A quantitative systems pharmacology (QSP) platform for preclinical to clinical translation of in-vivo CRISPR-Cas therapy by Devam A. Desai, Stephan Schmidt, Rodrigo Cristofoletti

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Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine’s Nonlinear Pharmacokinetics and Its Induction Potential on Cytochrome P450 3A4 and Cytochrome P4... by Xuefen Yin, Brian Cicali, Leyanis Rodriguez-Vera, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt

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Informing the risk assessment related to lactation and drug exposure: A physiologically based pharmacokinetic lactation model for pregabalin by Cameron Humerickhouse, Michelle Pressly, Zhoumeng Lin, Daphne Guinn, Sherbet Samuels, Elimika Pfuma Fletcher, Stephan Schmidt

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In memoriam Lambertus (“Bert”) A. Peletier 29 March 1937–16 December 2023: Furthering quantitative pharmacology through applied mathematics by Meindert Danhof, Piet H. van derGraaf, Teun M. Post, Sandra A. G. Visser, Klaas P. Zuideveld, Stephan Schmidt

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Real-world evidence and patient preference for subcutaneous intravenous natalizumab in the treatment of relapsing-remitting multiple sclerosis – initial results from the observati... by Ralf Gold, Stephan Schmidt, Florian Deisenhammer, Jeremias Motte, Nils Richter, Kirsi Taipale, Hans Christian Salmen, Christian Bohland, Ksenija Schirduan

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Interspecies Brain PBPK Modeling Platform to Predict Passive Transport through the Blood–Brain Barrier and Assess Target Site Disposition by Parsshava Mehta, Amira Soliman, Leyanis Rodriguez-Vera, Stephan Schmidt, Paula Muniz, Monica Rodriguez, Marta Forcadell, Emili Gonzalez-Perez, Valvanera Vozmediano

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Development of breakthrough bleeding model of combined‐oral contraceptives utilizing model‐based meta‐analysis by Huili Chen, Dain Chun, Karthik Lingineni, Serge Guzy, Rodrigo Cristofoletti, Joachim Hoechel, Tianze Jiao, Brian Cicali, Valvanera Vozmediano, Stephan Schmidt

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Advancing Precision Medicine: A Review of Innovative In Silico Approaches for Drug Development, Clinical Pharmacology and Personalized Healthcare by Lara Marques, Bárbara Costa, Mariana Pereira, Abigail Silva, Joana Santos, Leonor Saldanha, Isabel Silva, Paulo Magalhães, Stephan Schmidt, Nuno Vale

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Application of a dual mechanistic approach to support bilastine dose selection for older adults by Chaejin Kim, Valentina Lo Re, Monica Rodriguez, John C. Lukas, Nerea Leal, Cristina Campo, Aintzane García‐Bea, Elena Suarez, Stephan Schmidt, Valvanera Vozmediano

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Worse survival of hepatocellular cancer patients with membranous insulin receptor overexpression by Steffen Markus Heckl, Carolin Schneider, Lukas Kercher, Hans-Michael Behrens, Jan-Paul Gundlach, Alexander Bernsmeier, Stephan Schmidt, Sandra Krüger, Felix Braun, Rainer Günther, Thomas Becker, Stefan Schreiber, Christoph Röcken

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Type 1 diabetes prevention clinical trial simulator: Case reports of model‐informed drug development tool by Juan Francisco Morales, Marian Klose, Yannick Hoffert, Jagdeep T. Podichetty, Jackson Burton, Stephan Schmidt, Klaus Romero, Inish O'Doherty, Frank Martin, Martha Campbell‐Thompson, Michael J. Haller, Mark A. Atkinson, Sarah Kim

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Microphysiological system to address the opioid crisis: A novel multi-organ model of acute opioid overdose and recovery by Aakash Patel, Suruchi Poddar, Daniel Nierenberg, Stephanie Lang, Hao Wang, Camilly Pestana Pires DeMello, Julio Gamarra, Alisha Colon, Paula Kennedy, Jeffry Roles, Jules Klion, Will Bogen, Christopher Long, Xiufang Guo, Patrick Tighe, Stephan Schmidt, Michael L. Shuler, James J. Hickman

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