Sam Gandy

Samuel E. Gandy, is a neurologist, cell biologist, Alzheimer's disease (AD) researcher and expert in the metabolism of the sticky substance called amyloid that clogs the brain in patients with Alzheimer's. His team discovered the first drugs that could lower the formation of amyloid.

As of 2020, he is Mount Sinai Professor of Alzheimer's Disease Research, professor of neurology and psychiatry, Icahn School of Medicine at Mount Sinai, director, Center for Cognitive Health and NFL Neurological Center Mount Sinai Hospital, visiting principal research fellow, South Australia Health and Medical Research Institute in Adelaide, SA, Australia, and chairman emeritus of the National Medical and Scientific Advisory Council of the Alzheimer's Association. He was also founding director, Farber Institute for the Neurosciences. Provided by Wikipedia
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  1. 1
    News & views: anti-amyloid antibodies and novel emerging approaches to Alzheimer’s disease in 2023

    News & views: anti-amyloid antibodies and novel emerging approaches to Alzheimer’s disease in 2023 by Sam Gandy

    Published 2023-09-01
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  2. 2
    Open peer commentary on “Prescribing anti‐amyloid immunotherapies to treat Alzheimer's disease: Fully informing patient decisions”

    Open peer commentary on “Prescribing anti‐amyloid immunotherapies to treat Alzheimer's disease: Fully informing patient decisions” by Sam Gandy

    Published 2023-10-01
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  3. 3
    The Golgi apparatus: Site for convergence of COVID-19 brain fog and Alzheimer’s disease?

    The Golgi apparatus: Site for convergence of COVID-19 brain fog and Alzheimer’s disease? by Yanzhuang Wang, Sam Gandy

    Published 2022-10-01
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  4. 4
    miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy

    miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy by Sam Gandy, Michelle E. Ehrlich

    Published 2023-09-01
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  5. 5
    [18F]-T807 tauopathy PET imaging in chronic traumatic encephalopathy [v1; ref status: indexed, http://f1000r.es/4fb]

    [18F]-T807 tauopathy PET imaging in chronic traumatic encephalopathy [v1; ref status: indexed, http://f1000r.es/4fb] by Sam Gandy, Steven T. DeKosky

    Published 2014-09-01
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  6. 6
    Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy

    Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy... by Sam Gandy, Michelle E. Ehrlich

    Published 2023-11-01
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  7. 7
    Breaking up (amyloid) is hard to do.

    Breaking up (amyloid) is hard to do. by Sam Gandy, Frank L Heppner

    Published 2005-12-01
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  8. 8
    Talking points for physicians, patients and caregivers considering Aduhelm® infusion and the accelerated pathway for its approval by the FDA

    Talking points for physicians, patients and caregivers considering Aduhelm® infusion and the accelerated pathway for its approval by the FDA by Sam Gandy, David S. Knopman, Mary Sano

    Published 2021-11-01
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  9. 9
    Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2

    Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2 by Jean-Vianney Haure-Mirande, Mickael Audrain, Michelle E. Ehrlich, Sam Gandy

    Published 2022-08-01
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  10. 10
    Food for flower‐visiting insects: Appreciating common native wild flowering plants

    Food for flower‐visiting insects: Appreciating common native wild flowering plants by Veronica R. Wignall, Nicholas J. Balfour, Sam Gandy, Francis L. W. Ratnieks

    Published 2023-08-01
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  11. 11
    Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK.

    Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. by Steve Pedrini, Troy L Carter, George Prendergast, Suzana Petanceska, Michelle E Ehrlich, Sam Gandy

    Published 2005-01-01
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  12. 12
    The potential synergistic effects between psychedelic administration and nature contact for the improvement of mental health

    The potential synergistic effects between psychedelic administration and nature contact for the improvement of mental health by Sam Gandy, Matthias Forstmann, Robin Lester Carhart-Harris, Christopher Timmermann, David Luke, Rosalind Watts

    Published 2020-12-01
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  13. 13
    Rapid doubling of Alzheimer’s amyloid-β40 and 42 levels in brains of mice exposed to a nickel nanoparticle model of air pollution [v1; ref status: indexed, http://f1000r.es/T5Rxeo]

    Rapid doubling of Alzheimer’s amyloid-β40 and 42 levels in brains of mice exposed to a nickel nanoparticle model of air pollution [v1; ref status: indexed, http://f1000r.es/T5Rxeo]... by Soong Ho Kim, Elysse M Knight, Eric L Saunders, Azita K Cuevas, Marusia Popovech, Lung-Chi Chen, Sam Gandy

    Published 2012-12-01
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  14. 14
    Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP.

    Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. by Yoshitake Sano, Tadashi Nakaya, Steve Pedrini, Shizu Takeda, Kanae Iijima-Ando, Koichi Iijima, Paul M Mathews, Shigeyoshi Itohara, Sam Gandy, Toshiharu Suzuki

    Published 2006-12-01
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  15. 15
    Pathway Analysis for Plasma β-Amyloid, Tau and Neurofilament Light (ATN) in World Trade Center Responders at Midlife

    Pathway Analysis for Plasma β-Amyloid, Tau and Neurofilament Light (ATN) in World Trade Center Responders at Midlife by Minos Kritikos, Sean A. P. Clouston, Erica D. Diminich, Yael Deri, Xiaohua Yang, Melissa Carr, Sam Gandy, Mary Sano, Evelyn J. Bromet, Benjamin J. Luft

    Published 2020-04-01
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  16. 16
    iPSC-derived familial Alzheimer’s PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling

    iPSC-derived familial Alzheimer’s PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling by Cesar L. Moreno, Lucio Della Guardia, Valeria Shnyder, Maitane Ortiz-Virumbrales, Ilya Kruglikov, Bin Zhang, Eric E. Schadt, Rudolph E. Tanzi, Scott Noggle, Christoph Buettner, Sam Gandy

    Published 2018-06-01
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  17. 17
    Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females

    Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females by Allen L. Pan, Mickael Audrain, Emmy Sakakibara, Rajeev Joshi, Xiaodong Zhu, Qian Wang, Minghui Wang, Noam D. Beckmann, Eric E. Schadt, Sam Gandy, Bin Zhang, Michelle E. Ehrlich, Stephen R. Salton

    Published 2022-12-01
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  18. 18
    Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

    Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models by Michiko Sekiya, Minghui Wang, Naoki Fujisaki, Yasufumi Sakakibara, Xiuming Quan, Michelle E. Ehrlich, Philip L. De Jager, David A. Bennett, Eric E. Schadt, Sam Gandy, Kanae Ando, Bin Zhang, Koichi M. Iijima

    Published 2018-03-01
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  19. 19
    Incidence of mild cognitive impairment in World Trade Center responders: Long‐term consequences of re‐experiencing the events on 9/11/2001

    Incidence of mild cognitive impairment in World Trade Center responders: Long‐term consequences of re‐experiencing the events on 9/11/2001 by Sean A.P. Clouston, Erica D. Diminich, Roman Kotov, Robert H. Pietrzak, Marcus Richards, Avron Spiro III, Yael Deri, Melissa Carr, Xiaohua Yang, Sam Gandy, Mary Sano, Evelyn J. Bromet, Benjamin J. Luft

    Published 2019-12-01
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  20. 20
    Reduced cerebellar cortical thickness in World Trade Center responders with cognitive impairment

    Reduced cerebellar cortical thickness in World Trade Center responders with cognitive impairment by Sean A. P. Clouston, Minos Kritikos, Chuan Huang, Pei-Fen Kuan, Paul Vaska, Alison C. Pellecchia, Stephanie Santiago-Michels, Melissa A. Carr, Sam Gandy, Mary Sano, Evelyn J. Bromet, Roberto G. Lucchini, Benjamin J. Luft

    Published 2022-03-01
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