MSI-low, a real phenomenon which varies in frequency among cancer types. 著者: Halford, SE, Sawyer, E, Lambros, M, Gorman, P, Macdonald, N, Talbot, I, Foulkes, W, Gillett, C, Barnes, D, Akslen, L, Lee, K, Jacobs, I, Hanby, A, Ganesan, T, Salvesen, H, Bodmer, W, Tomlinson, I, Roylance, R

A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding 著者: Painter, J, Kaufmann, S, O'Mara, T, Hillman, K, Sivakumaran, H, Darabi, H, Cheng, T, Pearson, J, Kazakoff, S, Waddell, N, Hoivik, E, Goode, E, Scott, R, Tomlinson, I, Dunning, A, Easton, D, French, J, Salvesen, H, Pollock, P, Thompson, D, Spurdle, A, Edwards, S

A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding 著者: Painter, J, Kaufmann, S, O'Mara, T, Hillman, K, Sivakumaran, H, Darabi, H, Cheng, T, Pearson, J, Kazakoff, S, Waddell, N, Hoivik, E, Goode, E, Scott, R, Tomlinson, I, Dunning, A, Easton, D, French, J, Salvesen, H, Pollock, P, Thompson, D, Spurdle, A, Edwards, S

Genome-wide association study identifies a common variant associated with risk of endometrial cancer 著者: Spurdle, AB, Thompson, D, Ahmed, S, Ferguson, K, Healey, C, O'Mara, T, Walker, L, Montgomery, S, Dermitzakis, E, Fahey, P, Montgomery, G, Webb, P, Fasching, P, Beckmann, M, Ekici, AB, Hein, A, Lambrechts, D, Coenegrachts, L, Vergote, I, Amant, F, Salvesen, H, Trovik, J, Njolstad, T, Helland, H, Scott, R

Genome-wide association study identifies a common variant associated with risk of endometrial cancer. 著者: Spurdle, AB, Thompson, D, Ahmed, S, Ferguson, K, Healey, C, O'Mara, T, Walker, L, Montgomery, S, Dermitzakis, E, Fahey, P, Montgomery, G, Webb, P, Fasching, P, Beckmann, M, Ekici, AB, Hein, A, Lambrechts, D, Coenegrachts, L, Vergote, I, Amant, F, Salvesen, H, Trovik, J, Njolstad, T, Helland, H, Scott, R

Genome-wide association study identifies a possible susceptibility locus for endometrial cancer. 著者: Long, J, Zheng, W, Xiang, Y, Lose, F, Thompson, D, Tomlinson, I, Yu, H, Wentzensen, N, Lambrechts, D, Dörk, T, Dubrowinskaja, N, Goodman, M, Salvesen, H, Fasching, P, Scott, R, Delahanty, R, Zheng, Y, O'Mara, T, Healey, C, Hodgson, S, Risch, H, Yang, H, Amant, F, Turmanov, N, Schwake, A

Polymorphisms in inflammation pathway genes and endometrial cancer risk. 著者: Delahanty, R, Xiang, Y, Spurdle, A, Beeghly-Fadiel, A, Long, J, Thompson, D, Tomlinson, I, Yu, H, Lambrechts, D, Dörk, T, Goodman, M, Zheng, Y, Salvesen, H, Bao, P, Amant, F, Beckmann, M, Coenegrachts, L, Coosemans, A, Dubrowinskaja, N, Dunning, A, Runnebaum, I, Easton, D, Ekici, AB, Fasching, P, Halle, M

Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation 著者: Salvesen, H. B., Carter, Scott L., Mannelqvist, M., Dutt, Amit, Getz, Gad, Stefansson, I. M., Raeder, M. B., Sos, M. L., Engelsen, I. B., Trovik, J., Wik, E., Greulich, Heidi, Bo, T. H., Jonassen, I., Thomas, R. K., Zander, T., Garraway, Levi A., Oyan, A. M., Sellers, W. R., Kalland, K. H., Meyerson, Matthew L., Akslen, L. A., Beroukhim, Rameen

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Genetic risk score Mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer. 著者: Painter, J, O'Mara, T, Marquart, L, Webb, P, Attia, J, Medland, S, Cheng, T, Dennis, J, Holliday, E, McEvoy, M, Scott, R, Ahmed, S, Healey, C, Shah, M, Gorman, M, Martin, L, Hodgson, S, Beckmann, M, Ekici, A, Fasching, P, Hein, A, Rübner, M, Czene, K, Darabi, H, Hall, P, Li, J, Dork, T, Durst, M, Hillemanns, P, Runnebaum, I, Amant, F, Annibali, D, Depreeuw, J, Lambrechts, D, Neven, P, Cunningham, J, Dowdy, S, Goode, E, Fridley, B, Winham, S, Njolstad, T, Salvesen, H, Trovik, J, Werner, H, Ashton, K, Otton, G, Proietto, A, Mints, M, Tham, E, Bolla, M, Michailidou, K, Wang, Q, Tyrer, J, Hopper, J, Peto, J, Swerdlow, A, Burwinkel, B, Brenner, H, Meindl, A, Brauch, H, Lindblom, A, Chang-Claude, J, Couch, F, Giles, G, Kristensen, V, Cox, A, Pharoah, P, Tomlinson, I, Dunning, A, Easton, D, Thompson, D, Spurdle, A

Five endometrial cancer risk loci identified through genome-wide association analysis. 著者: Cheng, T, Thompson, D, O'Mara, T, Painter, J, Glubb, D, Flach, S, Lewis, A, French, J, Freeman-Mills, L, Church, D, Gorman, M, Martin, L, Hodgson, S, Webb, P, Attia, J, Holliday, E, McEvoy, M, Scott, R, Henders, A, Martin, N, Montgomery, G, Nyholt, D, Ahmed, S, Healey, C, Shah, M, Dennis, J, Fasching, P, Beckmann, M, Hein, A, Ekici, A, Hall, P, Czene, K, Darabi, H, Li, J, Dörk, T, Dürst, M, Hillemanns, P, Runnebaum, I, Amant, F, Schrauwen, S, Zhao, H, Lambrechts, D, Depreeuw, J, Dowdy, S, Goode, E, Fridley, B, Winham, S, Njølstad, T, Salvesen, H, Trovik, J, Werner, H, Ashton, K, Otton, G, Proietto, T, Liu, T, Mints, M, Tham, E, Li, M, Yip, S, Wang, J, Bolla, M, Michailidou, K, Wang, Q, Tyrer, J, Dunlop, M, Houlston, R, Palles, C, Hopper, J, Peto, J, Swerdlow, A, Burwinkel, B, Brenner, H, Meindl, A, Brauch, H, Lindblom, A, Chang-Claude, J, Couch, F, Giles, G, Kristensen, V, Cox, A, Cunningham, J, Pharoah, P, Dunning, A, Edwards, S, Easton, D, Tomlinson, I, Spurdle, A

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. 著者: Cheng, T, Thompson, D, Painter, J, O'Mara, T, Gorman, M, Martin, L, Palles, C, Jones, A, Buchanan, D, Ko Win, A, Hopper, J, Jenkins, M, Lindor, N, Newcomb, P, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Giles, G, Pharoah, P, Peto, J, Cox, A, Swerdlow, A, Couch, F, Cunningham, J, Goode, E, Winham, S, Lambrechts, D, Fasching, P, Burwinkel, B, Brenner, H, Brauch, H, Chang-Claude, J, Salvesen, H, Kristensen, V, Darabi, H, Li, J, Liu, T, Lindblom, A, Hall, P, de Polanco, M, Sans, M, Carracedo, A, Castellvi-Bel, S, Rojas-Martinez, A, Aguiar Jnr, S, Teixeira, M, Dunning, A, Dennis, J, Otton, G, Proietto, T, Holliday, E, Attia, J, Ashton, K, Scott, R, McEvoy, M, Dowdy, S, Fridley, B, Werner, H, Trovik, J, Njolstad, T, Tham, E, Mints, M, Runnebaum, I, Hillemanns, P, Dörk, T, Amant, F, Schrauwen, S, Hein, A, Beckmann, M, Ekici, A, Czene, K, Meindl, A, Bolla, M, Michailidou, K, Tyrer, J, Wang, Q, Ahmed, S, Healey, C, Shah, M, Annibali, D, Depreeuw, J, Al-Tassan, N, Harris, R, Meyer, B, Whiffin, N, Hosking, F, Kinnersley, B, Farrington, S, Timofeeva, M, Tenesa, A, Campbell, H, Haile, R, Hodgson, S, Carvajal-Carmona, L, Cheadle, J, Easton, D, Dunlop, M, Houlston, R, Spurdle, A, Tomlinson, I

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer 著者: Shen, H., Fridley, B.L., Song, H.L., Lawrenson, K., Cunningham, J.M., Ramus, S.J., Cicek, M.S., Tyrer, J., Stram, D., Larson, M.C., Kobel, M., Ziogas, A., Zheng, W., Yang, H.P., Wu, A.H., Wozniak, E.L., Woo, Y.L., Winterhoff, B., Wik, E., Whittemore, A.S., Wentzensen, N., Weber, R.P., Vitonis, A.F., Vincent, D., Vierkant, R.A., Vergote, I., Van Den Berg, D., Van Altena, A.M., Tworoger, S.S., Thompson, P.J., Tessier, D.C., Terry, K.L., Teo, S.H., Templeman, C., Stram, D.O., Southey, M.C., Sieh, W., Siddiqui, N., Shvetsov, Y.B., Shu, X.O., Shridhar, V., Wang-Gohrke, S., Severi, G., Schwaab, I., Salvesen, H.B., Rzepecka, I.K., Runnebaum, I.B., Rossing, M.A., Rodriguez-Rodriguez, L., Risch, H.A., Renner, S.P., Poole, E.M., Pike, M.C., Phelan, C.M., Pelttari, L.M., Pejovic, T., Paul, J., Orlow, I., Omar, S.Z., Olson, S.H., Odunsi, K., Nickels, S., Nevanlinna, H., Ness, R.B., Narod, S.A., Nakanishi, T., Moysich, K.B., Monteiro, A.N.A., Moes-Sosnowska, J., Modugno, F., Menon, U., McLaughlin, J.R., McGuire, V., Matsuo, K., Adenan, N.A.M., Massuger, L.F.A.G., Lurie, G., Lundvall, L., Lubinski, J., Lissowska, J., Levine, D.A., Leminen, A., Lee, A.W., Le, N.D., Lambrechts, S., Lambrechts, D., Kupryjanczyk, J., Krakstad, C., Konecny, G.E., Kjaer, S.K., Kiemeney, L.A., Kelemen, L.E., Keeney, G.L., Karlan, B.Y., Karevan, R., Kalli, K.R., Kajiyama, H., Ji, B.T., Jensen, A., Jakubowska, A.

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS 著者: Southey, M, Goldgar, D, Winqvist, R, Pylkäs, K, Couch, F, Tischkowitz, M, Foulkes, W, Dennis, J, Michailidou, K, van Rensburg, E, Heikkinen, T, Nevanlinna, H, Hopper, J, Dörk, T, Claes, K, Reis-Filho, J, Teo, Z, Radice, P, Catucci, I, Peterlongo, P, Tsimiklis, H, Odefrey, F, Dowty, J, Schmidt, M, Broeks, A, Hogervorst, F, Verhoef, S, Carpenter, J, Clarke, C, Scott, R, Fasching, P, Haeberle, L, Ekici, A, Beckmann, M, Peto, J, Dos-Santos-Silva, I, Fletcher, O, Johnson, N, Bolla, M, Sawyer, E, Tomlinson, I, Kerin, M, Miller, N, Marme, F, Burwinkel, B, Yang, R, Guénel, P, Truong, T, Menegaux, F, Sanchez, M, Bojesen, S, Nielsen, S, Flyger, H, Benitez, J, Zamora, M, Perez, J, Menéndez, P, Anton-Culver, H, Neuhausen, S, Ziogas, A, Clarke, C, Brenner, H, Arndt, V, Stegmaier, C, Brauch, H, Brüning, T, Ko, Y, Muranen, T, Aittomäki, K, Blomqvist, C, Bogdanova, N, Antonenkova, N, Lindblom, A, Margolin, S, Mannermaa, A, Kataja, V, Kosma, V, Hartikainen, J, Spurdle, A, Investigators, K, Wauters, E, Smeets, D, Beuselinck, B, Floris, G, Chang-Claude, J, Rudolph, A, Seibold, P, Flesch-Janys, D, Olson, J, Vachon, C, Pankratz, V, McLean, C, Haiman, C, Henderson, B, Schumacher, F, Le Marchand, L, Kristensen, V, Alnæs, G, Zheng, W, Hunter, D, Lindstrom, S, Hankinson, S, Kraft, P, Andrulis, I, Knight, J, Glendon, G, Mulligan, A, Jukkola-Vuorinen, A, Grip, M, Kauppila, S, Devilee, P, Tollenaar, R, Seynaeve, C, Hollestelle, A, Garcia-Closas, M, Figueroa, J, Chanock, S, Lissowska, J, Czene, K, Darabi, H, Eriksson, M, Eccles, D, Rafiq, S, Tapper, W, Gerty, S, Hooning, M, Martens, J, Collée, J, Tilanus-Linthorst, M, Hall, P, Li, J, Brand, J, Humphreys, K, Cox, A, Reed, M, Luccarini, C, Baynes, C, Dunning, A, Hamann, U, Torres, D, Ulmer, H, Rüdiger, T, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Slager, S, Toland, A, Ambrosone, C, Yannoukakos, D, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, González-Neira, A, Pita, G, Alonso, M, Álvarez, N, Herrero, D, Tessier, D, Vincent, D, Bacot, F, Simard, J, Dumont, M, Soucy, P, Eeles, R, Muir, K, Wiklund, F, Gronberg, H, Schleutker, J, Nordestgaard, B, Weischer, M, Travis, R, Neal, D, Donovan, J, Hamdy, F, Khaw, K, Stanford, J, Blot, W, Thibodeau, S, Schaid, D, Kelley, J, Maier, C, Kibel, A, Cybulski, C, Cannon-Albright, L, Butterbach, K, Park, J, Kaneva, R, Batra, J, Teixeira, M, Kote-Jarai, Z, Olama, A, Benlloch, S, Renner, S, Hartmann, A, Hein, A, Ruebner, M, Lambrechts, D, Van Nieuwenhuysen, E, Vergote, I, Lambretchs, S, Doherty, J, Rossing, M, Nickels, S, Eilber, U, Wang-Gohrke, S, Odunsi, K, Sucheston-Campbell, L, Friel, G, Lurie, G, Killeen, J, Wilkens, L, Goodman, M, Runnebaum, I, Hillemanns, P, Pelttari, L, Butzow, R, Modugno, F, Edwards, R, Ness, R, Moysich, K, du Bois, A, Heitz, F, Harter, P, Kommoss, S, Karlan, B, Walsh, C, Lester, J, Jensen, A, Kjaer, S, Høgdall, E, Peissel, B, Bonanni, B, Bernard, L, Goode, E, Fridley, B, Vierkant, R, Cunningham, J, Larson, M, Fogarty, Z, Kalli, K, Liang, D, Lu, K, Hildebrandt, M, Wu, X, Levine, D, Dao, F, Bisogna, M, Berchuck, A, Iversen, E, Marks, J, Akushevich, L, Cramer, D, Schildkraut, J, Terry, K, Poole, E, Stampfer, M, Tworoger, S, Bandera, E, Orlow, I, Olson, S, Bjorge, L, Salvesen, H, van Altena, A, Aben, K, Kiemeney, L, Massuger, L, Pejovic, T, Bean, Y, Brooks-Wilson, A, Kelemen, L, Cook, L, Le, N, Górski, B, Gronwald, J, Menkiszak, J, Høgdall, C, Lundvall, L, Nedergaard, L, Engelholm, S, Dicks, E, Tyrer, J, Campbell, I, McNeish, I, Paul, J, Siddiqui, N, Glasspool, R, Whittemore, A, Rothstein, J, McGuire, V, Sieh, W, Cai, H, Shu, X, Teten, R, Sutphen, R, McLaughlin, J, Narod, S, Phelan, C, Monteiro, A, Fenstermacher, D, Lin, H, Permuth, J, Sellers, T, Chen, Y, Tsai, Y, Chen, Z, Gentry-Maharaj, A, Gayther, S, Ramus, S, Menon, U, Wu, A, Pearce, C, Van Den Berg, D, Pike, M, Dansonka-Mieszkowska, A, Plisiecka-Halasa, J, Moes-Sosnowska, J, Kupryjanczyk, J, Pharoah, P, Song, H, Winship, I, Chenevix-Trench, G, Giles, G, Tavtigian, S, Easton, D, Milne, R