Mucosal IgA Responses: Damaged in Established HIV Infection—Yet, Effective Weapon against HIV Transmission by Viraj Kulkarni, Ruth M. Ruprecht, Ruth M. Ruprecht

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Immunoglobulin M: An Ancient Antiviral Weapon – Rediscovered by Siqi Gong, Siqi Gong, Ruth M. Ruprecht, Ruth M. Ruprecht

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Cooperation Between Systemic IgG1 and Mucosal Dimeric IgA2 Monoclonal Anti-HIV Env Antibodies: Passive Immunization Protects Indian Rhesus Macaques Against Mucosal SHIV Challenges by Siqi Gong, Siqi Gong, Samir K. Lakhashe, Dinesh Hariraju, Dinesh Hariraju, Hanna Scinto, Hanna Scinto, Antonio Lanzavecchia, Antonio Lanzavecchia, Elisabetta Cameroni, Elisabetta Cameroni, Davide Corti, Davide Corti, Sarah J. Ratcliffe, Kenneth A. Rogers, Kenneth A. Rogers, Peng Xiao, Jane Fontenot, François Villinger, François Villinger, Ruth M. Ruprecht, Ruth M. Ruprecht, Ruth M. Ruprecht, Ruth M. Ruprecht

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Variations in the Biological Functions of HIV-1 Clade C Envelope in a SHIV-Infected Rhesus Macaque during Disease Progression. by For Yue Tso, Levon Abrahamyan, Shiu-Lok Hu, Ruth M Ruprecht, Charles Wood

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Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells? by Siqi Gong, Seijal Gautam, Joshua D. Coneglio, Hanna B. Scinto, Ruth M. Ruprecht

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Inducing cross-clade neutralizing antibodies against HIV-1 by immunofocusing. by Michael Humbert, Robert A Rasmussen, Helena Ong, Fabian M P Kaiser, Shiu-Lok Hu, Ruth M Ruprecht

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Dynamics of envelope evolution in clade C SHIV-infected pig-tailed macaques during disease progression analyzed by ultra-deep pyrosequencing. by For Yue Tso, Damien C Tully, Sandra Gonzalez, Christopher Quince, On Ho, Patricia Polacino, Ruth M Ruprecht, Shiu-Lok Hu, Charles Wood

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Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Chall... by Samir K. Lakhashe, Mario Amacker, Mario Amacker, Dinesh Hariraju, Dinesh Hariraju, Dinesh Hariraju, Hemant K. Vyas, Kyle S. Morrison, Joshua A. Weiner, Margaret E. Ackerman, Margaret E. Ackerman, Vicky Roy, Galit Alter, Galit Alter, Guido Ferrari, Guido Ferrari, David C. Montefiori, David C. Montefiori, Georgia D. Tomaras, Georgia D. Tomaras, Georgia D. Tomaras, Georgia D. Tomaras, Sheetal Sawant, Nicole L. Yates, Chris Gast, Sylvain Fleury, Ruth M. Ruprecht, Ruth M. Ruprecht, Ruth M. Ruprecht

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Schistosoma mansoni enhances host susceptibility to mucosal but not intravenous challenge by R5 Clade C SHIV. by Nagadenahalli B Siddappa, Girish Hemashettar, Vivekanandan Shanmuganathan, Amma A Semenya, Elizabeth D Sweeney, Katherine S Paul, Sandra J Lee, W Evan Secor, Ruth M Ruprecht

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Acute Schistosoma mansoni infection increases susceptibility to systemic SHIV clade C infection in rhesus macaques after mucosal virus exposure. by Agnès-Laurence Chenine, Ela Shai-Kobiler, Lisa N Steele, Helena Ong, Peter Augostini, Ruijiang Song, Sandra J Lee, Patrick Autissier, Ruth M Ruprecht, W Evan Secor

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Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques. by Konstantin Virnik, Margherita Rosati, Alexei Medvedev, Aaron Scanlan, Gabrielle Walsh, Frances Dayton, Kate E Broderick, Mark Lewis, Yvonne Bryson, Jeffrey D Lifson, Ruth M Ruprecht, Barbara K Felber, Ira Berkower

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Live attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaques. by Siddappa N Byrareddy, Mila Ayash-Rashkovsky, Victor G Kramer, Sandra J Lee, Mick Correll, Francis J Novembre, Francois Villinger, Welkin E Johnson, Agneta von Gegerfelt, Barbara K Felber, Ruth M Ruprecht

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Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41. by Mei-Yun Zhang, Tingting Yuan, Jingjing Li, Andrew Rosa Borges, Jennifer D Watkins, Javier Guenaga, Zheng Yang, Yanping Wang, Richard Wilson, Yuxing Li, Victoria R Polonis, Seth H Pincus, Ruth M Ruprecht, Dimiter S Dimitrov

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R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes. by Michael Santosuosso, Elda Righi, E David Hill, Pierre R Leblanc, Brett Kodish, Hari N Mylvaganam, Nagadenahalli B Siddappa, Liljana Stevceva, Shiu-Lok Hu, Musie Ghebremichael, Agnes-L Chenine, Avi-Hai Hovav, Ruth M Ruprecht, Mark C Poznansky

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Isolation of monoclonal antibodies with predetermined conformational epitope specificity. by Anton M Sholukh, Muhammad M Mukhtar, Michael Humbert, Sosthène S Essono, Jennifer D Watkins, Hemant K Vyas, Vivekanandan Shanmuganathan, Girish Hemashettar, Maria Kahn, Shiu-Lok Hu, David C Montefiori, Victoria R Polonis, Peter H Schur, Ruth M Ruprecht

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Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection. by Samir K Lakhashe, Wendy Wang, Nagadenahalli B Siddappa, Girish Hemashettar, Patricia Polacino, Shiu-Lok Hu, François Villinger, James G Else, Francis J Novembre, John K Yoon, Sandra J Lee, David C Montefiori, Ruth M Ruprecht, Robert A Rasmussen

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R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models. by Nagadenahalli B Siddappa, Jennifer D Watkins, Klemens J Wassermann, Ruijiang Song, Wendy Wang, Victor G Kramer, Samir Lakhashe, Michael Santosuosso, Mark C Poznansky, Francis J Novembre, François Villinger, James G Else, David C Montefiori, Robert A Rasmussen, Ruth M Ruprecht

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Lymphocytes upregulate CD36 in adipose tissue and liver by Jacob Couturier, Alli M. Nuotio-Antar, Neeti Agarwal, Gregory K. Wilkerson, Pradip Saha, Viraj Kulkarni, Samir K. Lakhashe, Juan Esquivel, Pramod N. Nehete, Ruth M. Ruprecht, K. Jagannadha Sastry, Jennifer M. Meyer, Lori R. Hill, Jordan E. Lake, Ashok Balasubramanyam, Dorothy E. Lewis

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Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells. by Sandeep Gupta, Johannes S. Gach, Juan C. Becerra, Tran B. Phan, Jeffrey Pudney, Zina Moldoveanu, Sarah B. Joseph, Gary Landucci, Medalyn Jude Supnet, Li-Hua Ping, Davide Corti, Brian Moldt, Zdenek Hel, Antonio Lanzavecchia, Ruth M. Ruprecht, Dennis R. Burton, Jiri Mestecky, Deborah J. Anderson, Donald N. Forthal

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An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV. by Jennifer D Watkins, Nagadenahalli B Siddappa, Samir K Lakhashe, Michael Humbert, Anton Sholukh, Girish Hemashettar, Yin Ling Wong, John K Yoon, Wendy Wang, Francis J Novembre, Francois Villinger, Chris Ibegbu, Kalpana Patel, Davide Corti, Gloria Agatic, Fabrizia Vanzetta, Siro Bianchi, Jonathan L Heeney, Federica Sallusto, Antonio Lanzavecchia, Ruth M Ruprecht

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