Altered gene expression in blood and sputum in COPD frequent exacerbators in the ECLIPSE cohort. by Dave Singh, Steven M Fox, Ruth Tal-Singer, Stewart Bates, John H Riley, Bartolome Celli

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Multiple biomarkers predict disease severity, progression and mortality in COPD by Rachel L. Zemans, Sean Jacobson, Jason Keene, Katerina Kechris, Bruce E. Miller, Ruth Tal-Singer, Russell P. Bowler

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DSP variants may be associated with longitudinal change in quantitative emphysema by Woori Kim, Michael H. Cho, Phuwanat Sakornsakolpat, David A. Lynch, Harvey O. Coxson, Ruth Tal-Singer, Edwin K. Silverman, Terri H. Beaty

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CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial by Aili L. Lazaar, Bruce E. Miller, Alison C. Donald, Thomas Keeley, Claire Ambery, John Russell, Henrik Watz, Ruth Tal-Singer, for 205724 Investigators

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Plasma microfibrillar-associated protein 4 is not prognostic of emphysema progression but is associated with cardiovascular disease history and mortality in COPD patients by Sofie Lock Johansson, Helle Wulf-Johansson, Anders Schlosser, Ingrid L. Titlestad, Bruce Miller, Ruth Tal-Singer, Uffe Holmskov, Jørgen Vestbo, Grith Lykke Sørensen

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CXCL-8-dependent and -independent neutrophil activation in COPD: experiences from a pilot study of the CXCR2 antagonist danirixin by Holly R. Keir, Hollian Richardson, Christina Fillmore, Amelia Shoemark, Aili L. Lazaar, Bruce E. Miller, Ruth Tal-Singer, James D. Chalmers, Divya Mohan

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P7.14 SERUM INFLAMMATORY MARKERS ARE POOR PREDICTORS OF VASCULAR INFLAMMATION AND VASCULAR INFLAMMATION DOES NOT DETERMINE AORTIC STIFFNESS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE... by Marie Fisk*, Divya Mohan, Joseph Cheriyan, Julia Forman, Carmel M. McEniery, John R. Cockcroft, Ruth Tal-Singer, Michael I. Polkey, Ian B. Wilkinson

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Circulating testosterone levels and health outcomes in chronic obstructive pulmonary disease: results from ECLIPSE and ERICA by Divya Mohan, Carmel M McEniery, Marie Fisk, Joseph Cheriyan, Bruce E Miller, Ruth Tal-Singer, Michael I Polkey, Holly Pavey, Ian Wilkinson, Richard Casaburi

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Blood neutrophil counts are associated with exacerbation frequency and mortality in COPD by Mike Lonergan, Alison J. Dicker, Megan L. Crichton, Holly R. Keir, Melissa K. Van Dyke, Hana Mullerova, Bruce E. Miller, Ruth Tal-Singer, James D. Chalmers

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Quantitative analysis of dynamic 18F-FDG PET/CT for measurement of lung inflammation by Christopher Coello, Marie Fisk, Divya Mohan, Frederick J. Wilson, Andrew P. Brown, Michael I. Polkey, Ian Wilkinson, Ruth Tal-Singer, Philip S. Murphy, Joseph Cheriyan, Roger N. Gunn

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Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort by Sarah R. Rønnow, Lasse L. Langholm, Morten A. Karsdal, Tina Manon-Jensen, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana J. Leeming, Jannie M. B. Sand

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Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort by Sarah Rank Rønnow, Jannie Marie Bülow Sand, Lasse Løcke Langholm, Tina Manon-Jensen, Morten Asser Karsdal, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana Julie Leeming

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Vascular inflammation and aortic stiffness: potential mechanisms of increased vascular risk in chronic obstructive pulmonary disease by Marie Fisk, Joseph Cheriyan, Divya Mohan, Carmel M. McEniery, Julia Forman, John R. Cockcroft, James H. F. Rudd, Ruth Tal-Singer, Nicholas S. Hopkinson, Michael I. Polkey, Ian B. Wilkinson

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Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis by Rosa Faner, Jarrett D. Morrow, Sandra Casas-Recasens, Suzanne M. Cloonan, Guillaume Noell, Alejandra López-Giraldo, Ruth Tal-Singer, Bruce E. Miller, Edwin K. Silverman, Alvar Agustí, Craig P. Hersh

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The COPD Foundation's COPD360Net Initiative Approach to Patient-Centric Drug Development: A Case Study in Using Patient Surveys to Inform New Treatments for Viral Respiratory Infec... by Ruth Tal-Singer PhD, Bruce E Miller PhD, Jean M Rommes PhD, Mark A Luttmann BS, Christophe Demaison PhD, M Bradley Drummond MD, Cara B Pasquale MPH

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1.6 THE BODE INDEX PROGNOSTIC SCORE IS AN INDEPENDENT DETERMINANT OF ARTERIAL STIFFNESS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) by Marie Fisk*, Nichola Gale, Divya Mohan, Carmel M. McEniery, Julia Forman, Charlotte E. Bolton, William MacNee, John R. Cockcroft, Joseph Cheriyan, Ruth Tal-Singer, Michael I. Polkey, Ian B. Wilkinson

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Investigation of the Clinical, Radiological and Biological Factors Associated with Disease Progression, Phenotypes and Endotypes of COPD in China (COMPASS): study design, protocol... by Zhenyu Liang, Nanshan Zhong, Rongchang Chen, Qianli Ma, Yongchang Sun, Fuqiang Wen, Ruth Tal-Singer, Bruce E. Miller, Julie Yates, Jie Song, Chris Compton, Beulah Ji, Li Wu, Yang Yang, Paul Jones, Jinping Zheng

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It’s more than low BMI: prevalence of cachexia and associated mortality in COPD by Merry-Lynn N. McDonald, Emiel F. M. Wouters, Erica Rutten, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Marcas Bamman, Bartolome Celli, Alvar Agusti, Ruth Tal-Singer, Craig P. Hersh, Mark Dransfield, Edwin K. Silverman

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The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised d... by Marie Fisk, Joseph Cheriyan, Divya Mohan, Julia Forman, Kaisa M Mäki-Petäjä, Carmel M McEniery, Jonathan Fuld, James H F Rudd, Nicholas S Hopkinson, David A Lomas, John R Cockcroft, Ruth Tal-Singer, Michael I Polkey, Ian B Wilkinson

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Quantitative 18F-fluorodeoxyglucose positron emission tomography/computed tomography to assess pulmonary inflammation in COPD by Laurence Vass, Marie Fisk, Joseph Cheriyan, Divya Mohan, Julia Forman, Adelola Oseni, Anand Devaraj, Kaisa M. Mäki-Petäjä, Carmel M. McEniery, Jonathan Fuld, Nicholas S. Hopkinson, David A. Lomas, John R. Cockcroft, Ruth Tal-Singer, Michael I. Polkey, Ian B. Wilkinson

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