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Nonfucosylation of an anti-TIGIT antibody enhances FcγR engagement, driving innate immune activation and antitumor activity by Alyson J. Smith, Robert E. Thurman, Weiping Zeng, Bryan Grogan, Sasha Lucas, Guadalupe Gutierrez, Ryan A. Heiser, Serena W. Wo, Amber Blackmarr, Scott Peterson, Shyra J. Gardai
Published 2023-11-01
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854 SGN-B7H4V, a novel, investigational vedotin antibody-drug conjugate directed to the T cell checkpoint ligand B7-H4, shows promising activity in preclinical models by Elizabeth Gray, Shyra Gardai, Kelly Hensley, Sean Allred, Esther Trueblood, John Gosink, Katie Snead, Michelle Ulrich, Alyson Smith, Angela Epp, Disha Sahetya, Julie Hahn, Jane Haass, Sasha Lucas, Rogely Boyce, Piper Treuting, Chris Frantz, Jason Schrum, Natalya Nazarenko
Published 2021-11-01Article