelic imbalance analysis of chromosome 16q shows that grade I and grade III invasive ductal breast cancers follow different genetic pathways. অনুযায়ী Roylance, R, Gorman, P, Hanby, A, Tomlinson, I

Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. অনুযায়ী Droufakou, S, Deshmane, V, Roylance, R, Hanby, A, Tomlinson, I, Hart, I

CDH1 and genetic predisposition to lobular breast carcinoma অনুযায়ী Petridis, C, Shinomiya, I, Simpson, M, Tomlinson, I, Roylance, R, Sawyer, E

The role of E-cadherin in low-grade ductal breast tumourigenesis. অনুযায়ী Roylance, R, Droufakou, S, Gorman, P, Gillett, C, Hart, I, Hanby, A, Tomlinson, I

Analysis of ovarian cancer cell lines using array-based comparative genomic hybridization. অনুযায়ী Lambros, M, Fiegler, H, Jones, A, Gorman, P, Roylance, R, Carter, N, Tomlinson, I

Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma. অনুযায়ী Jones, A, Douglas, E, Halford, SE, Fiegler, H, Gorman, P, Roylance, R, Carter, N, Tomlinson, I

Genetic analysis of lobular carcinoma in situ and associated invasive lobular cancer অনুযায়ী Yates, L, Jones, A, Patel, H, Mackay, A, Gillett, C, Pinder, S, Tomlinson, I, Roylance, R, Sawyer, E

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway অনুযায়ী Woodford-Richens, K, Rowan, A, Gorman, P, Halford, S, Bicknell, D, Wasan, H, Roylance, R, Bodmer, W, Tomlinson, I

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. অনুযায়ী Woodford-Richens, K, Rowan, A, Gorman, P, Halford, S, Bicknell, D, Wasan, H, Roylance, R, Bodmer, W, Tomlinson, I

Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability. অনুযায়ী Alam, N, Gorman, P, Jaeger, E, Kelsell, D, Leigh, I, Ratnavel, R, Murdoch, M, Houlston, R, Aaltonen, L, Roylance, R, Tomlinson, I

APC and the three-hit hypothesis. অনুযায়ী Segditsas, S, Rowan, A, Howarth, K, Jones, A, Leedham, S, Wright, N, Gorman, P, Chambers, W, Domingo, E, Roylance, R, Sawyer, E, Sieber, O, Tomlinson, I

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC. অনুযায়ী Sieber, O, Heinimann, K, Gorman, P, Lamlum, H, Crabtree, M, Simpson, C, Davies, D, Neale, K, Hodgson, S, Roylance, R, Phillips, R, Bodmer, W, Tomlinson, I

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instab... অনুযায়ী Gaasenbeek, M, Howarth, K, Rowan, A, Gorman, P, Jones, A, Chaplin, T, Liu, Y, Bicknell, D, Davison, E, Fiegler, H, Carter, N, Roylance, R, Tomlinson, I

Germline CDH1 mutations in bilateral lobular carcinoma in situ. অনুযায়ী Petridis, C, Shinomiya, I, Kohut, K, Gorman, P, Caneppele, M, Shah, V, Troy, M, Pinder, SE, Hanby, A, Tomlinson, I, Trembath, R, Roylance, R, Simpson, M, Sawyer, E

Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer অনুযায়ী Roylance, R, Endesfelder, D, Gorman, P, Burrell, R, Sander, J, Tomlinson, I, Hanby, A, Speirs, V, Richardson, A, Birkbak, N, Eklund, A, Downward, J, Kschischo, M, Szallasi, Z, Swanton, C

Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer. অনুযায়ী Roylance, R, Endesfelder, D, Gorman, P, Burrell, R, Sander, J, Tomlinson, I, Hanby, A, Speirs, V, Richardson, A, Birkbak, N, Eklund, A, Downward, J, Kschischo, M, Szallasi, Z, Swanton, C

A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH. অনুযায়ী Roylance, R, Gorman, P, Papior, T, Wan, Y, Ives, M, Watson, J, Collins, C, Wortham, N, Langford, C, Fiegler, H, Carter, N, Gillett, C, Sasieni, P, Pinder, S, Hanby, A, Tomlinson, I

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis. অনুযায়ী Lamlum, H, Ilyas, M, Rowan, A, Clark, S, Johnson, V, Bell, J, Frayling, I, Efstathiou, J, Pack, K, Payne, S, Roylance, R, Gorman, P, Sheer, D, Neale, K, Phillips, R, Talbot, I, Bodmer, W, Tomlinson, I