Complement in Metastasis: A Comp in the Camp by Daniel Ajona, Daniel Ajona, Daniel Ajona, Daniel Ajona, Sergio Ortiz-Espinosa, Sergio Ortiz-Espinosa, Ruben Pio, Ruben Pio, Ruben Pio, Ruben Pio, Fernando Lecanda, Fernando Lecanda, Fernando Lecanda, Fernando Lecanda

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Complementing the Cancer-Immunity Cycle by Ruben Pio, Ruben Pio, Ruben Pio, Daniel Ajona, Daniel Ajona, Daniel Ajona, Sergio Ortiz-Espinosa, Alberto Mantovani, Alberto Mantovani, John D. Lambris

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C5a elevation in convalescents from severe COVID-19 is not associated with early complement activation markers C3bBbP or C4d by Daria Kowalska, Alicja Kuźniewska, Yaiza Senent, Yaiza Senent, Yaiza Senent, Beatriz Tavira, Beatriz Tavira, Beatriz Tavira, Susana Inogés, Susana Inogés, Susana Inogés, Ascensión López-Díaz de Cerio, Ascensión López-Díaz de Cerio, Ascensión López-Díaz de Cerio, Ruben Pio, Ruben Pio, Ruben Pio, Ruben Pio, Marcin Okrój, José Ramón Yuste, José Ramón Yuste, José Ramón Yuste

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Editorial: The Role of Complement in Tumors by Barbara E. Rolfe, Ruben Pio, Trent M. Woodruff, Maciej M. Markiewski, Helga D. Manthey

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Contrasting responses of non‐small cell lung cancer to antiangiogenic therapies depend on histological subtype by Marta Larrayoz, Ruben Pio, María J Pajares, Isabel Zudaire, Daniel Ajona, Oriol Casanovas, Luis M Montuenga, Jackeline Agorreta

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Persistence of High Levels of Serum Complement C5a in Severe COVID-19 Cases After Hospital Discharge by Yaiza Senent, Yaiza Senent, Yaiza Senent, Susana Inogés, Susana Inogés, Susana Inogés, Ascensión López-Díaz de Cerio, Ascensión López-Díaz de Cerio, Ascensión López-Díaz de Cerio, Andres Blanco, Arantxa Campo, Francisco Carmona-Torre, Francisco Carmona-Torre, Francisco Carmona-Torre, Patricia Sunsundegui, Antonio González-Martín, Antonio González-Martín, Daniel Ajona, Daniel Ajona, Daniel Ajona, Daniel Ajona, Marcin Okrój, Felipe Prósper, Felipe Prósper, Felipe Prósper, Felipe Prósper, Ruben Pio, Ruben Pio, Ruben Pio, Ruben Pio, José Ramón Yuste, José Ramón Yuste, José Ramón Yuste, Beatriz Tavira, Beatriz Tavira, Beatriz Tavira

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Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer. by Iñaki Valles, Maria J Pajares, Victor Segura, Elisabet Guruceaga, Javier Gomez-Roman, David Blanco, Akiko Tamura, Luis M Montuenga, Ruben Pio

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Silica-induced Chronic Inflammation Promotes Lung Carcinogenesis in the Context of an Immunosuppressive Microenvironment by Javier Freire, Daniel Ajona, Gabriel de Biurrun, Jackeline Agorreta, Victor Segura, Elizabeth Guruceaga, Anne-Marie Bleau, Ruben Pio, David Blanco, Luis M Montuenga

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Expression of sirtuin 1 and 2 is associated with poor prognosis in non-small cell lung cancer patients. by Ivana Grbesa, María J Pajares, Elena Martínez-Terroba, Jackeline Agorreta, Ana-Matea Mikecin, Marta Larráyoz, Miguel A Idoate, Koraljka Gall-Troselj, Ruben Pio, Luis M Montuenga

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Molecular Analysis of a Multistep Lung Cancer Model Induced by Chronic Inflammation Reveals Epigenetic Regulation of p16, Activation of the DNA Damage Response Pathway by David Blanco, Silvestre Vicent, Mario F. Fraga, Ignacio Fernandez-Garcia, Javier Freire, Amaia Lujambio, Manel Esteller, Carlos Ortiz-de-Solorzano, Ruben Pio, Fernando Lecanda, Luis M. Montuenga

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Comparison of RNA-seq and microarray platforms for splice event detection using a cross-platform algorithm by Juan P. Romero, María Ortiz-Estévez, Ander Muniategui, Soraya Carrancio, Fernando J. de Miguel, Fernando Carazo, Luis M. Montuenga, Remco Loos, Rubén Pío, Matthew W. B. Trotter, Angel Rubio

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Elevated levels of the complement activation product C4d in bronchial fluids for the diagnosis of lung cancer. by Daniel Ajona, Cristina Razquin, Maria Dolores Pastor, Maria Jose Pajares, Javier Garcia, Felipe Cardenal, Michael Fleischhacker, Maria Dolores Lozano, Javier J Zulueta, Bernd Schmidt, Ernest Nadal, Luis Paz-Ares, Luis M Montuenga, Ruben Pio

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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation by Ander Puyalto, María Rodríguez-Remírez, Inés López, Irati Macaya, Elizabeth Guruceaga, María Olmedo, Anna Vilalta-Lacarra, Connor Welch, Sergio Sandiego, Silvestre Vicent, Karmele Valencia, Alfonso Calvo, Ruben Pio, Luis E. Raez, Christian Rolfo, Daniel Ajona, Ignacio Gil-Bazo

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Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood by Alejandro Rodríguez‐Pena, Estibaliz Armendariz, Alvaro Oyarbide, Xabier Morales, Sergio Ortiz‐Espinosa, Borja Ruiz‐Fernández de Córdoba, Denis Cochonneau, Iñaki Cornago, Dominique Heymann, Josepmaría Argemi, Delia D'Avola, Bruno Sangro, Fernando Lecanda, Ruben Pio, Iván Cortés‐Domínguez, Carlos Ortiz‐de‐Solórzano

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SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation by Jackeline Agorreta, Ana Remirez, Ruben Pio, Luis M Montuenga, Teresa Lozano, Esther Redin, Irati Garmendia, Diego Serrano, Yaiza Senent, Miriam Redrado, Maria Villalba, Francisco Exposito, Daniel Ajona, Sergio Ortiz-Espinosa, Cristina Bertolo, Cristina Sainz, Juana Garcia-Pedrero, Juan Lasarte, Alfonso Calvo

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G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1 by Francisco Exposito, Miriam Redrado, Diego Serrano, Silvia Calabuig-Fariñas, Aida Bao-Caamano, Sandra Gallach, Eloisa Jantus-Lewintre, Angel Diaz-Lagares, Aitor Rodriguez-Casanova, Juan Sandoval, Edurne San Jose-Eneriz, Javier Garcia, Esther Redin, Yaiza Senent, Sergio Leon, Ruben Pio, Rafael Lopez, Julen Oyarzabal, Antonio Pineda-Lucena, Xabier Agirre, Luis M. Montuenga, Felipe Prosper, Alfonso Calvo

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Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarc... by Ana Patiño-García, Elizabeth Guruceaga, Maria Pilar Andueza, Marimar Ocón, Jafait Junior Fodop Sokoudjou, Nicolás de Villalonga Zornoza, Gorka Alkorta-Aranburu, Ibon Tamayo Uria, Alfonso Gurpide, Carlos Camps, Eloísa Jantus-Lewintre, Maria Navamuel-Andueza, Miguel F. Sanmamed, Ignacio Melero, Mohamed Elgendy, Juan Pablo Fusco, Javier J. Zulueta, Juan P. de-Torres, Gorka Bastarrika, Luis Seijo, Ruben Pio, Luis M. Montuenga, Mikel Hernáez, Idoia Ochoa, Jose Luis Perez-Gracia

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Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco‐induced lung cancer by Juan Pablo Fusco, Guillermo Pita, María José Pajares, Maria Pilar Andueza, Ana Patiño‐García, Juan P. de‐Torres, Alfonso Gurpide, Javier Zulueta, Rosario Alonso, Nuria Alvarez, Ruben Pio, Ignacio Melero, Miguel F. Sanmamed, Maria Rodriguez Ruiz, Ignacio Gil‐Bazo, Jose María Lopez‐Picazo, Ciro Casanova, Rebeca Baz Davila, Antonio Agudo, Maria Dolores Lozano, Alvaro Gonzalez, Nuria Sala, Eva Ardanaz, Javier Benitez, Luis Montuenga, Anna Gonzalez‐Neira, Jose Luis Perez‐Gracia

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