An Integrated Genomics and Clinical Resource for Data-Driven Health Services Policy and Practice Decisionmaking by Mary Mcbride, Samuel Aparicio, John Spinelli, Scott Tyldesley

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Ubiquitin-mediated DNA damage response is synthetic lethal with G-quadruplex stabilizer CX-5461 by Tehmina Masud, Charles Soong, Hong Xu, Justina Biele, Saelin Bjornson, Steven McKinney, Samuel Aparicio

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Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence by Momoko Ohori, Yusuke Nakayama, Mari Ogasawara-Shimizu, Hiroyoshi Toyoshiba, Atsushi Nakanishi, Samuel Aparicio, Shinsuke Araki

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Solution NMR structure and histone binding of the PHD domain of human MLL5. by Alexander Lemak, Adelinda Yee, Hong Wu, Damian Yap, Hong Zeng, Ludmila Dombrovski, Scott Houliston, Samuel Aparicio, Cheryl H Arrowsmith

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Tumores Oncocíticos da Supra-Renal by Andreia Capela, Aurélia Martinho, Fernanda Paixão Duarte, Hermano Garcia, Francisco Rocha Pires, Rita Theias Manso, Samuel Aparício, Ana Maria Costa

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Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics by Seong-Hwan Jun, Hosein Toosi, Jeff Mold, Camilla Engblom, Xinsong Chen, Ciara O’Flanagan, Michael Hagemann-Jensen, Rickard Sandberg, Samuel Aparicio, Johan Hartman, Andrew Roth, Jens Lagergren

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Expansion microscopy using a single anchor molecule for high-yield multiplexed imaging of proteins and RNAs by Yi Cui, Gaojie Yang, Daniel R. Goodwin, Ciara H. O’Flanagan, Anubhav Sinha, Chi Zhang, Kristina E. Kitko, Tay Won Shin, Demian Park, Samuel Aparicio, Edward S. Boyden

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A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation. by Nathan V Lee, Maruja E Lira, Adam Pavlicek, Jingjing Ye, Dana Buckman, Shubha Bagrodia, Sreesha P Srinivasa, Yongjun Zhao, Samuel Aparicio, Paul A Rejto, James G Christensen, Keith A Ching

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Correction: A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation. by Nathan V. Lee, Maruja E. Lira, Adam Pavlicek, Jingjing Ye, Dana Buckman, Shubha Bagrodia, Sreesha P. Srinivasa, Yongjun Zhao, Samuel Aparicio, Paul A. Rejto, James G. Christensen, Keith A. Ching

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High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations by Tony Hui, Qi Cao, Joanna Wegrzyn-Woltosz, Kieran O'Neill, Colin A. Hammond, David J.H.F. Knapp, Emma Laks, Michelle Moksa, Samuel Aparicio, Connie J. Eaves, Aly Karsan, Martin Hirst

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Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector by Nicholas Ceglia, Zachary Sethna, Samuel S. Freeman, Florian Uhlitz, Viktoria Bojilova, Nicole Rusk, Bharat Burman, Andrew Chow, Sohrab Salehi, Farhia Kabeer, Samuel Aparicio, Benjamin D. Greenbaum, Sohrab P. Shah, Andrew McPherson

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Atrophin controls developmental signaling pathways via interactions with Trithorax-like by Kelvin Yeung, Ann Boija, Edvin Karlsson, Per-Henrik Holmqvist, Yonit Tsatskis, Ilaria Nisoli, Damian Yap, Alireza Lorzadeh, Michelle Moksa, Martin Hirst, Samuel Aparicio, Manolis Fanto, Per Stenberg, Mattias Mannervik, Helen McNeill

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Expansion microscopy using a single anchor molecule for high-yield multiplexed imaging of proteins and RNAs. by Yi Cui, Gaojie Yang, Daniel R Goodwin, Ciara H O'Flanagan, Anubhav Sinha, Chi Zhang, Kristina E Kitko, Tay Won Shin, Demian Park, Samuel Aparicio, CRUK IMAXT Grand Challenge Consortium, Edward S Boyden

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Mll5 is required for normal spermatogenesis. by Damian B Yap, David C Walker, Leah M Prentice, Steven McKinney, Gulisa Turashvili, Katrin Mooslehner-Allen, Teresa Ruiz de Algara, John Fee, Xavier d'Anglemont de Tassigny, William H Colledge, Samuel Aparicio

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Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell... by Ada W Y Leung, Stacy S Hung, Ian Backstrom, Daniel Ricaurte, Brian Kwok, Steven Poon, Steven McKinney, Romulo Segovia, Jenna Rawji, Mohammed A Qadir, Samuel Aparicio, Peter C Stirling, Christian Steidl, Marcel B Bally

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clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers by Kieran R. Campbell, Adi Steif, Emma Laks, Hans Zahn, Daniel Lai, Andrew McPherson, Hossein Farahani, Farhia Kabeer, Ciara O’Flanagan, Justina Biele, Jazmine Brimhall, Beixi Wang, Pascale Walters, IMAXT Consortium, Alexandre Bouchard-Côté, Samuel Aparicio, Sohrab P. Shah

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Epiclomal: Probabilistic clustering of sparse single-cell DNA methylation data. by Camila P E de Souza, Mirela Andronescu, Tehmina Masud, Farhia Kabeer, Justina Biele, Emma Laks, Daniel Lai, Patricia Ye, Jazmine Brimhall, Beixi Wang, Edmund Su, Tony Hui, Qi Cao, Marcus Wong, Michelle Moksa, Richard A Moore, Martin Hirst, Samuel Aparicio, Sohrab P Shah

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Circulating tumour mutation detection in triple-negative breast cancer as an adjunct to tissue response assessment by Elena Zaikova, Brian Y. C. Cheng, Viviana Cerda, Esther Kong, Daniel Lai, Amy Lum, Cherie Bates, Wendie den Brok, Takako Kono, Sylvie Bourque, Angela Chan, Xioalan Feng, David Fenton, Anagha Gurjal, Nathalie Levasseur, Caroline Lohrisch, Sarah Roberts, Tamara Shenkier, Christine Simmons, Sara Taylor, Diego Villa, Ruth Miller, Rosalia Aguirre-Hernandez, Samuel Aparicio, Karen Gelmon

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Accurate determination of CRISPR-mediated gene fitness in transplantable tumours by Peter Eirew, Ciara O’Flanagan, Jerome Ting, Sohrab Salehi, Jazmine Brimhall, Beixi Wang, Justina Biele, Teresa Algara, So Ra Lee, Corey Hoang, Damian Yap, Steven McKinney, Cherie Bates, Esther Kong, Daniel Lai, Sean Beatty, Mirela Andronescu, Elena Zaikova, Tyler Funnell, Nicholas Ceglia, Stephen Chia, Karen Gelmon, Colin Mar, Sohrab Shah, Andrew Roth, Alexandre Bouchard-Côté, Samuel Aparicio

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Improving breast cancer survival analysis through competition-based multidimensional modeling. by Erhan Bilal, Janusz Dutkowski, Justin Guinney, In Sock Jang, Benjamin A Logsdon, Gaurav Pandey, Benjamin A Sauerwine, Yishai Shimoni, Hans Kristian Moen Vollan, Brigham H Mecham, Oscar M Rueda, Jorg Tost, Christina Curtis, Mariano J Alvarez, Vessela N Kristensen, Samuel Aparicio, Anne-Lise Børresen-Dale, Carlos Caldas, Andrea Califano, Stephen H Friend, Trey Ideker, Eric E Schadt, Gustavo A Stolovitzky, Adam A Margolin

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