Editorial for Special Issue “Advances in the Pathogenesis and Treatment of Immune-Mediated Inflammatory Diseases” by Jan Piet van Hamburg, Sander W. Tas

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Editorial: Non-canonical NF-κB signaling in immune-mediated inflammatory diseases and malignancies by Sander W. Tas, Sander W. Tas, Vanessa L. Bryant, Vanessa L. Bryant, Vanessa L. Bryant, Matthew C. Cook, Matthew C. Cook

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B Lineage Cells in ANCA-Associated Vasculitis by Ana Merino-Vico, Jan Piet van Hamburg, Sander W. Tas

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Various Tastes of Sugar: The Potential of Glycosylation in Targeting and Modulating Human Immunity via C-Type Lectin Receptors by Stefanie Busold, Noémi A. Nagy, Sander W. Tas, Sander W. Tas, Ronald van Ree, Ronald van Ree, Esther C. de Jong, Teunis B. H. Geijtenbeek

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Symptomatic creatine phosphokinase elevation in a Crohn's disease patient caused by upadacitinib by Anna Schuitema, Suzanne I. Anjie, Agnies M. vanEeghen, Sander W. Tas, Mark Löwenberg

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Toll-like receptor 4 and Syk kinase shape dendritic cell-induced immune activation to major house dust mite allergens by Stefanie Busold, Stefanie Busold, Jaap H. Akkerdaas, Jaap H. Akkerdaas, Esther M. Zijlstra-Willems, Esther M. Zijlstra-Willems, Kees van der Graaf, Sander W. Tas, Sander W. Tas, Sander W. Tas, Esther C. de Jong, Esther C. de Jong, Ronald van Ree, Ronald van Ree, Ronald van Ree, Teunis B. H. Geijtenbeek, Teunis B. H. Geijtenbeek

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In rheumatoid arthritis inflamed joints share dominant patient-specific B-cell clones by Anne Musters, Giulia Balzaretti, Giulia Balzaretti, Barbera D. C. van Schaik, Aldo Jongejan, Linda van der Weele, Linda van der Weele, Sander W. Tas, Sander W. Tas, Antoine H. C. van Kampen, Niek de Vries, Niek de Vries

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A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages by Eva M. L. Philippon, Eva M. L. Philippon, Lisanne J. E. van Rooijen, Lisanne J. E. van Rooijen, Fatemeh Khodadust, Jan Piet van Hamburg, Jan Piet van Hamburg, Conny J. van der Laken, Sander W. Tas, Sander W. Tas

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Liposomes loaded with vitamin D3 induce regulatory circuits in human dendritic cells by Noémi Anna Nagy, Fernando Lozano Vigario, Rinske Sparrius, Toni M. M. van Capel, Ronald van Ree, Ronald van Ree, Sander W. Tas, Sander W. Tas, I. Jolanda M. de Vries, Teunis B. H. Geijtenbeek, Bram Slütter, Esther C. de Jong, for the DC4Balance consortium

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Discovery of innovative therapies for rare immune-mediated inflammatory diseases via off-label prescription of biologics: the case of IL-6 receptor blockade in Castleman’s disease... by Anne eMusters, Amira M.N. Assaf, Danielle M. Gerlag, Paul P. Tak, Paul P. Tak, Paul P. Tak, Sander W. Tas

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Systematic Review: Targeted Molecular Imaging of Angiogenesis and Its Mediators in Rheumatoid Arthritis by Fatemeh Khodadust, Aiarpi Ezdoglian, Maarten M. Steinz, Judy R. van Beijnum, Gerben J. C. Zwezerijnen, Gerrit Jansen, Sander W. Tas, Conny J. van der Laken

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Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens by Joannah R. Fergusson, Michael D. Morgan, Melanie Bruchard, Leonie Huitema, Leonie Huitema, Balthasar A. Heesters, Vincent van Unen, Jan Piet van Hamburg, Jan Piet van Hamburg, Nicole N. van der Wel, Daisy Picavet, Frits Koning, Sander W. Tas, Sander W. Tas, Mark S. Anderson, John C. Marioni, John C. Marioni, John C. Marioni, Georg A. Holländer, Hergen Spits

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Efficient Neutrophil Activation Requires Two Simultaneous Activating Stimuli by Sanne Mol, Florianne M. J. Hafkamp, Laura Varela, Neena Simkhada, Esther W. Taanman-Kueter, Sander W. Tas, Marca H. M. Wauben, Tom Groot Kormelink, Esther C. de Jong

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Splenic Architecture and Function Requires Tight Control of Transmembrane TNF Expression by Kim C. M. Jeucken, Merlijn H. Kaaij, Jasper Rip, Charlotte C. N. van Rooijen, Yik Y. Kan, Odilia B. J. Corneth, Jan Piet van Hamburg, Sander W. Tas

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Differential Contribution of NF-κB Signaling Pathways to CD4+ Memory T Cell Induced Activation of Endothelial Cells by Kim C. M. Jeucken, Kim C. M. Jeucken, Charlotte C. N. van Rooijen, Charlotte C. N. van Rooijen, Yik Y. Kan, Yik Y. Kan, Lotte A. Kocken, Lotte A. Kocken, Aldo Jongejan, Abraham C. I. van Steen, Jaap D. van Buul, Jaap D. van Buul, Henric K. Olsson, Jan Piet van Hamburg, Jan Piet van Hamburg, Sander W. Tas, Sander W. Tas

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Ultrasound-guided lymph node biopsy sampling to study the immunopathogenesis of rheumatoid arthritis: a well-tolerated valuable research tool by Renée H. Fiechter, Janne W. Bolt, Marleen G. H. van de Sande, Caroline J. Aalbers, Robert B. M. Landewé, Mario Maas, Sander W. Tas, Lisa G. M. van Baarsen

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O33 Longitudinal assessment of biomarkers in NOBILITY, a randomized, phase II clinical trial of obinutuzumab for treatment of proliferative lupus nephritis by Richard A Furie, Sander W Tas, Edward M Vital, Ana Malvar, Thomas Schindler, Harini Raghu, Cary M Looney, Jorge A Ross Terres, Veronica G Anania, Ashley Mao, Elsa Martins

Hyaluronic Acid in Synovial Fluid Prevents Neutrophil Activation in Spondyloarthritis by Sanne Mol, Esther W. M. Taanman-Kueter, Baltus A. van der Steen, Tom Groot Kormelink, Marleen G. H. van de Sande, Sander W. Tas, Marca H. M. Wauben, Esther C. de Jong

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Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis by Ihsan Hammoura, Renee H. Fiechter, Shaughn H. Bryant, Susan Westmoreland, Gillian Kingsbury, Wendy Waegell, Sander W. Tas, Dominique L. Baeten, Marleen G. H. van de Sande, Melissa N. van Tok, Leonie M. van Duivenvoorde

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Patient-perspective and feasibility of home finger-prick testing to complement and facilitate large-scale research in rheumatology by Sander W Tas, Michael T Nurmohamed, Gertjan Wolbink, Theo Rispens, Martijn Gerritsen, Erik H Vogelzang, Laura Boekel, Femke Hooijberg, Yaëlle R Besten, Maureen Leeuw, Sadaf Atiqi, Maurice Steenhuis, Sofie Keijzer, Jim Keijser, Floris C Loeff

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