Targeting Leukemia Stem Cells in the Bone Marrow Niche by Sarah K. Tasian, Martin Bornhäuser, Sergio Rutella

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An Artificial Neural Network Integrated Pipeline for Biomarker Discovery Using Alzheimer's Disease as a Case Study by Dimitrios Zafeiris, Sergio Rutella, Graham Roy Ball

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Treatment of Crohn’s disease with colony-stimulating factors: An overview by Luisa Guidi, Giammarco Mocci, Manuela Marzo, Sergio Rutella

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Hypoxia Signaling in Parkinson’s Disease: There Is Use in Asking “What HIF?” by Laura Lestón Pinilla, Aslihan Ugun-Klusek, Sergio Rutella, Luigi A. De Girolamo

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Reverting Immune Suppression to Enhance Cancer Immunotherapy by Bella S. Guerrouahen, Cristina Maccalli, Chiara Cugno, Sergio Rutella, Emmanuel T. Akporiaye, Emmanuel T. Akporiaye

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Dissecting the Immune Landscape of Acute Myeloid Leukemia by Jan Davidson-Moncada, Elena Viboch, Sarah E. Church, Sarah E. Warren, Sergio Rutella

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Interleukin-21 induces the differentiation of human umbilical cord blood CD34^-lineage^-cells into pseudomature lytic NK cells by Scambia Giovanni, Corallo Maria, Procoli Annabella, Mariotti Andrea, Bonanno Giuseppina, Pierelli Luca, Rutella Sergio

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Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies by De Cristofaro Raimondo, Danese Silvio, Perillo Alessandro, Corallo Maria, Mariotti Andrea, Procoli Annabella, Bonanno Giuseppina, Scambia Giovanni, Rutella Sergio

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Cyclooxygenase-2 (COX-2) Inhibition Constrains Indoleamine 2,3-Dioxygenase 1 (IDO1) Activity in Acute Myeloid Leukaemia Cells by Sergio Rutella, Raimondo De Cristofaro, Franco Locatelli, Giuseppina Bonanno, Andrea Mariotti, Maria Grazia Iachininoto, Annabella Procoli, Eugenia Rosa Nuzzolo

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S129: ADOPTIVELY INFUSED MEMORY-LIKE (ML) NATURAL KILLER (NK) CELLS ELICIT ADAPTIVE IMMUNE RESPONSES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML) by Sergio Rutella, Amanda Cashen, John Muth, Jayakumar Vadakekolathu, Laura Arthur, Nitin Mahajan, Melissa Berrien-Elliott, Jan Davidson-Moncada, Todd Fehniger

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Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance by Raquel Alves, Ana Cristina Gonçalves, Sergio Rutella, António M. Almeida, Javier De Las Rivas, Ioannis P. Trougakos, Ana Bela Sarmento Ribeiro

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Immune Reconstitution After Autologous Hematopoietic Stem Cell Transplantation in Crohn’s Disease: Current Status and Future Directions. A Review on Behalf of the EBMT Autoimmune D... by Alan Graham Pockley, James O. Lindsay, Gemma A. Foulds, Sergio Rutella, John G. Gribben, Tobias Alexander, Tobias Alexander, John A. Snowden

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Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures by Corallo Maria, Fioravanti Daniela, Pandolfi Annino, Procoli Annabella, Mariotti Andrea, Iudicone Paola, Bonanno Giuseppina, Perillo Alessandro, Scambia Giovanni, Pierelli Luca, Rutella Sergio

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Flow cytometry and targeted immune transcriptomics identify distinct profiles in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors with or without interfe... by Raquel Alves, Stephanie E. B. McArdle, Jayakumar Vadakekolathu, Ana Cristina Gonçalves, Paulo Freitas-Tavares, Amélia Pereira, Antonio M. Almeida, Ana Bela Sarmento-Ribeiro, Sergio Rutella

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332 WU-NK-101, an off-the-shelf memory NK cell product, reverses immune checkpoint inhibitor (ICB) resistance with synergistic anti-tumor activity by Sergio Rutella, John Muth, Tom Leedom, Alexander Hamil, Basia Muz, Lena Luukkonen, Melissa Tran, Xia-Ha Li, Kristann Magee, Jayakmar Vadakekolathu, Ayman Kabakibi, Matthew L Cooper, Jan Davidson-Moncada

Characteristics of Tumor-Infiltrating Lymphocytes Prior to and During Immune Checkpoint Inhibitor Therapy by Ioana Plesca, Antje Tunger, Antje Tunger, Luise Müller, Rebekka Wehner, Rebekka Wehner, Rebekka Wehner, Xixi Lai, Marc-Oliver Grimm, Sergio Rutella, Michael Bachmann, Michael Bachmann, Michael Bachmann, Marc Schmitz, Marc Schmitz, Marc Schmitz

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Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma by Bonanno Giuseppina, Mariotti Andrea, Procoli Annabella, Folgiero Valentina, Natale Daniela, De Rosa Luca, Majolino Ignazio, Novarese Linda, Rocci Alberto, Gambella Manuela, Ciciarello Marilena, Scambia Giovanni, Palumbo Antonio, Locatelli Franco, De Cristofaro Raimondo, Rutella Sergio

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Gene Expression Profiling of FFPE Samples: A Titration Test by Harshitha Shobha Manjunath MSc, Moza Al Khulaifi BSc, Heba Sidahmed MD, Adham Ammar MD, Jayakumar Vadakekolathu PhD, Sergio Rutella MD, Muneera Jassim Al-Mohannadi MD, Mamoun Elawad MD, William Mifsud MD, Adrian Charles MD, Cristina Maccalli PhD, Sara Tomei PhD

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Immune dysfunction signatures predict outcomes and define checkpoint blockade–unresponsive microenvironments in acute myeloid leukemia by Sergio Rutella, Jayakumar Vadakekolathu, Francesco Mazziotta, Stephen Reeder, Tung-On Yau, Rupkatha Mukhopadhyay, Benjamin Dickins, Heidi Altmann, Michael Kramer, Hanna A. Knaus, Bruce R. Blazar, Vedran Radojcic, Joshua F. Zeidner, Andrea Arruda, Bofei Wang, Hussein A. Abbas, Mark D. Minden, Sarah K. Tasian, Martin Bornhäuser, Ivana Gojo, Leo Luznik

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P1426: WU-NK-101, AN ALLOGENEIC MEMORY NK CELL, FOR THE TREATMENT OF RELAPSE OR REFRACTORY (R/R) ACUTE MYELOID LEUKEMIA (AML) by J. J. Muth, M. E. Mathyer, B. Cruz, C. DuFour, T. Leedom, A. S. Hamil, S. Pouyanfard, M. Berrien-Elliot, L. Luukkonen, M. Tran, B. Tumala, N. Pomper, L. Arthur, M. Foster, J. Gorrochategui, P. Comune Pennacchi, D. Primo, J. Ballesteros, V. Tolstikov, M. A. Kiebish, P. Shah, J. Vadakekolathu, S. Rutella, T. A. Fehniger, R. Sullivan, A. Kabakibi, M. L. Cooper, J. Davidson-Moncada

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