The role of the complement system in disc degeneration and Modic changes by Irina Heggli, Graciosa Q. Teixeira, James C. Iatridis, Cornelia Neidlinger‐Wilke, Stefan Dudli

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Intervertebral disc cell chondroptosis elicits neutrophil response in Staphylococcus aureus spondylodiscitis by Tiziano A. Schweizer, Federica Andreoni, Claudio Acevedo, Thomas C. Scheier, Irina Heggli, Irina Heggli, Ewerton Marques Maggio, Nadia Eberhard, Silvio D. Brugger, Stefan Dudli, Stefan Dudli, Annelies S. Zinkernagel, Annelies S. Zinkernagel

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Bone marrow stromal cells in Modic type 1 changes promote neurite outgrowth by Tamara Mengis, Tamara Mengis, Nick Herger, Nick Herger, Irina Heggli, Irina Heggli, Jan Devan, Jan Devan, José Miguel Spirig, Christoph J. Laux, Florian Brunner, Mazda Farshad, Oliver Distler, Stefan Dudli, Stefan Dudli

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Should Degenerated Intervertebral Discs of Patients with Modic Type 1 Changes Be Treated with Mesenchymal Stem Cells? by Nick Herger, Paola Bermudez-Lekerika, Mazda Farshad, Christoph E. Albers, Oliver Distler, Benjamin Gantenbein, Stefan Dudli

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Impacts of priming on distinct immunosuppressive mechanisms of mesenchymal stromal cells under translationally relevant conditions by Nick Herger, Irina Heggli, Tamara Mengis, Jan Devan, Leonardo Arpesella, Florian Brunner, Oliver Distler, Stefan Dudli

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Acrylonitrile and Pullulan Based Nanofiber Mats as Easily Accessible Scaffolds for 3D Skin Cell Models Containing Primary Cells by Markus Rimann, Astrid Jüngel, Sara Mousavi, Nicole Moeschlin, Maurizio Calcagni, Karin Wuertz-Kozak, Florian Brunner, Stefan Dudli, Oliver Distler, Christian Adlhart

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FGF2 overrides key pro-fibrotic features of bone marrow stromal cells isolated from Modic type 1 change patients by I Heggli, U Blache, N Herger, T Mengis, PK Jaeger, R Schuepbach, N Farshad-Amacker, F Brunner, JG Snedeker, M Farshad, O Distler, S Dudli

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Pro-Inflammatory and Neurotrophic Factor Responses of Cells Derived from Degenerative Human Intervertebral Discs to the Opportunistic Pathogen <i>Cutibacterium acnes</i> by Manu N. Capoor, Anna Konieczna, Andrew McDowell, Filip Ruzicka, Martin Smrcka, Radim Jancalek, Karel Maca, Michael Lujc, Fahad S. Ahmed, Christof Birkenmaier, Stefan Dudli, Ondrej Slaby

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Pulsed electromagnetic fields reduce acute inflammation in the injured rat‐tail intervertebral disc by Andrew K. Chan, Xinyan Tang, Nikhil V. Mummaneni, Dezba Coughlin, Ellen Liebenberg, Annie Ouyang, Stefan Dudli, Michael Lauricella, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Jeffrey C. Lotz

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Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes by I. Heggli, T. Mengis, C.J. Laux, L. Opitz, N. Herger, D. Menghini, R. Schuepbach, N.A. Farshad-Amacker, F. Brunner, A.J. Fields, M. Farshad, O. Distler, S. Dudli

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CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes by Stefan Dudli, Agnieszka Karol, Luca Giudici, Irina Heggli, Christoph J Laux, Jose M Spirig, Florian Wanivenhaus, Michael Betz, Christoph Germann, Nadja Farshad-Amacker, Florian Brunner, Oliver Distler, Mazda Farshad

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Cartilaginous endplates: A comprehensive review on a neglected structure in intervertebral disc research by Katherine B. Crump, Ahmad Alminnawi, Paola Bermudez‐Lekerika, Roger Compte, Francesco Gualdi, Terence McSweeney, Estefano Muñoz‐Moya, Andrea Nüesch, Liesbet Geris, Stefan Dudli, Jaro Karppinen, Jérôme Noailly, Christine Le Maitre, Benjamin Gantenbein

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Modic type 2 changes are fibroinflammatory changes with complement system involvement adjacent to degenerated vertebral endplates by Irina Heggli, Christoph J. Laux, Tamara Mengis, Agnieszka Karol, Frédéric Cornaz, Nick Herger, Borbala Aradi‐Vegh, Jonas Widmer, Marco D. Burkhard, Nadja A. Farshad‐Amacker, Sibylle Pfammatter, Witold E. Wolski, Florian Brunner, Oliver Distler, Mazda Farshad, Stefan Dudli

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Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling Are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes) by Stefan Dudli, Alexander Ballatori, Anne-Christine Bay-Jensen, Zachary L. McCormick, Conor W. O’Neill, Sibel Demir-Deviren, Roland Krug, Irina Heggli, Astrid Juengel, Jaro Karppinen, Florian Brunner, Mazda Farshad, Oliver Distler, Jeffrey C. Lotz, Aaron J. Fields

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Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section by Alon Lai, Jennifer Gansau, Sarah E. Gullbrand, James Crowley, Carla Cunha, Stefan Dudli, Julie B. Engiles, Marion Fusellier, Raquel M. Goncalves, Daisuke Nakashima, Jeffrey Okewunmi, Matthew Pelletier, Steven M. Presciutti, Jordy Schol, Yoshiki Takeoka, Sidong Yang, Takashi Yurube, Yejia Zhang, James C. Iatridis

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Harmonization and standardization of nucleus pulposus cell extraction and culture methods by Shaghayegh Basatvat, Frances C. Bach, Marcos N. Barcellona, Abbie L. Binch, Conor T. Buckley, Brian Bueno, Nadeen O. Chahine, Ana Chee, Laura B. Creemers, Stefan Dudli, Bailey Fearing, Stephen J. Ferguson, Jennifer Gansau, Benjamin Gantenbein, Rahul Gawri, Juliane D. Glaeser, Sibylle Grad, Julien Guerrero, Lisbet Haglund, Paula A. Hernandez, Judith A. Hoyland, Charles Huang, James C. Iatridis, Svenja Illien‐Junger, Liufang Jing, Petra Kraus, Lisanne T. Laagland, Gernot Lang, Victor Leung, Zhen Li, Thomas Lufkin, Josette C. vanMaanen, Emily E. McDonnell, Chris J. Panebianco, Steven M. Presciutti, Sanjna Rao, Stephen M. Richardson, Sarah Romereim, Tara C. Schmitz, Jordy Schol, Lori Setton, Dmitriy Sheyn, Joseph W. Snuggs, Y. Sun, Xiaohong Tan, Marianna A. Tryfonidou, Nam Vo, Dong Wang, Brandon Williams, Rebecca Williams, S. Tim Yoon, Christine L. Le Maitre

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