Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package by Savitsky, P

Other Authors: “…Savitsky, P…”

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package by Savitsky, P

Other Authors: “…Savitsky, P…”

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. by Newman, J, Aitkenhead, H, Savitsky, P, Gileadi, O

High-throughput production of human proteins for crystallization: the SGC experience. by Savitsky, P, Bray, J, Cooper, C, Marsden, B, Mahajan, P, Burgess-Brown, N, Gileadi, O

Expression and purification of recombinant human inward rectifier K+ (KCNJ) channels in Saccharomyces cerevisiae by D'Avanzo, N, Cheng, W, Xia, X, Dong, L, Savitsky, P, Nichols, C, Doyle, D

High-throughput production of human proteins for crystallization: the SGC experience. by Savitsky, P, Bray, J, Cooper, C, Marsden, B, Mahajan, P, Burgess-Brown, N, Gileadi, O

Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures. by Chatterjee, S, Zagelbaum, J, Savitsky, P, Sturzenegger, A, Huttner, D, Janscak, P, Hickson, I, Gileadi, O, Rothenberg, E

Large-scale structural analysis of the classical human protein tyrosine phosphatome. by Barr, A, Ugochukwu, E, Lee, W, King, O, Filippakopoulos, P, Alfano, I, Savitsky, P, Burgess-Brown, N, Müller, S, Knapp, S

Large-scale structural analysis of the classical human protein tyrosine phosphatome. by Barr, A, Ugochukwu, E, Lee, W, King, O, Filippakopoulos, P, Alfano, I, Savitsky, P, Burgess-Brown, N, Müller, S, Knapp, S

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition. by Soundararajan, M, Roos, A, Savitsky, P, Filippakopoulos, P, Kettenbach, A, Olsen, J, Gerber, SA, Eswaran, J, Knapp, S, Elkins, J

Structures of down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition by Soundararajan, M, Roos, A, Savitsky, P, Filippakopoulos, P, Eswaran, J, Knapp, S, Elkins, J, Kettenbach, A, Gerber, SA, Olsen, J

Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. by Filippakopoulos, P, Low, A, Sharpe, T, Uppenberg, J, Yao, S, Kuang, Z, Savitsky, P, Lewis, R, Nicholson, SE, Norton, R, Bullock, A

High throughput production of recombinant human proteins for crystallography. by Gileadi, O, Burgess-Brown, N, Colebrook, S, Berridge, G, Savitsky, P, Smee, C, Loppnau, P, Johansson, C, Salah, E, Pantic, N

Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes. by Newman, J, Savitsky, P, Allerston, C, Bizard, A, Özer, Ö, Sarlós, K, Liu, Y, Pardon, E, Steyaert, J, Hickson, I, Gileadi, O

Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation. by Keates, T, Cooper, C, Savitsky, P, Allerston, C, Phillips, C, Hammarström, M, Daga, N, Berridge, G, Mahajan, P, Burgess-Brown, N, Müller, S, Gräslund, S, Gileadi, O

Expressing the human proteome for affinity proteomics: Optimising expression of soluble protein domains and in vivo biotinylation by Keates, T, Cooper, C, Savitsky, P, Allerston, C, Phillips, C, Hammarström, M, Daga, N, Berridge, G, Mahajan, P, Burgess-Brown, N, Müller, S, Gräslund, S, Gileadi, O

Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations by Couñago, R, Allerston, C, Savitsky, P, Azevedo, H, Godoi, P, Wells, C, Mascarello, A, de Souza Gama, F, Massirer, K, Zuercher, W, Guimarães, C, Gileadi, O

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain by Picaud, S, Wells, C, Felletar, I, Brotherton, D, Martin, S, Savitsky, P, Philpott, M, Bountra, C, Lingard, H, Fedorov, O, Müller, S, Brennan, P, Knapp, S, Filippakopoulos, P, Diez-Dacal, B

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. by Picaud, S, Wells, C, Felletar, I, Brotherton, D, Martin, S, Savitsky, P, Diez-Dacal, B, Philpott, M, Bountra, C, Lingard, H, Fedorov, O, Müller, S, Brennan, P, Knapp, S, Filippakopoulos, P

Multivalent histone and DNA engagement by a PHD/BRD/PWWP triple reader cassette recruits ZMYND8 to K14ac-rich chromatin by Filippakopoulos, P, Savitsky, P, Krojer, T, Fujisawa, T, Lambert, J, Picaud, S, Wang, C, Shanle, E, Krajewski, K, Friedrichsen, H, Kanapin, A, Goding, C, Schapira, M, Samsonova, A, Stahl, B, Gingras, A