Adefovir dipivoxil induces DNA replication stress and augments ATR inhibitor-related cytotoxicity by Patel, A, Seraia, E, Ebner, D, Ryan, AJ

CHK1 inhibition exacerbates replication stress induced by IGF blockade by Wu, X, Seraia, E, Hatch, SB, Wan, X, Ebner, DV, Aroldi, F, Jiang, Y, Ryan, AJ, Bogenrieder, T, Weyer-Czernilofsky, U, Rieunier, G, Macaulay, VM

Olaparib increases the therapeutic index of hemithoracic irradiation compared with hemithoracic irradiation alone in a mouse lung cancer model by Jiang, Y, Martin, J, Alkadhimi, M, Shigemori, K, Kinchesh, P, Gilchrist, S, Kersemans, V, Smart, S, Thompson, JM, Hill, MA, O'Connor, MJ, Davies, BR, Ryan, AJ

Targeting IGF perturbs global replication through ribonucleotide reductase dysfunction by Rieunier, G, Wu, X, Harris, LE, Mills, JV, Nandakumar, A, Colling, L, Seraia, E, Hatch, SB, Ebner, DV, Folkes, LK, Weyer-Czernilofsky, U, Bogenrieder, T, Ryan, AJ, Macaulay, VM

Inhibiting WEE1 selectively kills histone H3K36me3-deficient cancers by dNTP starvation by Pfister, SX, Markkanen, E, Jiang, Y, Sarkar, S, Woodcock, M, Orlando, G, Mavrommati, I, Pai, C-C, Zalmas, L, Drobnitzky, N, Dianov, GL, Verrill, C, Macaulay, VM, Ying, S, La Thangue, NB, D'Angiolella, V, Ryan, AJ, Humphrey, TC

Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy by Willoughby, CE, Jiang, Y, Thomas, HD, Willmore, E, Kyle, S, Wittner, A, Phillips, N, Zhao, Y, Tudhope, SJ, Prendergast, L, Junge, G, Lourenco, LM, Finlay, MRV, Turner, P, Munck, JM, Griffin, RJ, Rennison, T, Pickles, J, Cano, C, Newell, DR, Reeves, HL, Ryan, AJ, Wedge, SR

Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response by Zhang, P, Kitchen-Smith, I, Xiong, L, Stracquadanio, G, Brown, K, Richter, PH, Wallace, MD, Bond, E, Sahgal, N, Moore, S, Nornes, S, De Val, S, Surakhy, M, Sims, D, Wang, X, Bell, DA, Zeron-Medina, J, Jiang, Y, Ryan, AJ, Selfe, JL, Shipley, J, Kar, S, Pharoah, PDP, Loveday, C, Jansen, R, Grochola, LF, Palles, C, Protheroe, A, Millar, V, Ebner, DV, Pagadala, M, Blagden, SP, Maughan, TS, Domingo, E, Tomlinson, I, Turnbull, C, Carter, H, Bond, GL