Identification of candidate enhancers controlling the transcriptome during the formation of interphalangeal joints by Karol Nowosad, Rutger W. W. Brouwer, Adrian Odrzywolski, Anne L. Korporaal, Bartłomiej Gielniewski, Bartosz Wojtaś, Wilfred F. J. van IJcken, Frank Grosveld, Danny Huylebroeck, Przemko Tylzanowski

Get full text

Effect of bovine milk fat-based infant formulae on microbiota, metabolites and stool parameters in healthy term infants in a randomized, crossover, placebo-controlled trial by Ellen Looijesteijn, Rutger W. W. Brouwer, Ruud J. W. Schoemaker, Laurien H. Ulfman, Stephanie L. Ham, Prescilla Jeurink, Eva Karaglani, Wilfred F. J. van IJcken, Yannis Manios

Get full text

Single-Cell RNA Sequencing of Donor-Reactive T Cells Reveals Role of Apoptosis in Donor-Specific Hyporesponsiveness of Kidney Transplant Recipients by Amy C. J. van der List, Nicolle H. R. Litjens, Rutger W. W. Brouwer, Mariska Klepper, Alexander T. den Dekker, Wilfred F. J. van Ijcken, Michiel G. H. Betjes

Get full text

Comparison of Single Cell Transcriptome Sequencing Methods: Of Mice and Men by Bastian V. H. Hornung, Zakia Azmani, Alexander T. den Dekker, Edwin Oole, Zeliha Ozgur, Rutger W. W. Brouwer, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken

Get full text

Heritability and De Novo Mutations in Oesophageal Atresia and Tracheoesophageal Fistula Aetiology by Erwin Brosens, Rutger W. W. Brouwer, Hannie Douben, Yolande van Bever, Alice S. Brooks, Rene M. H. Wijnen, Wilfred F. J. van IJcken, Dick Tibboel, Robbert J. Rottier, Annelies de Klein

Get full text

Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome by Judith C. Birkhoff, Anne L. Korporaal, Rutger W. W. Brouwer, Karol Nowosad, Claudia Milazzo, Lidia Mouratidou, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Danny Huylebroeck, Andrea Conidi

Get full text

Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts by Steven Heshusius, Laura Grech, Nynke Gillemans, Rutger W. W. Brouwer, Xander T. den Dekker, Wilfred F. J. van IJcken, Benjamin Nota, Alex E. Felice, Thamar B. van Dijk, Marieke von Lindern, Joseph Borg, Emile van den Akker, Sjaak Philipsen

Get full text

Unraveling the Genetics of Congenital Diaphragmatic Hernia: An Ongoing Challenge by Erwin Brosens, Nina C. J. Peters, Kim S. van Weelden, Kim S. van Weelden, Kim S. van Weelden, Charlotte Bendixen, Rutger W. W. Brouwer, Rutger W. W. Brouwer, Frank Sleutels, Hennie T. Bruggenwirth, Wilfred F. J. van Ijcken, Wilfred F. J. van Ijcken, Danielle C. M. Veenma, Danielle C. M. Veenma, Suzan C. M. Cochius-Den Otter, Rene M. H. Wijnen, Alex J. Eggink, Marieke F. van Dooren, Heiko Martin Reutter, Heiko Martin Reutter, Robbert J. Rottier, Robbert J. Rottier, J. Marco Schnater, Dick Tibboel, Annelies de Klein

Get full text

MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome by Ilaria Parenti, Farah Diab, Sara Ruiz Gil, Eskeatnaf Mulugeta, Valentina Casa, Riccardo Berutti, Rutger W.W. Brouwer, Valerie Dupé, Juliane Eckhold, Elisabeth Graf, Beatriz Puisac, Feliciano Ramos, Thomas Schwarzmayr, Macarena Moronta Gines, Thomas van Staveren, Wilfred F.J. van IJcken, Tim M. Strom, Juan Pié, Erwan Watrin, Frank J. Kaiser, Kerstin S. Wendt

Get full text

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue by Job van Riet, Chinmoy Saha, Nikolaos Strepis, Rutger W. W. Brouwer, Elena S. Martens-Uzunova, Wesley S. van de Geer, Sigrid M. A. Swagemakers, Andrew Stubbs, Yassir Halimi, Sanne Voogd, Arif Mohammad Tanmoy, Malgorzata A. Komor, Youri Hoogstrate, Bart Janssen, Remond J. A. Fijneman, Yashar S. Niknafs, Arul M. Chinnaiyan, Wilfred F. J. van IJcken, Peter J. van der Spek, Guido Jenster, Rogier Louwen

Get full text

Exome-Wide Meta-Analysis Identifies Rare 3′-UTR Variant in ERCC1/CD3EAP Associated with Symptoms of Sleep Apnea by Ashley van der Spek, Annemarie I. Luik, Desana Kocevska, Chunyu Liu, Chunyu Liu, Chunyu Liu, Rutger W. W. Brouwer, Jeroen G. J. van Rooij, Jeroen G. J. van Rooij, Jeroen G. J. van Rooij, Mirjam C. G. N. van den Hout, Robert Kraaij, Robert Kraaij, Robert Kraaij, Albert Hofman, Albert Hofman, André G. Uitterlinden, André G. Uitterlinden, André G. Uitterlinden, Wilfred F. J. van IJcken, Daniel J. Gottlieb, Daniel J. Gottlieb, Daniel J. Gottlieb, Henning Tiemeier, Henning Tiemeier, Cornelia M. van Duijn, Najaf Amin

Get full text

Exome Sequencing Analysis Identifies Rare Variants in ATM and RPL8 That Are Associated With Shorter Telomere Length by Ashley van der Spek, Ashley van der Spek, Sophie C. Warner, Linda Broer, Christopher P. Nelson, Christopher P. Nelson, Dina Vojinovic, Shahzad Ahmad, Pascal P. Arp, Rutger W. W. Brouwer, Matthew Denniff, Mirjam C. G. N. van den Hout, Jeroen G. J. van Rooij, Jeroen G. J. van Rooij, Robert Kraaij, Wilfred F. J. van IJcken, Nilesh J. Samani, Nilesh J. Samani, M. Arfan Ikram, André G. Uitterlinden, André G. Uitterlinden, Veryan Codd, Veryan Codd, Najaf Amin, Najaf Amin, Cornelia M. van Duijn, Cornelia M. van Duijn

Get full text