Germline DNA damage response gene mutations as predictive biomarkers of immune checkpoint inhibitor efficacy by Michael J. Dennis, Michael J. Dennis, Sophia Bylsma, Lisa Madlensky, Lisa Madlensky, Meghana S. Pagadala, Hannah Carter, Hannah Carter, Sandip P. Patel, Sandip P. Patel

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756 First-in-human, open-label, multicenter, phase 1 clinical study to evaluate safety, tolerability, pharmacokinetics and pharmacodynamics of anti Siglec-15 PYX-106 in subjects wi... by Bin Zhang, Marsha Crochiere, Anthony W Tolcher, Randy Sweis, Kartik Sehgal, Michael S Gordon, Shui He, Jason Henry, Alexander I Spira, Shiraj Sen, Sandip P Patel, Sondra Smyrnios, Dipali Unadkat

Genomic Immune Evasion: Diagnostic and Therapeutic Opportunities in Head and Neck Squamous Cell Carcinomas by Kedar Kirtane, Maie St. John, Harry Fuentes-Bayne, Sandip P. Patel, Armen Mardiros, Han Xu, Eric W. Ng, William Y. Go, Deborah J. Wong, John B. Sunwoo, John S. Welch

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Utomilumab in Patients With Immune Checkpoint Inhibitor-Refractory Melanoma and Non-Small-Cell Lung Cancer by David S. Hong, Ajay K. Gopal, Alexander N. Shoushtari, Sandip P. Patel, Aiwu R. He, Toshihiko Doi, Suresh S. Ramalingam, Amita Patnaik, Shahneen Sandhu, Ying Chen, Craig B. Davis, Timothy S. Fisher, Bo Huang, Kolette D. Fly, Antoni Ribas

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Phase 1/2 study of monalizumab plus durvalumab in patients with advanced solid tumors by Jarushka Naidoo, Maria L Ascierto, Matthew D Hellmann, Ding Wang, Susana Banerjee, Mayukh Das, Panagiotis Kourtesis, Jennifer R Diamond, Teresa Alonso-Gordoa, Sandip P Patel, Nathan E Standifer, Doug C Palmer, Lin-Yang Cheng, Benedito A Carneiro

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708 A phase 1/2 study of rinatabart sesutecan (PRO1184), a novel folate receptor alpha-directed antibody-drug conjugate, in patients with locally advanced and/or metastatic solid t... by Jing Wang, Jian Zhang, Jun Zhang, Ning Li, Xiaohua Wu, Elizabeth Lee, Naomi Hunder, Ying Cheng, Debra L Richardson, Erika Hamilton, Lin Wu, Ira Winer, Ian Anderson, Gottfried Konecny, Douglas Orr, Oladapo Yeku, Sandip P Patel, Sharon Ma, Eric Song, Justin A Call, Lian Lu

Multicenter phase II trial (SWOG S1609, cohort 51) of ipilimumab and nivolumab in metastatic or unresectable angiosarcoma: a substudy of dual anti-CTLA-4 and anti-PD-1 blockade in... by Howard Streicher, Elad Sharon, Razelle Kurzrock, Young Kwang Chae, Megan Othus, Edward Mayerson, Melissa Plets, Charles Blanke, Ashish Sangal, Benjamin Powers, Chung-Tsen Hsueh, Rashmi Chugh, Suresh Nair, Mark Agulnik, G Thomas Budd, Michael J Wagner, Sandip P Patel, Chris Ryan, Adrienne I Victor, Kirsten M Leu

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1043 Intratumoral mRNA IL-12 can induce a dose dependent immunostimulatory effect within tumor microenvironment in patients with advanced solid tumors by Vivek Subbiah, Dmitriy Zamarin, Omid Hamid, Igor Feldman, Thomas Marron, Yuling Wu, Inderjit Mehmi, Michael Abadier, Analia Azaro, Anthony El-Khoueiry, Eduardo Castañón Álvarez, Jacky Chow, Praveen Aanur, Khanh Do, Vasudha Sehgal, Sandip P Patel, Benedito Carneiro, Linh Van, Nicholas Durham, Xiaoru Chen, Paula G Fraenkel, Arjun Oberoi

The Role of Chemotherapy Plus Immune Checkpoint Inhibitors in Oncogenic-Driven NSCLC: A University of California Lung Cancer Consortium Retrospective Study by David J. Benjamin, MD, Shuai Chen, PhD, Joanna B. Eldredge, MD, Shiruyeh Schokrpur, MD, Debory Li, Zhikuan Quan, MS, Jason W. Chan, MD, Amy L. Cummings, MD, Megan E. Daly, MD, Jonathan W. Goldman, MD, Matthew A. Gubens, MD, Jeremy P. Harris, MD, Mark W. Onaitis, MD, Viola W. Zhu, MD, PhD, Sandip P. Patel, MD, Karen Kelly, MD

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634 EVEREST-1: A seamless phase 1/2 study of CEA logic-gated Tmod CAR T-cell therapy (A2B530) in patients with solid tumors associated with CEA expression also exhibiting HLA loss... by Sarah Nikiforow, Yi Lin, Marcela Maus, Armen Mardiros, Frederick L Locke, Scott Kopetz, Matthew Frigault, David Maloney, Jeffrey Ward, Jennifer Specht, Edward Garon, Diane M Simeone, John Welch, Kedar Kirtane, Marwan Fakih, Julian Molina, Kirstin Liechty, Ariane Lozac’hmeur, J Randolph Hecht, Caleb Smith, Salman R Punekar, Theodore Welling, M Pia Morelli, Patrick M Grierson, Sandip P Patel, Wen-Kai Weng, Tomislav Dragovich, Judy Vong, William Y Go, Eric W Ng

590 Clinical outcomes and translational analysis of DART S1609: the thyroid cancer cohort; PD-1+ PD-L1+ TIL correlated with favorable survival by Jianhua Zhang, Hong Chen, Cara Haymaker, Elad Sharon, Razelle Kurzrock, Young Kwang Chae, Jiexin Zhang, Jack Lee, Jianjun Zhang, Ignacio Wistuba, Megan Othus, Sarah Fenton, Cristina Rodriguez, Adedayo Onitilo, Ahmad Mattour, Igor Rybkin, Christine McLeod, Helen Chen, Christopher Ryan, Melissa Plets, Charles Blanke, Gheath Al-Atrash, Rajyalakshmi Luthra, Hye Sung Kim, Dzifa Y Duose, Liam Il-Young Chung, Sandip P Patel, Yichen Lu, Edwin Roger Parra, Lorena Isabel Gomez Bolanos, Caddie Laberiano Fernandez, Luisa Solis Soto, Ganiraju Manyam, Gabby Lopez