An explanatory case report about critical differences of ‘inability to work’ in Italian welfare and social security systems by Michele Sammicheli, Marcella Scaglione

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Alum/Toll-Like Receptor 7 Adjuvant Enhances the Expansion of Memory B Cell Compartment Within the Draining Lymph Node by Hoa Thi My Vo, Barbara Christiane Baudner, Stefano Sammicheli, Stefano Sammicheli, Matteo Iannacone, Matteo Iannacone, Ugo D’Oro, Diego Piccioli

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Dataset of antibody variable region sequence features inferred from a respiratory syncytial virus fusion protein-specific B cell receptor repertoire induced by natural infection of... by Gerald Schneikart, Simona Tavarini, Chiara Sammicheli, Giulia Torricelli, Silvia Guidotti, Ugo D'Oro, Oretta Finco, Monia Bardelli

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IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway. by Stefano Sammicheli, Vu Phuong Linh Dang, Nicolas Ruffin, Hong Thang Pham, Rebecka Lantto, Nancy Vivar, Francesca Chiodi, Bence Rethi

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Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model. by Floriana Cremasco, Elena Menietti, Dario Speziale, Johannes Sam, Stefano Sammicheli, Marine Richard, Ahmet Varol, Christian Klein, Pablo Umana, Marina Bacac, Sara Colombetti, Mario Perro

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Incidence of lower limb deep vein thrombosis in patients with COVID-19 pneumonia through different waves of SARS-CoV-2 pandemic: A multicenter prospective study. by Filippo Pieralli, Fulvio Pomero, Lorenzo Corbo, Alberto Fortini, Giulia Guazzini, Lisa Lastraioli, Fabio Luise, Antonio Mancini, Lucia Maddaluni, Alessandro Milia, Lucia Sammicheli, Filippo Mani, Rossella Marcucci

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Single-Cell Analysis of Antigen-Specific CD8+ T-Cell Transcripts Reveals Profiles Specific to mRNA or Adjuvanted Protein Vaccines by Trine Sundebo Meldgaard, Trine Sundebo Meldgaard, Fabiola Blengio, Denise Maffione, Chiara Sammicheli, Simona Tavarini, Sandra Nuti, Sandra Nuti, Roland Kratzer, Duccio Medini, Emilio Siena, Sylvie Bertholet, Sylvie Bertholet

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Ex vivo analysis of human memory B lymphocytes specific for A and B influenza hemagglutinin by polychromatic flow-cytometry. by Monia Bardelli, Liliana Alleri, Francesca Angiolini, Francesca Buricchi, Simona Tavarini, Chiara Sammicheli, Sandra Nuti, Elena Degl'Innocenti, Isabelle Isnardi, Elena Fragapane, Giuseppe Del Giudice, Flora Castellino, Grazia Galli

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Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA by Serena Tondi, Serena Tondi, Bruna Clemente, Carmen Esposito, Chiara Sammicheli, Simona Tavarini, Laura B. Martin, Omar Rossi, Francesca Micoli, Erika Bartolini, Michela Brazzoli, Cristina Ulivieri, Christoph J. Blohmke, Francesca Schiavetti

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The respiratory syncytial virus (RSV) prefusion F‐protein functional antibody repertoire in adult healthy donors by Emanuele Andreano, Ida Paciello, Monia Bardelli, Simona Tavarini, Chiara Sammicheli, Elisabetta Frigimelica, Silvia Guidotti, Giulia Torricelli, Marco Biancucci, Ugo D’Oro, Sumana Chandramouli, Matthew J Bottomley, Rino Rappuoli, Oretta Finco, Francesca Buricchi

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Incidence of deep vein thrombosis through an ultrasound surveillance protocol in patients with COVID-19 pneumonia in non-ICU setting: A multicenter prospective study. by Filippo Pieralli, Fulvio Pomero, Margherita Giampieri, Rossella Marcucci, Domenico Prisco, Fabio Luise, Antonio Mancini, Alessandro Milia, Lucia Sammicheli, Irene Tassinari, Francesca Caldi, Francesca Innocenti, Antonio Faraone, Chiara Beltrame, Riccardo Pini, Andrea Ungar, Alberto Fortini

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Vaccination With a FAT1-Derived B Cell Epitope Combined With Tumor-Specific B and T Cell Epitopes Elicits Additive Protection in Cancer Mouse Models by Alberto Grandi, Laura Fantappiè, Carmela Irene, Silvia Valensin, Michele Tomasi, Simone Stupia, Riccardo Corbellari, Elena Caproni, Ilaria Zanella, Samine J. Isaac, Luisa Ganfini, Luca Frattini, Enrico König, Assunta Gagliardi, Simona Tavarini, Chiara Sammicheli, Matteo Parri, Guido Grandi

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Optimized fluorescent labeling to identify memory B cells specific for Neisseria meningitidis serogroup B vaccine antigens ex vivo by Nair, Nitya, Buti, Ludovico, Faenzi, Elisa, Buricchi, Francesca, Nuti, Sandra, Sammicheli, Chiara, Tavarini, Simona, Popp, Maximilian W.L., Ploegh, Hidde, Berti, Francesco, Pizza, Mariagrazia, Castellino, Flora, Finco, Oretta, Rappuoli, Rino, Del Giudice, Giuseppe, Galli, Grazia, Bardelli, Monia

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Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination? by Jonah Clegg, Jonah Clegg, Malgorzata E. Mnich, Malgorzata E. Mnich, Alberto Carignano, Giovanni Cova, Simona Tavarini, Chiara Sammicheli, Bruna Clemente, Megan Smith, Megan Smith, Emilio Siena, Monia Bardelli, Michela Brazzoli, Fabio Bagnoli, Rachel M. McLoughlin, Elisabetta Soldaini

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Bisphosphonates Target B Cells to Enhance Humoral Immune Responses by Elena Tonti, Nereida Jiménez de Oya, Gabriele Galliverti, E. Ashley Moseman, Pietro Di Lucia, Angelo Amabile, Stefano Sammicheli, Marco De Giovanni, Laura Sironi, Nicolas Chevrier, Giovanni Sitia, Luigi Gennari, Luca G. Guidotti, Ulrich H. von Andrian, Matteo Iannacone

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P871: ISB 1442, A FIRST-IN-CLASS CD38 AND CD47 BISPECIFIC ANTIBODY INNATE CELL MODULATOR FOR THE TREATMENT OF CD38 POSITIVE HEMATOLOGICAL MALIGNANCIES by C. Grandclement, C. Estoppey, E. Dheilly, M. Panagopoulou, E. Martini, V. Labanca, S. De Angelis, J. Frei, A. Drake, A. Rubod, G. Gudi, V. Udupa, J. Koch Olsen, R. Giovannini, M. A. Doucey, E. Feldman, C. Konto, A. Srivastava, M. Perro, S. Sammicheli

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Biparatopic binding of ISB 1442 to CD38 in trans enables increased cell antibody density and increased avidity by Jeremy Loyau, Thierry Monney, Marco Montefiori, Fedir Bokhovchuk, Jeremy Streuli, Matthew Blackburn, Arnaud Goepfert, Lydia N. Caro, Samitabh Chakraborti, Stefania De Angelis, Camille Grandclément, Stanislas Blein, M. Lamine Mbow, Ankita Srivastava, Mario Perro, Stefano Sammicheli, Eugene A. Zhukovsky, Michael Dyson, Cyrille Dreyfus

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One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A. by Francesca Mancini, Elisabetta Monaci, Giuseppe Lofano, Antonina Torre, Marta Bacconi, Simona Tavarini, Chiara Sammicheli, Letizia Arcidiacono, Bruno Galletti, Donatello Laera, Michele Pallaoro, Giovanna Tuscano, Maria Rita Fontana, Giuliano Bensi, Guido Grandi, Silvia Rossi-Paccani, Sandra Nuti, Rino Rappuoli, Ennio De Gregorio, Fabio Bagnoli, Elisabetta Soldaini, Sylvie Bertholet

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Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma by Grandclément, C, Estoppey, C, Dheilly, E, Panagopoulou, M, Monney, T, Dreyfus, C, Loyau, J, Labanca, V, Drake, A, De Angelis, S, Rubod, A, Frei, J, Caro, LN, Blein, S, Martini, E, Chimen, M, Matthes, T, Kaya, Z, Edwards, CM, Edwards, JR, Menoret, E, Kervoelen, C, Pellat-Deceunynck, C, Moreau, P, Mbow, ML, Srivastava, A, Dyson, MR, Zhukovsky, EA, Perro, M, Sammicheli, S

Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma by C. Grandclément, C. Estoppey, E. Dheilly, M. Panagopoulou, T. Monney, C. Dreyfus, J. Loyau, V. Labanca, A. Drake, S. De Angelis, A. Rubod, J. Frei, L. N. Caro, S. Blein, E. Martini, M. Chimen, T. Matthes, Z. Kaya, C. M. Edwards, J. R. Edwards, E. Menoret, C. Kervoelen, C. Pellat-Deceunynck, P. Moreau, M. L. Mbow, A. Srivastava, M. R. Dyson, E. A. Zhukovsky, M. Perro, S. Sammicheli

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