Utilizing Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Analyze Interstitial Fluid Flow and Transport in Glioblastoma and the Surrounding Parenchyma in Human Pa... by Krishnashis Chatterjee, Naciye Atay, Daniel Abler, Saloni Bhargava, Prativa Sahoo, Russell C. Rockne, Jennifer M. Munson

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Synthetic Apparent Diffusion Coefficient for High b-Value Diffusion-Weighted MRI in Prostate by Prativa Sahoo, Russell C. Rockne, Alexander Jung, Pradeep K Gupta, Ram K. S. Rathore, Rakesh K. Gupta

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Modeling interaction of Glioma cells and CAR T-cells considering multiple CAR T-cells bindings by Runpeng Li, Prativa Sahoo, Dongrui Wang, Qixuan Wang, Christine E. Brown, Russell C. Rockne, Heyrim Cho

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Structural and practical identifiability of contrast transport models for DCE-MRI. by Martina Conte, Ryan T Woodall, Margarita Gutova, Bihong T Chen, Mark S Shiroishi, Christine E Brown, Jennifer M Munson, Russell C Rockne

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Differential Distribution of Brain Metastases from Non-Small Cell Lung Cancer Based on Mutation Status by Bihong T. Chen, Taihao Jin, Ningrong Ye, Sean W. Chen, Russell C. Rockne, Stephanie Yoon, Isa Mambetsariev, Ebenezer Daniel, Ravi Salgia

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Bow-tie architectures in biological and artificial neural networks: Implications for network evolution and assay design by Seth Hilliard, Karen Mosoyan, Sergio Branciamore, Grigoriy Gogoshin, Alvin Zhang, Diana L. Simons, Russell C. Rockne, Peter P. Lee, Andrei S. Rodin

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Neuroprotective potential of intranasally delivered L-myc immortalized human neural stem cells in female rats after a controlled cortical impact injury by Mari Amirbekyan, Vikram Adhikarla, Jeffrey P. Cheng, Eleni H. Moschonas, Corina O. Bondi, Russell C. Rockne, Anthony E. Kline, Margarita Gutova

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Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables by Alexander B. Brummer, Alexander B. Brummer, Agata Xella, Ryan Woodall, Vikram Adhikarla, Heyrim Cho, Margarita Gutova, Christine E. Brown, Russell C. Rockne

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Early Changes in Tumor Perfusion from T1-Weighted Dynamic Contrast-Enhanced MRI following Neural Stem Cell-Mediated Therapy of Recurrent High-Grade Glioma Correlate with Overall Su... by Prativa Sahoo, Paul Frankel, Julie Ressler, Margarita Gutova, Alexander J. Annala, Behnam Badie, Jana Portnow, Karen S. Aboody, Massimo D’Apuzzo, Russell C. Rockne

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Intranasally Administered L-Myc-Immortalized Human Neural Stem Cells Migrate to Primary and Distal Sites of Damage after Cortical Impact and Enhance Spatial Learning by Margarita Gutova, Jeffrey P. Cheng, Vikram Adhikarla, Lusine Tsaturyan, Michael E. Barish, Russell C. Rockne, Eleni H. Moschonas, Corina O. Bondi, Anthony E. Kline

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Systems profiling reveals recurrently dysregulated cytokine signaling responses in ER+ breast cancer patients’ blood by Brian Orcutt-Jahns, Joao Rodrigues Lima Junior, Emily Lin, Russell C. Rockne, Adina Matache, Sergio Branciamore, Ethan Hung, Andrei S. Rodin, Peter P. Lee, Aaron S. Meyer

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580 Mapping interstitial fluid flow in the brain to improve CAR T cell trafficking and efficacy by Christine Brown, Renate Starr, Brenda Aguilar, Behnam Badie, Vanessa Salvary, Eric Ma, Darya Alizadeh, Russell C Rockne, Margarita Gutova, Ryan Woodall, Cora Esparza, Jennifer M Munson

Designing combination therapies for cancer treatment: application of a mathematical framework combining CAR T-cell immunotherapy and targeted radionuclide therapy by Vikram Adhikarla, Dennis Awuah, Enrico Caserta, Megan Minnix, Maxim Kuznetsov, Amrita Krishnan, Jefferey Y. C. Wong, John E. Shively, Xiuli Wang, Flavia Pichiorri, Russell C. Rockne

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Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI by Ryan T. Woodall, Cora C. Esparza, Margarita Gutova, Maosen Wang, Jessica J. Cunningham, Alexander B. Brummer, Caleb A. Stine, Christine C. Brown, Jennifer M. Munson, Russell C. Rockne

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Proteomics and mathematical modeling of longitudinal CSF differentiates fast versus slow ALS progression by Lucas Vu, Krystine Garcia‐Mansfield, Antonio Pompeiano, Jiyan An, Victoria David‐Dirgo, Ritin Sharma, Vinisha Venugopal, Harkeerat Halait, Guido Marcucci, Ya‐Huei Kuo, Lisa Uechi, Russell C. Rockne, Patrick Pirrotte, Robert Bowser

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Challenges with sirolimus experimental data to inform QSP model of post‐transplantation cyclophosphamide regimens by Ezhilpavai Mohanan, Guofang Shen, Suping Ren, Hsuan‐Hao Fan, Kao Tang Ying Moua, Aleksandra Karolak, Russell C. Rockne, Ryotaro Nakamura, David A. Horne, Christopher G. Kanakry, Donald E. Mager, Jeannine S. McCune

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1484 An interplay between innate/adaptive/humoral immunity leads to increased immunogenicity of melanoma vs. non-melanoma derived brain metastases by Kim Margolin, Ludmila Danilova, Maria L Ascierto, Russell C Rockne, Alberto Mendoza Valderrey, Daria M Kessler, Douglas A Hanes, Ethan Dettmann, Kai Rau, Yueqin Quan, Stacey Stern, Daniel F Kelly, Garni Barkhoudarian, Steven E Kolker

Pharmacological activity of OST-01, a natural product from baccharis coridifolia, on breast cancer cells by HyunJun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben Pathak, William Graff, Alexis LeVee, Jun Wu, Mark A. LaBarge, David Frankhouser, Russell C. Rockne, Patrick Pirrotte, Bin Zhang, Joanne Mortimer, Le Xuan Truong Nguyen, Guido Marcucci

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1520 Phase I trial evaluating locoregionally-delivered IL13Rα2-targeting CAR T cells in high-grade glioma by Stephen J Forman, Massimo D’Apuzzo, Renate Starr, Christine E Brown, Brenda Aguilar, Michael E Barish, Behnam Badie, Leo D Wang, Darya Alizadeh, Jonathan C Hibbard, Marie Suzette Blanchard, Heini M Natri, Dongrui Wang, Julie R Ostberg, Jamie R Wagner, Jinny A Paul, Aleksandr Filippov, Ammar Chaudhry, Julie A Ressler, Julie Kilpatrick, Paige Myers-McNamara, Mike Chen, Russell C Rockne, Joseph Georges, Jana Portnow, Nicholas E Banovich