Novel mutant KRAS addiction signature predicts response to the combination of ERBB and MEK inhibitors in lung and pancreatic cancers by Katarzyna M. Tyc, Aslamuzzaman Kazi, Alok Ranjan, Rui Wang, Said M. Sebti

Get full text

Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIPs by Rony A. Francois, Anying Zhang, Kazim Husain, Chen Wang, Sean Hutchinson, Michael Kongnyuy, Surinder K. Batra, Domenico Coppola, Said M. Sebti, Mokenge P. Malafa

Get full text

Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim by Chunwei Cheng, Yan Liu, Maria E. Balasis, Nicholas L. Simmons, Jerry Li, Hao Song, Lili Pan, Yong Qin, K. C. Nicolaou, Said M. Sebti, Rongshi Li

Get full text

Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. by Pamela J Hodul, Yanbin Dong, Kazim Husain, Jose M Pimiento, Jiandong Chen, Anying Zhang, Rony Francois, Warren J Pledger, Domenico Coppola, Said M Sebti, Dung-Tsa Chen, Mokenge P Malafa

Get full text

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim by Chunwei Cheng, Yan Liu, Maria E. Balasis, Thomas P. Garner, Jerry Li, Nicholas L. Simmons, Norbert Berndt, Hao Song, Lili Pan, Yong Qin, K. C. Nicolaou, Evripidis Gavathiotis, Said M. Sebti, Rongshi Li

Get full text

Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. by Kiran Mahajan, Domenico Coppola, Sridevi Challa, Bin Fang, Y Ann Chen, Weiwei Zhu, Alexis S Lopez, John Koomen, Robert W Engelman, Charlene Rivera, Rebecca S Muraoka-Cook, Jin Q Cheng, Ernst Schönbrunn, Said M Sebti, H Shelton Earp, Nupam P Mahajan

Get full text