Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review by Marie Knufinke, Michael R. MacArthur, Collin Y. Ewald, Sarah J. Mitchell

Get full text

A naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging by Carolin Thomas, Reto Erni, Jia Yee Wu, Fabian Fischer, Greta Lamers, Giovanna Grigolon, Sarah J. Mitchell, Kim Zarse, Erick M. Carreira, Michael Ristow

Get full text

Dietary or pharmacological inhibition of insulin-like growth factor-1 protects from renal ischemia-reperfusion injury in mice by Arnaud Lyon, Thomas Agius, Michael R. Macarthur, Kevin Kiesworo, Louis Stavart, Florent Allagnat, Sarah J. Mitchell, Leonardo V. Riella, Korkut Uygun, Heidi Yeh, Sebastien Déglise, Déla Golshayan, Alban Longchamp

Get full text

Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice by Kevin Kiesworo, Thomas Agius, Michael R. Macarthur, Martine Lambelet, Arnaud Lyon, Jing Zhang, Guillermo Turiel, Zheng Fan, Sènan d’Almeida, Korkut Uygun, Heidi Yeh, Sébastien Déglise, Katrien de Bock, Sarah J. Mitchell, Alejandro Ocampo, Florent Allagnat, Alban Longchamp

Get full text

Communication of palliative care needs in discharge letters from hospice providers to primary care: a multisite sequential explanatory mixed methods study by Katharine Weetman, Jeremy Dale, Sarah J. Mitchell, Claire Ferguson, Anne M. Finucane, Peter Buckle, Elizabeth Arnold, Gemma Clarke, Despoina-Elvira Karakitsiou, Tracey McConnell, Nikhil Sanyal, Anna Schuberth, Georgia Tindle, Rachel Perry, Bhajneek Grewal, Katarzyna A. Patynowska, John I. MacArtney

Get full text

Long-term fasting: Multi-system adaptations in humans (GENESIS) study–A single-arm interventional trial by Franziska Grundler, Magalie Viallon, Magalie Viallon, Robin Mesnage, Robin Mesnage, Massimiliano Ruscica, Clemens von Schacky, Frank Madeo, Frank Madeo, Frank Madeo, Sebastian J. Hofer, Sebastian J. Hofer, Sebastian J. Hofer, Sarah J. Mitchell, Pierre Croisille, Pierre Croisille, Françoise Wilhelmi de Toledo

Get full text

Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice by Peter Kip, Thijs J. Sluiter, Michael R. MacArthur, Ming Tao, Nicky Kruit, Sarah J. Mitchell, Jonathan Jung, Sander Kooijman, Josh Gorham, Jonathan G. Seidman, Paul H. A. Quax, Julius L. Decano, Masanori Aikawa, C. Keith Ozaki, James R. Mitchell, Margreet R. de Vries

Get full text

Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21 by Thomas Agius, Raffaella Emsley, Arnaud Lyon, Michael R. MacArthur, Kevin Kiesworo, Anna Faivre, Louis Stavart, Martine Lambelet, David Legouis, Sophie de Seigneux, Déla Golshayan, Francois Lazeyras, Heidi Yeh, James F. Markmann, Korkut Uygun, Alejandro Ocampo, Sarah J. Mitchell, Florent Allagnat, Sébastien Déglise, Alban Longchamp

Get full text

HuD Regulates Coding and Noncoding RNA to Induce APP→Aβ Processing by Min-Ju Kang, Kotb Abdelmohsen, Emmette R. Hutchison, Sarah J. Mitchell, Ioannis Grammatikakis, Rong Guo, Ji Heon Noh, Jennifer L. Martindale, Xiaoling Yang, Eun Kyung Lee, Mohammad A. Faghihi, Claes Wahlestedt, Juan C. Troncoso, Olga Pletnikova, Nora Perrone-Bizzozero, Susan M. Resnick, Rafael de Cabo, Mark P. Mattson, Myriam Gorospe

Get full text

A small erythropoietin derived non-hematopoietic peptide reduces cardiac inflammation, attenuates age associated declines in heart function and prolongs healthspan by Nolan M. Winicki, Alay P. Nanavati, Christopher H. Morrell, Jack M. Moen, Jessie E. Axsom, Melissa Krawczyk, Natalia N. Petrashevskaya, Max G. Beyman, Christopher Ramirez, Irene Alfaras, Sarah J. Mitchell, Magdalena Juhaszova, Daniel R. Riordon, Mingyi Wang, Jing Zhang, Anthony Cerami, Michael Brines, Steven J. Sollott, Rafael de Cabo, Edward G. Lakatta

Get full text

Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization by Kevin Kiesworo, MS, Michael R. MacArthur, PhD, Peter Kip, MD, PhD, Thomas Agius, MS, Diane Macabrey, MS, Martine Lambelet, BS, Lauriane Hamard, PhD, C.-Keith Ozaki, MD, James R. Mitchell, PhD, Sébastien Déglise, MD, Sarah J. Mitchell, PhD, Florent Allagnat, PhD, Alban Longchamp, MD, PhD

Get full text