MSI-low, a real phenomenon which varies in frequency among cancer types. door Halford, SE, Sawyer, E, Lambros, M, Gorman, P, Macdonald, N, Talbot, I, Foulkes, W, Gillett, C, Barnes, D, Akslen, L, Lee, K, Jacobs, I, Hanby, A, Ganesan, T, Salvesen, H, Bodmer, W, Tomlinson, I, Roylance, R

A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding door Painter, J, Kaufmann, S, O'Mara, T, Hillman, K, Sivakumaran, H, Darabi, H, Cheng, T, Pearson, J, Kazakoff, S, Waddell, N, Hoivik, E, Goode, E, Scott, R, Tomlinson, I, Dunning, A, Easton, D, French, J, Salvesen, H, Pollock, P, Thompson, D, Spurdle, A, Edwards, S

A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding door Painter, J, Kaufmann, S, O'Mara, T, Hillman, K, Sivakumaran, H, Darabi, H, Cheng, T, Pearson, J, Kazakoff, S, Waddell, N, Hoivik, E, Goode, E, Scott, R, Tomlinson, I, Dunning, A, Easton, D, French, J, Salvesen, H, Pollock, P, Thompson, D, Spurdle, A, Edwards, S

Genome-wide association study identifies a common variant associated with risk of endometrial cancer door Spurdle, AB, Thompson, D, Ahmed, S, Ferguson, K, Healey, C, O'Mara, T, Walker, L, Montgomery, S, Dermitzakis, E, Fahey, P, Montgomery, G, Webb, P, Fasching, P, Beckmann, M, Ekici, AB, Hein, A, Lambrechts, D, Coenegrachts, L, Vergote, I, Amant, F, Salvesen, H, Trovik, J, Njolstad, T, Helland, H, Scott, R

Genome-wide association study identifies a common variant associated with risk of endometrial cancer. door Spurdle, AB, Thompson, D, Ahmed, S, Ferguson, K, Healey, C, O'Mara, T, Walker, L, Montgomery, S, Dermitzakis, E, Fahey, P, Montgomery, G, Webb, P, Fasching, P, Beckmann, M, Ekici, AB, Hein, A, Lambrechts, D, Coenegrachts, L, Vergote, I, Amant, F, Salvesen, H, Trovik, J, Njolstad, T, Helland, H, Scott, R

Genome-wide association study identifies a possible susceptibility locus for endometrial cancer. door Long, J, Zheng, W, Xiang, Y, Lose, F, Thompson, D, Tomlinson, I, Yu, H, Wentzensen, N, Lambrechts, D, Dörk, T, Dubrowinskaja, N, Goodman, M, Salvesen, H, Fasching, P, Scott, R, Delahanty, R, Zheng, Y, O'Mara, T, Healey, C, Hodgson, S, Risch, H, Yang, H, Amant, F, Turmanov, N, Schwake, A

Polymorphisms in inflammation pathway genes and endometrial cancer risk. door Delahanty, R, Xiang, Y, Spurdle, A, Beeghly-Fadiel, A, Long, J, Thompson, D, Tomlinson, I, Yu, H, Lambrechts, D, Dörk, T, Goodman, M, Zheng, Y, Salvesen, H, Bao, P, Amant, F, Beckmann, M, Coenegrachts, L, Coosemans, A, Dubrowinskaja, N, Dunning, A, Runnebaum, I, Easton, D, Ekici, AB, Fasching, P, Halle, M

Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation door Salvesen, H. B., Carter, Scott L., Mannelqvist, M., Dutt, Amit, Getz, Gad, Stefansson, I. M., Raeder, M. B., Sos, M. L., Engelsen, I. B., Trovik, J., Wik, E., Greulich, Heidi, Bo, T. H., Jonassen, I., Thomas, R. K., Zander, T., Garraway, Levi A., Oyan, A. M., Sellers, W. R., Kalland, K. H., Meyerson, Matthew L., Akslen, L. A., Beroukhim, Rameen

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Genetic risk score Mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer. door Painter, J, O'Mara, T, Marquart, L, Webb, P, Attia, J, Medland, S, Cheng, T, Dennis, J, Holliday, E, McEvoy, M, Scott, R, Ahmed, S, Healey, C, Shah, M, Gorman, M, Martin, L, Hodgson, S, Beckmann, M, Ekici, A, Fasching, P, Hein, A, Rübner, M, Czene, K, Darabi, H, Hall, P, Li, J, Dork, T, Durst, M, Hillemanns, P, Runnebaum, I, Amant, F, Annibali, D, Depreeuw, J, Lambrechts, D, Neven, P, Cunningham, J, Dowdy, S, Goode, E, Fridley, B, Winham, S, Njolstad, T, Salvesen, H, Trovik, J, Werner, H, Ashton, K, Otton, G, Proietto, A, Mints, M, Tham, E, Bolla, M, Michailidou, K, Wang, Q, Tyrer, J, Hopper, J, Peto, J, Swerdlow, A, Burwinkel, B, Brenner, H, Meindl, A, Brauch, H, Lindblom, A, Chang-Claude, J, Couch, F, Giles, G, Kristensen, V, Cox, A, Pharoah, P, Tomlinson, I, Dunning, A, Easton, D, Thompson, D, Spurdle, A

Five endometrial cancer risk loci identified through genome-wide association analysis. door Cheng, T, Thompson, D, O'Mara, T, Painter, J, Glubb, D, Flach, S, Lewis, A, French, J, Freeman-Mills, L, Church, D, Gorman, M, Martin, L, Hodgson, S, Webb, P, Attia, J, Holliday, E, McEvoy, M, Scott, R, Henders, A, Martin, N, Montgomery, G, Nyholt, D, Ahmed, S, Healey, C, Shah, M, Dennis, J, Fasching, P, Beckmann, M, Hein, A, Ekici, A, Hall, P, Czene, K, Darabi, H, Li, J, Dörk, T, Dürst, M, Hillemanns, P, Runnebaum, I, Amant, F, Schrauwen, S, Zhao, H, Lambrechts, D, Depreeuw, J, Dowdy, S, Goode, E, Fridley, B, Winham, S, Njølstad, T, Salvesen, H, Trovik, J, Werner, H, Ashton, K, Otton, G, Proietto, T, Liu, T, Mints, M, Tham, E, Li, M, Yip, S, Wang, J, Bolla, M, Michailidou, K, Wang, Q, Tyrer, J, Dunlop, M, Houlston, R, Palles, C, Hopper, J, Peto, J, Swerdlow, A, Burwinkel, B, Brenner, H, Meindl, A, Brauch, H, Lindblom, A, Chang-Claude, J, Couch, F, Giles, G, Kristensen, V, Cox, A, Cunningham, J, Pharoah, P, Dunning, A, Edwards, S, Easton, D, Tomlinson, I, Spurdle, A

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. door Cheng, T, Thompson, D, Painter, J, O'Mara, T, Gorman, M, Martin, L, Palles, C, Jones, A, Buchanan, D, Ko Win, A, Hopper, J, Jenkins, M, Lindor, N, Newcomb, P, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Giles, G, Pharoah, P, Peto, J, Cox, A, Swerdlow, A, Couch, F, Cunningham, J, Goode, E, Winham, S, Lambrechts, D, Fasching, P, Burwinkel, B, Brenner, H, Brauch, H, Chang-Claude, J, Salvesen, H, Kristensen, V, Darabi, H, Li, J, Liu, T, Lindblom, A, Hall, P, de Polanco, M, Sans, M, Carracedo, A, Castellvi-Bel, S, Rojas-Martinez, A, Aguiar Jnr, S, Teixeira, M, Dunning, A, Dennis, J, Otton, G, Proietto, T, Holliday, E, Attia, J, Ashton, K, Scott, R, McEvoy, M, Dowdy, S, Fridley, B, Werner, H, Trovik, J, Njolstad, T, Tham, E, Mints, M, Runnebaum, I, Hillemanns, P, Dörk, T, Amant, F, Schrauwen, S, Hein, A, Beckmann, M, Ekici, A, Czene, K, Meindl, A, Bolla, M, Michailidou, K, Tyrer, J, Wang, Q, Ahmed, S, Healey, C, Shah, M, Annibali, D, Depreeuw, J, Al-Tassan, N, Harris, R, Meyer, B, Whiffin, N, Hosking, F, Kinnersley, B, Farrington, S, Timofeeva, M, Tenesa, A, Campbell, H, Haile, R, Hodgson, S, Carvajal-Carmona, L, Cheadle, J, Easton, D, Dunlop, M, Houlston, R, Spurdle, A, Tomlinson, I

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer door Shen, H., Fridley, B.L., Song, H.L., Lawrenson, K., Cunningham, J.M., Ramus, S.J., Cicek, M.S., Tyrer, J., Stram, D., Larson, M.C., Kobel, M., Ziogas, A., Zheng, W., Yang, H.P., Wu, A.H., Wozniak, E.L., Woo, Y.L., Winterhoff, B., Wik, E., Whittemore, A.S., Wentzensen, N., Weber, R.P., Vitonis, A.F., Vincent, D., Vierkant, R.A., Vergote, I., Van Den Berg, D., Van Altena, A.M., Tworoger, S.S., Thompson, P.J., Tessier, D.C., Terry, K.L., Teo, S.H., Templeman, C., Stram, D.O., Southey, M.C., Sieh, W., Siddiqui, N., Shvetsov, Y.B., Shu, X.O., Shridhar, V., Wang-Gohrke, S., Severi, G., Schwaab, I., Salvesen, H.B., Rzepecka, I.K., Runnebaum, I.B., Rossing, M.A., Rodriguez-Rodriguez, L., Risch, H.A., Renner, S.P., Poole, E.M., Pike, M.C., Phelan, C.M., Pelttari, L.M., Pejovic, T., Paul, J., Orlow, I., Omar, S.Z., Olson, S.H., Odunsi, K., Nickels, S., Nevanlinna, H., Ness, R.B., Narod, S.A., Nakanishi, T., Moysich, K.B., Monteiro, A.N.A., Moes-Sosnowska, J., Modugno, F., Menon, U., McLaughlin, J.R., McGuire, V., Matsuo, K., Adenan, N.A.M., Massuger, L.F.A.G., Lurie, G., Lundvall, L., Lubinski, J., Lissowska, J., Levine, D.A., Leminen, A., Lee, A.W., Le, N.D., Lambrechts, S., Lambrechts, D., Kupryjanczyk, J., Krakstad, C., Konecny, G.E., Kjaer, S.K., Kiemeney, L.A., Kelemen, L.E., Keeney, G.L., Karlan, B.Y., Karevan, R., Kalli, K.R., Kajiyama, H., Ji, B.T., Jensen, A., Jakubowska, A.

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS door Southey, M, Goldgar, D, Winqvist, R, Pylkäs, K, Couch, F, Tischkowitz, M, Foulkes, W, Dennis, J, Michailidou, K, van Rensburg, E, Heikkinen, T, Nevanlinna, H, Hopper, J, Dörk, T, Claes, K, Reis-Filho, J, Teo, Z, Radice, P, Catucci, I, Peterlongo, P, Tsimiklis, H, Odefrey, F, Dowty, J, Schmidt, M, Broeks, A, Hogervorst, F, Verhoef, S, Carpenter, J, Clarke, C, Scott, R, Fasching, P, Haeberle, L, Ekici, A, Beckmann, M, Peto, J, Dos-Santos-Silva, I, Fletcher, O, Johnson, N, Bolla, M, Sawyer, E, Tomlinson, I, Kerin, M, Miller, N, Marme, F, Burwinkel, B, Yang, R, Guénel, P, Truong, T, Menegaux, F, Sanchez, M, Bojesen, S, Nielsen, S, Flyger, H, Benitez, J, Zamora, M, Perez, J, Menéndez, P, Anton-Culver, H, Neuhausen, S, Ziogas, A, Clarke, C, Brenner, H, Arndt, V, Stegmaier, C, Brauch, H, Brüning, T, Ko, Y, Muranen, T, Aittomäki, K, Blomqvist, C, Bogdanova, N, Antonenkova, N, Lindblom, A, Margolin, S, Mannermaa, A, Kataja, V, Kosma, V, Hartikainen, J, Spurdle, A, Investigators, K, Wauters, E, Smeets, D, Beuselinck, B, Floris, G, Chang-Claude, J, Rudolph, A, Seibold, P, Flesch-Janys, D, Olson, J, Vachon, C, Pankratz, V, McLean, C, Haiman, C, Henderson, B, Schumacher, F, Le Marchand, L, Kristensen, V, Alnæs, G, Zheng, W, Hunter, D, Lindstrom, S, Hankinson, S, Kraft, P, Andrulis, I, Knight, J, Glendon, G, Mulligan, A, Jukkola-Vuorinen, A, Grip, M, Kauppila, S, Devilee, P, Tollenaar, R, Seynaeve, C, Hollestelle, A, Garcia-Closas, M, Figueroa, J, Chanock, S, Lissowska, J, Czene, K, Darabi, H, Eriksson, M, Eccles, D, Rafiq, S, Tapper, W, Gerty, S, Hooning, M, Martens, J, Collée, J, Tilanus-Linthorst, M, Hall, P, Li, J, Brand, J, Humphreys, K, Cox, A, Reed, M, Luccarini, C, Baynes, C, Dunning, A, Hamann, U, Torres, D, Ulmer, H, Rüdiger, T, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Slager, S, Toland, A, Ambrosone, C, Yannoukakos, D, Swerdlow, A, Ashworth, A, Orr, N, Jones, M, González-Neira, A, Pita, G, Alonso, M, Álvarez, N, Herrero, D, Tessier, D, Vincent, D, Bacot, F, Simard, J, Dumont, M, Soucy, P, Eeles, R, Muir, K, Wiklund, F, Gronberg, H, Schleutker, J, Nordestgaard, B, Weischer, M, Travis, R, Neal, D, Donovan, J, Hamdy, F, Khaw, K, Stanford, J, Blot, W, Thibodeau, S, Schaid, D, Kelley, J, Maier, C, Kibel, A, Cybulski, C, Cannon-Albright, L, Butterbach, K, Park, J, Kaneva, R, Batra, J, Teixeira, M, Kote-Jarai, Z, Olama, A, Benlloch, S, Renner, S, Hartmann, A, Hein, A, Ruebner, M, Lambrechts, D, Van Nieuwenhuysen, E, Vergote, I, Lambretchs, S, Doherty, J, Rossing, M, Nickels, S, Eilber, U, Wang-Gohrke, S, Odunsi, K, Sucheston-Campbell, L, Friel, G, Lurie, G, Killeen, J, Wilkens, L, Goodman, M, Runnebaum, I, Hillemanns, P, Pelttari, L, Butzow, R, Modugno, F, Edwards, R, Ness, R, Moysich, K, du Bois, A, Heitz, F, Harter, P, Kommoss, S, Karlan, B, Walsh, C, Lester, J, Jensen, A, Kjaer, S, Høgdall, E, Peissel, B, Bonanni, B, Bernard, L, Goode, E, Fridley, B, Vierkant, R, Cunningham, J, Larson, M, Fogarty, Z, Kalli, K, Liang, D, Lu, K, Hildebrandt, M, Wu, X, Levine, D, Dao, F, Bisogna, M, Berchuck, A, Iversen, E, Marks, J, Akushevich, L, Cramer, D, Schildkraut, J, Terry, K, Poole, E, Stampfer, M, Tworoger, S, Bandera, E, Orlow, I, Olson, S, Bjorge, L, Salvesen, H, van Altena, A, Aben, K, Kiemeney, L, Massuger, L, Pejovic, T, Bean, Y, Brooks-Wilson, A, Kelemen, L, Cook, L, Le, N, Górski, B, Gronwald, J, Menkiszak, J, Høgdall, C, Lundvall, L, Nedergaard, L, Engelholm, S, Dicks, E, Tyrer, J, Campbell, I, McNeish, I, Paul, J, Siddiqui, N, Glasspool, R, Whittemore, A, Rothstein, J, McGuire, V, Sieh, W, Cai, H, Shu, X, Teten, R, Sutphen, R, McLaughlin, J, Narod, S, Phelan, C, Monteiro, A, Fenstermacher, D, Lin, H, Permuth, J, Sellers, T, Chen, Y, Tsai, Y, Chen, Z, Gentry-Maharaj, A, Gayther, S, Ramus, S, Menon, U, Wu, A, Pearce, C, Van Den Berg, D, Pike, M, Dansonka-Mieszkowska, A, Plisiecka-Halasa, J, Moes-Sosnowska, J, Kupryjanczyk, J, Pharoah, P, Song, H, Winship, I, Chenevix-Trench, G, Giles, G, Tavtigian, S, Easton, D, Milne, R