Better translation via collaboration: the MRC National Mouse Genetics Network od Sansom, O, Wells, S, Kent, D, Wood, A, Pitceathly, RDS, Isles, A, Liu, K, Twigg, S, Blyth, K, Chesler, L

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation. od Lourenço, F, Munro, J, Brown, J, Cordero, J, Stefanatos, R, Strathdee, K, Orange, C, Feller, S, Sansom, O, Vidal, M, Murray, G, Olson, M

PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy od Dushek, O, Azad, A, Lim, S, D'Costa, Z, Jones, K, Diana, A, Sansom, O, Kruger, P, Liu, S, McKenna, W, Muschel, R, Fokas, E

Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. od Matallanas, D, Romano, D, Al-Mulla, F, O'Neill, E, Al-Ali, W, Crespo, P, Doyle, B, Nixon, C, Sansom, O, Drosten, M, Barbacid, M, Kolch, W

Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis od Kennedy, A, Morton, J, Manoharan, I, Nelson, D, Jamieson, N, Pawlikowski, J, McBryan, T, Doyle, B, McKay, C, Oien, K, Enders, G, Zhang, R, Sansom, O, Adams, P

Gemcitabine-induced TIMP1 attenuates therapy response and promotes tumor growth and liver metastasis in pancreatic cancer od D'Costa, Z, Jones, K, Azad, A, van Stiphout, R, Lim, S, Gomes, A, Kinchesh, P, Smart, S, McKenna, W, Buffa, F, Sansom, O, Muschel, R, O'Neill, E, Fokas, E

Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy. od Rajan, P, Sudbery, I, Villasevil, M, Mui, E, Fleming, J, Davis, M, Ahmad, I, Edwards, J, Sansom, O, Sims, D, Ponting, C, Heger, A, McMenemin, R, Pedley, I, Leung, H

Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy od Rajan, P, Sudbery, I, Villasevil, M, Mui, E, Fleming, J, Davis, M, Ahmad, I, Edwards, J, Sansom, O, Sims, D, Ponting, C, Heger, A, McMenemin, R, Pedley, I, Leung, H

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells od Huels, D, Bruens, L, Hodder, M, Cammareri, P, Campbell, A, Ridgway, R, Gay, D, Solar-Abboud, M, Faller, W, Nixon, C, Zeiger, L, McLaughlin, M, Morrissey, E, Winton, D, Snippert, H, van Rheenen, J, Sansom, O

A MR-based IGRT platform using the KPC transgenic mouse model of pancreatic cancer od Thompson, J, Beech, J, Allen, D, Gilchrist, S, Newman, R, Kinchesch, P, Gomes, A, D'Costa, Z, Bird, L, Vallis, K, Boghozian, R, Kavanagh, A, Sansom, O, Tullis, I, Muschel, R, Hill, M, Vojnovic, B, Smart, S, Fokas, E

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers. od Muñoz, J, Stange, D, Schepers, A, van de Wetering, M, Koo, B, Itzkovitz, S, Volckmann, R, Kung, K, Koster, J, Radulescu, S, Myant, K, Versteeg, R, Sansom, O, van Es, J, Barker, N, van Oudenaarden, A, Mohammed, S, Heck, A, Clevers, H

An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse od Kersemans, V, Beech, J, Gilchrist, S, Kinchesh, P, Allen, P, Thompson, J, Gomes, A, D'Costa, Z, Bird, L, Tullis, I, Newman, R, Corroyer-Dulmont, A, Falzone, N, Azad, A, Vallis, K, Sansom, O, Muschel, R, Vojnovic, B, Hill, M, Fokas, E, Smart, S

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. od Davis, H, Irshad, S, Bansal, M, Rafferty, H, Boitsova, T, Bardella, C, Jaeger, E, Lewis, A, Freeman-Mills, L, Giner, F, Rodenas-Cuadrado, P, Mallappa, S, Clark, S, Thomas, H, Jeffery, R, Poulsom, R, Rodriguez-Justo, M, Novelli, M, Chetty, R, Silver, A, Sansom, O, Greten, F, Wang, L, East, J, Tomlinson, I, Leedham, S

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia od Gil Vasquez, E, Nasreddin, N, Valbuena, G, Mulholland, E, Belnoue Davis, H, Eggington, H, Schenck, R, Wouters, V, Wirapati, P, Gilroy, K, Lannagan, T, Flanagan, D, Najumudeen, A, Omwenga, S, McCorrry, A, Easton, A, Koelzer, V, East, J, Morton, D, Trusolino, L, Maughan, T, Campbell, A, Loughrey, M, Dunne, P, Tsantoulis, P, Huels, D, Tejpar, S, Sansom, O, Leedham, S

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs od Drasdo, D, Fell, D, Ferrell, J, Gallahan, D, Gatenby, R, Guenther, U, Herzel, H, Junghanss, C, Kunz, M, Laplace, F, van Leeuwen, I, Lenormand, P, Levi, F, Linnebacher, M, Lowengrub, J, Maini, P, Marcus, F, Malik, A, Rateitschak, K, Sansom, O, Schafer, R, Schurrle, K, Sers, C, Schnell, S, Harms, B, Shibata, D, Tyson, J, Vera, J, White, M, Zhivotovsky, B, Jaster, R, Wolkenhauer, O, Auffray, C, Baltrusch, S, Bluthgen, N, Byrne, H, Cascante, M, Ciliberto, A, Dale, T