Metabolomics and 13C labelled glucose tracing to identify carbon incorporation into aberrant cell membrane glycans in cancer ανά Alfredo Reyes-Oliveras, Abigail E. Ellis, Ryan D. Sheldon, Brian Haab

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The Emerging Role of Hepatocellular eNOS in Non-alcoholic Fatty Liver Disease Development ανά Rory P. Cunningham, Rory P. Cunningham, Ryan D. Sheldon, R. Scott Rector, R. Scott Rector, R. Scott Rector

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New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape ανά Chad R. Schultz, Ryan D. Sheldon, Huirong Xie, Elena Y. Demireva, Katie L. Uhl, Dalen W. Agnew, Dirk Geerts, André S. Bachmann

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PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression ανά Hannah Guak, Ryan D. Sheldon, Ian Beddows, Alexandra Vander Ark, Matthew J. Weiland, Hui Shen, Russell G. Jones, Julie St-Pierre, Eric H. Ma, Connie M. Krawczyk

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Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides ανά James H. Schofield, Joseph Longo, Ryan D. Sheldon, Emma Albano, Abigail E. Ellis, Mark A. Hawk, Sean Murphy, Loan Duong, Sharif Rahmy, Xin Lu, Russell G. Jones, Zachary T. Schafer

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NF1 deficiency drives metabolic reprogramming in ER+ breast cancer ανά Rachel (Rae) J. House, Elizabeth A. Tovar, Luke N. Redlon, Curt J. Essenburg, Patrick S. Dischinger, Abigail E. Ellis, Ian Beddows, Ryan D. Sheldon, Evan C. Lien, Carrie R. Graveel, Matthew R. Steensma

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The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity ανά Adam J. Rauckhorst, Lawrence R. Gray, Ryan D. Sheldon, Xiaorong Fu, Alvin D. Pewa, Charlotte R. Feddersen, Adam J. Dupuy, Katherine N. Gibson-Corley, James E. Cox, Shawn C. Burgess, Eric B. Taylor

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ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis ανά Diane DeZwaan-McCabe, Ryan D. Sheldon, Michelle C. Gorecki, Deng-Fu Guo, Erica R. Gansemer, Randal J. Kaufman, Kamal Rahmouni, Matthew P. Gillum, Eric B. Taylor, Lynn M. Teesch, D. Thomas Rutkowski

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Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-‘omics analysis of the liver metabolic response to viral infection ανά Zachary B Madaj, Michael S. Dahabieh, Vijayvardhan Kamalumpundi, Brejnev Muhire, J. Pettinga, Rebecca A. Siwicki, Abigail E. Ellis, Christine Isaguirre, Martha L. Escobar Galvis, Lisa DeCamp, Russell G. Jones, Scott A. Givan, Marie Adams, Ryan D. Sheldon

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Mitochondrial citrate metabolism and efflux regulate BeWo differentiation ανά Renee M. Mahr, Snehalata Jena, Sereen K. Nashif, Alisa B. Nelson, Adam J. Rauckhorst, Ferrol I. Rome, Ryan D. Sheldon, Curtis C. Hughey, Patrycja Puchalska, Micah D. Gearhart, Eric B. Taylor, Peter A. Crawford, Sarah A. Wernimont

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A diverse proteome is present and enzymatically active in metabolite extracts ανά Rachel (Rae) J. House, Molly T. Soper-Hopper, Michael P. Vincent, Abigail E. Ellis, Colt D. Capan, Zachary B. Madaj, Emily Wolfrum, Christine N. Isaguirre, Carlos D. Castello, Amy B. Johnson, Martha L. Escobar Galvis, Kelsey S. Williams, Hyoungjoo Lee, Ryan D. Sheldon

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Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis ανά Sean C. Tompkins, Ryan D. Sheldon, Adam J. Rauckhorst, Maria F. Noterman, Shane R. Solst, Jane L. Buchanan, Kranti A. Mapuskar, Alvin D. Pewa, Lawrence R. Gray, Lalita Oonthonpan, Arpit Sharma, Diego A. Scerbo, Adam J. Dupuy, Douglas R. Spitz, Eric B. Taylor

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Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment ανά Said Izreig, Alexandra Gariepy, Irem Kaymak, Hannah R. Bridges, Ariel O. Donayo, Gaëlle Bridon, Lisa M. DeCamp, Susan M. Kitchen-Goosen, Daina Avizonis, Ryan D. Sheldon, Rob C. Laister, Mark D. Minden, Nathalie A. Johnson, Thomas F. Duchaine, Marc S. Rudoltz, Sanghee Yoo, Michael N. Pollak, Kelsey S. Williams, Russell G. Jones

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Itaconate confers tolerance to late NLRP3 inflammasome activation ανά Monika Bambouskova, Lucie Potuckova, Tomas Paulenda, Martina Kerndl, Denis A. Mogilenko, Kate Lizotte, Amanda Swain, Sebastian Hayes, Ryan D. Sheldon, Hyeryun Kim, Unnati Kapadnis, Abigail E. Ellis, Christine Isaguirre, Samantha Burdess, Anwesha Laha, Gaya K. Amarasinghe, Victor Chubukov, Thomas P. Roddy, Michael S. Diamond, Russell G. Jones, Donald M. Simons, Maxim N. Artyomov

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Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness ανά Arpit Sharma, Lalita Oonthonpan, Ryan D Sheldon, Adam J Rauckhorst, Zhiyong Zhu, Sean C Tompkins, Kevin Cho, Wojciech J Grzesik, Lawrence R Gray, Diego A Scerbo, Alvin D Pewa, Emily M Cushing, Michael C Dyle, James E Cox, Chris Adams, Brandon S Davies, Richard K Shields, Andrew W Norris, Gary Patti, Leonid V Zingman, Eric B Taylor

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