Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses by Meng, JX, Zhang, Y, Saman, D, Haider, AM, De, S, Sang, JC, Brown, K, Jiang, K, Humphrey, J, Julian, L, Hidari, E, Lee, SF, Balmus, G, Floto, RA, Bryant, CE, Benesch, JLP, Ye, Y, Klenerman, D