Editorial of Special Column “Natural Product Screening” by Ruin Moaddel, Zhengjin Jiang

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A Pilot Proteomic Analysis of Huntington’s Disease by Functional Capacity by Andrew McGarry, Ruin Moaddel

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Searching for a mitochondrial root to the decline in muscle function with ageing by Marta Gonzalez‐Freire, Fatemeh Adelnia, Ruin Moaddel, Luigi Ferrucci

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Metabolites Associated with Memory and Gait: A Systematic Review by Qu Tian, Brendan A. Mitchell, Abigail E. Corkum, Ruin Moaddel, Luigi Ferrucci

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Identification of gingerenone A as a novel senolytic compound. by Ruin Moaddel, Martina Rossi, Stephanie Rodriguez, Rachel Munk, Mohammed Khadeer, Kotb Abdelmohsen, Myriam Gorospe, Luigi Ferrucci

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Ketamine Metabolites Enantioselectively Decrease Intracellular D-Serine Concentrations in PC-12 Cells. by Nagendra S Singh, Ewelina Rutkowska, Anita Plazinska, Mohammed Khadeer, Ruin Moaddel, Krzysztof Jozwiak, Michel Bernier, Irving W Wainer

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Physical Activity Associated Proteomics of Skeletal Muscle: Being Physically Active in Daily Life May Protect Skeletal Muscle From Aging by Ceereena Ubaida-Mohien, Marta Gonzalez-Freire, Alexey Lyashkov, Ruin Moaddel, Chee W. Chia, Eleanor M. Simonsick, Ranjan Sen, Luigi Ferrucci

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Proteins in the pathway from high red blood cell width distribution to all-cause mortality by Yusuke Osawa, Toshiko Tanaka, Richard D. Semba, Giovanna Fantoni, Ruin Moaddel, Julián Candia, Eleanor M. Simonsick, Stefania Bandinelli, Luigi Ferrucci

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An exploratory metabolomic comparison of participants with fast or absent functional progression from 2CARE, a randomized, double-blind clinical trial in Huntington’s disease by Andrew McGarry, Krystal Hunter, John Gaughan, Peggy Auinger, Thomas N. Ferraro, Basant Pradhan, Luigi Ferrucci, Josephine M. Egan, Ruin Moaddel

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Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington’s disease for participants of varying functional disability: a pilot study by Andrew McGarry, John Gaughan, Cory Hackmyer, Jacqueline Lovett, Mohammed Khadeer, Hamza Shaikh, Basant Pradhan, Thomas N. Ferraro, Irving W. Wainer, Ruin Moaddel

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Author Correction: Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington’s disease for participants of varying functional disability: a pilot study by Andrew McGarry, John Gaughan, Cory Hackmyer, Jacqueline Lovett, Mohammed Khadeer, Hamza Shaikh, Basant Pradhan, Thomas N. Ferraro, Irving W. Wainer, Ruin Moaddel

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Human Metabolome Reference Database in a Biracial Cohort across the Adult Lifespan by Qu Tian, M. Gordian Adam, Enrique Ozcariz, Giovanna Fantoni, Nader M. Shehadeh, Lisa M. Turek, Victoria L. Collingham, Mary Kaileh, Ruin Moaddel, Luigi Ferrucci

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Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians by Ceereena Ubaida-Mohien, Sally Spendiff, Alexey Lyashkov, Ruin Moaddel, Norah J MacMillan, Marie-Eve Filion, Jose A Morais, Tanja Taivassalo, Luigi Ferrucci, Russell T Hepple

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Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria by Ceereena Ubaida-Mohien, Alexey Lyashkov, Marta Gonzalez-Freire, Ravi Tharakan, Michelle Shardell, Ruin Moaddel, Richard D Semba, Chee W Chia, Myriam Gorospe, Ranjan Sen, Luigi Ferrucci

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Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. by Wei-na Cong, Rui Wang, Huan Cai, Caitlin M Daimon, Morten Scheibye-Knudsen, Vilhelm A Bohr, Rebecca Turkin, William H Wood, Kevin G Becker, Ruin Moaddel, Stuart Maudsley, Bronwen Martin

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Serum lipids in adults with late age-related macular degeneration: a case-control study by Richard D. Semba, Ruin Moaddel, Mary Frances Cotch, Fridbert Jonasson, Gudny Eiriksdottir, Tamara B. Harris, Lenore J. Launer, Kai Sun, Ronald Klein, Debra A. Schaumberg, Pálmi Jónsson, Vilmundur Gudnason, Luigi Ferrucci

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Proteomics and Epidemiological Models of Human Aging by Ceereena Ubaida-Mohien, Ruin Moaddel, Ann Zenobia Moore, Pei-Lun Kuo, Faraz Faghri, Faraz Faghri, Faraz Faghri, Ravi Tharakan, Toshiko Tanaka, Mike A. Nalls, Mike A. Nalls, Mike A. Nalls, Luigi Ferrucci

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Kynurenines link chronic inflammation to functional decline and physical frailty by Reyhan Westbrook, Tae Chung, Jacqueline Lovett, Chris Ward, Humberto Joca, Huanle Yang, Mohammed Khadeer, Jing Tian, Qian-Li Xue, Anne Le, Luigi Ferrucci, Ruin Moaddel, Rafa de Cabo, Ahmet Hoke, Jeremy Walston, Peter M. Abadir

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Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration by Ruin Moaddel, Panos Zanos, Cristan A. Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate

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Cerebrospinal fluid exploratory proteomics and ketamine metabolite pharmacokinetics in human volunteers after ketamine infusion by Ruin Moaddel, Cristan A. Farmer, Mani Yavi, Bashkim Kadriu, Min Zhu, Jinshui Fan, Qinghua Chen, Elin Lehrmann, Giovanna Fantoni, Supriyo De, Caio H. Mazucanti, Elia E. Acevedo-Diaz, Peixiong Yuan, Todd D. Gould, Lawrence T. Park, Josephine M. Egan, Luigi Ferrucci, Carlos A. Zarate, Jr.

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