A radioenhancing nanoparticle mediated immunoradiation improves survival and generates long-term antitumor immune memory in an anti-PD1-resistant murine lung cancer model by Yun Hu, Sébastien Paris, Hampartsoum Barsoumian, Chike O. Abana, Kewen He, Duygu Sezen, Mark Wasley, Fatemeh Masrorpour, Dawei Chen, Liangpeng Yang, Joe D. Dunn, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh

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High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC by Alexandre Reuben, Mehmet Altan, Latasha Little, Jianjun Zhang, Ajay Sheshadri, Hai T Tran, Mara B Antonoff, Stephen G Swisher, John V Heymach, Saumil Gandhi, Natalie Vokes, Ziyi Li, Ruoxing Li, Runzhe Chen, Joshua Baguley, Jefferson Sinson, Greg Lizee

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575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice by James Welsh, Sébastien Paris, Hampartsoum Barsoumian, Yun Hu, Mark Wasley, Liangpeng Yang, Quynh-Nhu Nguyen, Fatemeh Masrorpour, Saumil Gandhi, Genevieve Bertolet, Lily Schuda, Kewen He, Duygu Sezen, Joylise Mitchell, Tiffany Voss, SILVA Jordan, Claudia Kettlun Leyton, Nahum Puebla-Osorio, Angelica Cortez

Distinct patterns of auto-reactive antibodies associated with organ-specific immune-related adverse events by Mehmet Altan, Quan-Zhen Li, Qi Wang, Natalie I. Vokes, Ajay Sheshadri, Jianjun Gao, Chengsong Zhu, Hai T. Tran, Saumil Gandhi, Mara B. Antonoff, Stephen Swisher, Jing Wang, Lauren A. Byers, Noha Abdel-Wahab, Maria C. Franco-Vega, Yinghong Wang, J. Jack Lee, Jianjun Zhang, John V. Heymach

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Superior antitumor immune response achieved with proton over photon immunoradiotherapy is amplified by the nanoradioenhancer NBTXR3 by Yun Hu, Sébastien Paris, Narayan Sahoo, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Ailing Huang, Jordan Da Silva, Célia Bienassis, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Thomas Riad, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh

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Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of LAG3 and TIGIT improves the treatment efficacy in anti-PD1 resistant lung cancer by Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum B. Barsoumian, Kewen He, Duygu Sezen, Dawei Chen, Mark Wasley, Jordan DA SILVA, Joylise A. Mitchell, Tiffany A. Voss, Fatemeh Masrorpour, Claudia Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh

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Nanoparticle-enhanced proton beam immunoradiotherapy drives immune activation and durable tumor rejection by Yun Hu, Sébastien Paris, Narayan Sahoo, Genevieve Bertolet, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Jordan Da Silva, Ailing Huang, Denaha J. Doss, David P. Pollock, Ethan Hsu, Nanez Selene, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Shonik Ganjoo, Carola Leuschner, Jordan T. Pietz, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh

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Predicting benefit from immune checkpoint inhibitors in patients with non-small-cell lung cancer by CT-based ensemble deep learning: a retrospective study by Maliazurina B Saad, PhD, Lingzhi Hong, MD, Muhammad Aminu, MD, Natalie I Vokes, MD, Pingjun Chen, PhD, Morteza Salehjahromi, PhD, Kang Qin, MD, Sheeba J Sujit, PhD, Xuetao Lu, PhD, Elliana Young, MS, Qasem Al-Tashi, PhD, Rizwan Qureshi, PhD, Carol C Wu, ProfMD, Brett W Carter, ProfMD, Steven H Lin, ProfMD, Percy P Lee, ProfMD, Saumil Gandhi, MD, Joe Y Chang, ProfMD, Ruijiang Li, PhD, Michael F Gensheimer, MD, Heather A Wakelee, ProfMD, Joel W Neal, MD, Hyun-Sung Lee, MD, Chao Cheng, PhD, Vamsidhar Velcheti, ProfMD, Yanyan Lou, MD, Milena Petranovic, MD, Waree Rinsurongkawong, PhD, Xiuning Le, MD, Vadeerat Rinsurongkawong, PhD, Amy Spelman, PhD, Yasir Y Elamin, MD, Marcelo V Negrao, MD, Ferdinandos Skoulidis, MD, Carl M Gay, MD, Tina Cascone, MD, Mara B Antonoff, MD, Boris Sepesi, MD, Jeff Lewis, BS, Ignacio I Wistuba, ProfMD, John D Hazle, ProfPhD, Caroline Chung, MD, David Jaffray, ProfPhD, Don L Gibbons, ProfMD, Ara Vaporciyan, ProfMD, J Jack Lee, ProfPhD, John V Heymach, ProfMD, Jianjun Zhang, MD, Jia Wu, PhD

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