Novel Molecular Insights into Leukemic Evolution of Myeloproliferative Neoplasms: A Single Cell Perspective by Sebastiano Rontauroli, Chiara Carretta, Sandra Parenti, Matteo Bertesi, Rossella Manfredini

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Genomic Analysis of Hematopoietic Stem Cell at the Single-Cell Level: Optimization of Cell Fixation and Whole Genome Amplification (WGA) Protocol by Chiara Carretta, Selene Mallia, Elena Genovese, Sandra Parenti, Sebastiano Rontauroli, Elisa Bianchi, Sebastian Fantini, Stefano Sartini, Lara Tavernari, Enrico Tagliafico, Rossella Manfredini

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P983: SINGLE CELL ANALYSIS ALLOWS THE EARLY DETECTION OF LEUKEMIC CLONES IN MPN PATIENTS by C. Carretta, S. Parenti, S. Mallia, S. Rontauroli, C. Chiereghin, S. Castellano, E. Bianchi, E. Genovese, S. Sartini, L. Tavernari, M. Mirabile, M. G. Della Porta, R. Manfredini

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P999: ERK1/2 INHIBITION REDUCES OSTEOPONTIN PLASMA LEVELS AND BONE MARROW FIBROSIS IN A MYELOFIBROSIS MOUSE MODEL by S. Rontauroli, E. Bianchi, L. Tavernari, M. Dall’Ora, G. Grisendi, M. Mirabile, S. Sartini, E. Genovese, C. Carretta, S. Mallia, S. Parenti, L. Fabbiani, N. Bartalucci, L. Losi, M. Dominici, A. M. Vannucchi, R. Manfredini

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Mutated clones driving leukemic transformation are already detectable at the single-cell level in CD34-positive cells in the chronic phase of primary myelofibrosis by Sandra Parenti, Sebastiano Rontauroli, Chiara Carretta, Selene Mallia, Elena Genovese, Chiara Chiereghin, Clelia Peano, Lara Tavernari, Elisa Bianchi, Sebastian Fantini, Stefano Sartini, Oriana Romano, Silvio Bicciato, Enrico Tagliafico, Matteo Della Porta, Rossella Manfredini

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P1003: PERIPHERAL BLOOD CYTOTOXIC T CELLS SHOW EARLY EXHAUSTED FEATURES IN MYELOFIBROSIS PATIENTS by L. Tavernari, S. Rontauroli, M. Maccaferri, B. Mora, E. Bianchi, S. Parenti, E. Genovese, P. Guglielmelli, C. Carretta, S. Mallia, M. Mirabile, S. Sartini, C. Colasante, L. Potenza, F. Passamonti, E. Tagliafico, M. Luppi, A. M. Vannucchi, R. Manfredini

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P987: A DIFFERENT BALANCE IN OXIDATIVE STRESS RESPONSE IN CALR AND JAK2 MUTATED MYELOFIBROSIS PATIENTS CORRELATES WITH CLINICAL OUTCOME by E. Genovese, M. Mirabile, S. Rontauroli, S. Sartini, S. Fantini, L. Tavernari, M. Maccaferri, P. Guglielmelli, E. Bianchi, S. Parenti, C. Carretta, S. Mallia, S. Castellano, C. Colasante, M. Balliu, N. Bartalucci, R. Palmieri, T. Ottone, B. Mora, L. Potenza, F. Passamonti, M. T. Voso, M. Luppi, A. M. Vannucchi, E. Tagliafico, R. Manfredini

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P1000: INCREASED PLASMA LEVELS OF LNCRNAS ARE POTENTIAL PROGNOSTIC BIOMARKERS IN MYELOFIBROSIS by S. Sartini, S. Fantini, S. Rontauroli, M. Mirabile, E. Bianchi, F. Badii, M. Maccaferri, P. Guglielmelli, T. Ottone, R. Palmieri, E. Genovese, C. Carretta, S. Parenti, S. Mallia, L. Tavernari, C. Salvadori, F. Gesullo, C. Maccari, M. Zizza, A. Grande, S. Salmoiraghi, B. Mora, L. Potenza, V. Rosti, F. Passamonti, A. Rambaldi, M. T. Voso, C. Mecucci, E. Tagliafico, M. Luppi, A. M. Vannucchi, R. Manfredini

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The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis by Elena Genovese, Margherita Mirabile, Sebastiano Rontauroli, Stefano Sartini, Sebastian Fantini, Lara Tavernari, Monica Maccaferri, Paola Guglielmelli, Elisa Bianchi, Sandra Parenti, Chiara Carretta, Selene Mallia, Sara Castellano, Corrado Colasante, Manjola Balliu, Niccolò Bartalucci, Raffaele Palmieri, Tiziana Ottone, Barbara Mora, Leonardo Potenza, Francesco Passamonti, Maria Teresa Voso, Mario Luppi, Alessandro Maria Vannucchi, Enrico Tagliafico, Rossella Manfredini, on behalf of the Mynerva (MYeloid NEoplasms Research Venture AIRC)

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Increased Plasma Levels of lncRNAs <i>LINC01268</i>, <i>GAS5</i> and <i>MALAT1</i> Correlate with Negative Prognostic Factors in Myelofibrosis by Sebastian Fantini, Sebastiano Rontauroli, Stefano Sartini, Margherita Mirabile, Elisa Bianchi, Filippo Badii, Monica Maccaferri, Paola Guglielmelli, Tiziana Ottone, Raffaele Palmieri, Elena Genovese, Chiara Carretta, Sandra Parenti, Selene Mallia, Lara Tavernari, Costanza Salvadori, Francesca Gesullo, Chiara Maccari, Michela Zizza, Alexis Grande, Silvia Salmoiraghi, Barbara Mora, Leonardo Potenza, Vittorio Rosti, Francesco Passamonti, Alessandro Rambaldi, Maria Teresa Voso, Cristina Mecucci, Enrico Tagliafico, Mario Luppi, Alessandro Maria Vannucchi, Rossella Manfredini

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