Metabolomics and 13C labelled glucose tracing to identify carbon incorporation into aberrant cell membrane glycans in cancer حسب Alfredo Reyes-Oliveras, Abigail E. Ellis, Ryan D. Sheldon, Brian Haab

احصل على النص الكامل

The Emerging Role of Hepatocellular eNOS in Non-alcoholic Fatty Liver Disease Development حسب Rory P. Cunningham, Rory P. Cunningham, Ryan D. Sheldon, R. Scott Rector, R. Scott Rector, R. Scott Rector

احصل على النص الكامل

New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape حسب Chad R. Schultz, Ryan D. Sheldon, Huirong Xie, Elena Y. Demireva, Katie L. Uhl, Dalen W. Agnew, Dirk Geerts, André S. Bachmann

احصل على النص الكامل

PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression حسب Hannah Guak, Ryan D. Sheldon, Ian Beddows, Alexandra Vander Ark, Matthew J. Weiland, Hui Shen, Russell G. Jones, Julie St-Pierre, Eric H. Ma, Connie M. Krawczyk

احصل على النص الكامل

Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides حسب James H. Schofield, Joseph Longo, Ryan D. Sheldon, Emma Albano, Abigail E. Ellis, Mark A. Hawk, Sean Murphy, Loan Duong, Sharif Rahmy, Xin Lu, Russell G. Jones, Zachary T. Schafer

احصل على النص الكامل

NF1 deficiency drives metabolic reprogramming in ER+ breast cancer حسب Rachel (Rae) J. House, Elizabeth A. Tovar, Luke N. Redlon, Curt J. Essenburg, Patrick S. Dischinger, Abigail E. Ellis, Ian Beddows, Ryan D. Sheldon, Evan C. Lien, Carrie R. Graveel, Matthew R. Steensma

احصل على النص الكامل

The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity حسب Adam J. Rauckhorst, Lawrence R. Gray, Ryan D. Sheldon, Xiaorong Fu, Alvin D. Pewa, Charlotte R. Feddersen, Adam J. Dupuy, Katherine N. Gibson-Corley, James E. Cox, Shawn C. Burgess, Eric B. Taylor

احصل على النص الكامل

ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis حسب Diane DeZwaan-McCabe, Ryan D. Sheldon, Michelle C. Gorecki, Deng-Fu Guo, Erica R. Gansemer, Randal J. Kaufman, Kamal Rahmouni, Matthew P. Gillum, Eric B. Taylor, Lynn M. Teesch, D. Thomas Rutkowski

احصل على النص الكامل

Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-‘omics analysis of the liver metabolic response to viral infection حسب Zachary B Madaj, Michael S. Dahabieh, Vijayvardhan Kamalumpundi, Brejnev Muhire, J. Pettinga, Rebecca A. Siwicki, Abigail E. Ellis, Christine Isaguirre, Martha L. Escobar Galvis, Lisa DeCamp, Russell G. Jones, Scott A. Givan, Marie Adams, Ryan D. Sheldon

احصل على النص الكامل

Mitochondrial citrate metabolism and efflux regulate BeWo differentiation حسب Renee M. Mahr, Snehalata Jena, Sereen K. Nashif, Alisa B. Nelson, Adam J. Rauckhorst, Ferrol I. Rome, Ryan D. Sheldon, Curtis C. Hughey, Patrycja Puchalska, Micah D. Gearhart, Eric B. Taylor, Peter A. Crawford, Sarah A. Wernimont

احصل على النص الكامل

A diverse proteome is present and enzymatically active in metabolite extracts حسب Rachel (Rae) J. House, Molly T. Soper-Hopper, Michael P. Vincent, Abigail E. Ellis, Colt D. Capan, Zachary B. Madaj, Emily Wolfrum, Christine N. Isaguirre, Carlos D. Castello, Amy B. Johnson, Martha L. Escobar Galvis, Kelsey S. Williams, Hyoungjoo Lee, Ryan D. Sheldon

احصل على النص الكامل

Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis حسب Sean C. Tompkins, Ryan D. Sheldon, Adam J. Rauckhorst, Maria F. Noterman, Shane R. Solst, Jane L. Buchanan, Kranti A. Mapuskar, Alvin D. Pewa, Lawrence R. Gray, Lalita Oonthonpan, Arpit Sharma, Diego A. Scerbo, Adam J. Dupuy, Douglas R. Spitz, Eric B. Taylor

احصل على النص الكامل

Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment حسب Said Izreig, Alexandra Gariepy, Irem Kaymak, Hannah R. Bridges, Ariel O. Donayo, Gaëlle Bridon, Lisa M. DeCamp, Susan M. Kitchen-Goosen, Daina Avizonis, Ryan D. Sheldon, Rob C. Laister, Mark D. Minden, Nathalie A. Johnson, Thomas F. Duchaine, Marc S. Rudoltz, Sanghee Yoo, Michael N. Pollak, Kelsey S. Williams, Russell G. Jones

احصل على النص الكامل

Itaconate confers tolerance to late NLRP3 inflammasome activation حسب Monika Bambouskova, Lucie Potuckova, Tomas Paulenda, Martina Kerndl, Denis A. Mogilenko, Kate Lizotte, Amanda Swain, Sebastian Hayes, Ryan D. Sheldon, Hyeryun Kim, Unnati Kapadnis, Abigail E. Ellis, Christine Isaguirre, Samantha Burdess, Anwesha Laha, Gaya K. Amarasinghe, Victor Chubukov, Thomas P. Roddy, Michael S. Diamond, Russell G. Jones, Donald M. Simons, Maxim N. Artyomov

احصل على النص الكامل

Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness حسب Arpit Sharma, Lalita Oonthonpan, Ryan D Sheldon, Adam J Rauckhorst, Zhiyong Zhu, Sean C Tompkins, Kevin Cho, Wojciech J Grzesik, Lawrence R Gray, Diego A Scerbo, Alvin D Pewa, Emily M Cushing, Michael C Dyle, James E Cox, Chris Adams, Brandon S Davies, Richard K Shields, Andrew W Norris, Gary Patti, Leonid V Zingman, Eric B Taylor

احصل على النص الكامل