Chemical biology : from small molecules to systems biology and drug design (3 vols.) by 446340 Schreiber, Stuart L.

Development and validation of a T7 based linear amplification for genomic DNA by Schreiber Stuart L, Liu Chih Long, Bernstein Bradley E

Get full text

Empirical bayes analysis of quantitative proteomics experiments by Golub, Todd R., Schreiber, Stuart L., Gould, Robert J., Schenone, Monica, Ong, Shao-En, Margolin, Adam A., Carr, Steven A

Get full text
Get full text

Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles by Youngsaye, Willmen, Dockendorff, Chris, Hartland, Cathy L., Bittker, Joshua A., Dandapani, Sivaraman, Palmer, Michelle, Whitesell, Luke, Lindquist, Susan, Schreiber, Stuart L., Munoz, Benito

Get full text
Get full text

Quantitative-Proteomic Comparison of Alpha and Beta Cells to Uncover Novel Targets for Lineage Reprogramming by Choudhary, Amit, Hu He, Kaihui, Mertins, Philipp, Udeshi, Namrata D., Dancik, Vlado, Fomina-Yadlin, Dina, Kubicek, Stefan, Clemons, Paul A., Schreiber, Stuart L., Wagner, Bridget K., Carr, Steven A

Get full text
Get full text

Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor by Schreiber, Stuart L., Dockendorff, Chris, Aisiku, Omozuanvbo, VerPlank, Lynn, Dilks, James R., Smith, Daniel A., Gunnink, Susanna F., Dowal, Louisa, Negri, Joseph, Palmer, Michelle, MacPherson, Lawrence, Flaumenhaft, Robert

Get full text

STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability by Luo, Tuoping, Masson, Kristina, Jaffe, Jacob D., Silkworth, Whitney, Lee, Nathan Ross, Scherer, Christina A., Scholl, Claudia, Frohling, Stefan, Stern, Andrew M., Schreiber, Stuart L., Golub, Todd R., Carr, Steven A

Get full text
Get full text

Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation by Zhang, Zhengjian, Boskovic, Zarko, Hu, Wenxin, Inouye, Carla, Kim, Han-Je, Tjian, Robert, Hussain, Mahmud M., Abole, A. Katherine, Doud, Mary K., Lewis, Timothy A., Koehler, Angela Nicole, Schreiber, Stuart L.

Get full text

Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake by Dockendorff, Chris, Faloon, Patrick W., Pu, Jun, Johnston, Stephen, Bennion, Melissa, Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Yu, Miao, Penman, Marsha L, Nieland, Thomas J, Krieger, Monty

Get full text
Get full text
Get full text

Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates by Youngsaye, Willmen, Vincent, Benjamin, Hartland, Cathy L., Morgan, Barbara J., Buhrlage, Sara J., Johnston, Stephen, Bittker, Joshua A., MacPherson, Lawrence, Dandapani, Sivaraman, Palmer, Michelle, Whitesell, Luke, Lindquist, Susan, Schreiber, Stuart L., Munoz, Benito

Get full text
Get full text

Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake by Dockendorff, Chris, Faloon, Patrick W., Germain, Andrew, Youngsaye, Willmen, Nag, Partha P., Bennion, Melissa, Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Yu, Miao, Penman, Marsha L, Nieland, Thomas J, Krieger, Monty

Get full text
Get full text
Get full text

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics by Kuo, Szu-Yu, Castoreno, Adam B., Aldrich, Leslie N., Lassen, Kara G., Goel, Gautam, Dancik, Vlado, Kuballa, Petric, Latorre, Isabel, Conway, Kara L., Sarkar, Sovan, Maetzel, Dorothea, Jaenisch, Rudolf, Clemons, Paul A., Schreiber, Stuart L., Shamji, Alykhan F., Xavier, Ramnik J.

Get full text

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells by Kubicek, Stefan, Gilbert, Joshua C., Fomina-Yadlin, Dina, Gitlin, Alexander D., Yuan, Yuan, Wagner, Florence F., Holson, Edward B., Luo, Tuoping, Lewis, Timothy A., Taylor, Bradley, Gupta, Supriya, Shamji, Alykhan F., Wagner, Bridget K., Clemons, Paul A., Schreiber, Stuart L.

Get full text

Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity by Fass, Daniel M., Reis, Surya A., Ghosh, Balaram, Hennig, Krista M., Joseph, Nadine F., Zhao, Wen-Ning, Nieland, Thomas J.F., Guan, Ji-Song, Groves Kuhnle, Chelsea E., Tang, Weiping, Barker, Douglas D., Mazitschek, Ralph, Schreiber, Stuart L., Tsai, Li-Huei, Haggarty, Stephen J.

Get full text
Get full text

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport by Dockendorff, Chris, Faloon, Patrick W., Youngsaye, Willmen, Nag, Partha P., Lewis, Timothy A., Pu, Jun, Bennion, Melissa, Negri, Joseph, Paterson, Conor, Lam, Garrett, Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Yu, Miao, Penman, Marsha L, Nieland, Thomas J, Krieger, Monty

Get full text
Get full text
Get full text

Identifying the proteins to which small-molecule probes and drugs bind in cells by Ong, Shao-En, Schenone, Monica, Margolin, Adam A., Li, Xiaoyu, Do, Kathy, Doud, Mary Kathryn, Mani, D. R., Kuai, Letian, Wang, Xiang, Wood, John L., Tolliday, Nicola J., Koehler, Angela Nicole, Marcaurelle, Lisa A., Golub, Todd R., Gould, Robert J., Schreiber, Stuart L., Carr, Steven A.

Get full text

Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity by Sheppard, Hadley E, Dall’Agnese, Alessandra, Park, Woojun D, Shamim, M Hamza, Dubrulle, Julien, Johnson, Hannah L, Stossi, Fabio, Cogswell, Patricia, Sommer, Josh, Levy, Joan, Sharifnia, Tanaz, Wawer, Mathias J, Nabet, Behnam, Gray, Nathanael S, Clemons, Paul A, Schreiber, Stuart L, Workman, Paul, Young, Richard A, Lin, Charles Y

Get full text

Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics by de Waal, Luc, Lewis, Timothy A, Rees, Matthew G, Tsherniak, Aviad, Wu, Xiaoyun, Choi, Peter S, Gechijian, Lara, Hartigan, Christina, Faloon, Patrick W, Hickey, Mark J, Tolliday, Nicola, Carr, Steven A, Clemons, Paul A, Munoz, Benito, Wagner, Bridget K, Shamji, Alykhan F, Schenone, Monica, Burgin, Alex B, Schreiber, Stuart L, Greulich, Heidi, Meyerson, Matthew, Koehler, Angela Nicole

Get full text

DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets by Hanaford, A. R., Price, A., Kahlert, U. D., Maciaczyk, J., Nikkhah, G., Dancik, V., Seashore-Ludlow, B., Viswanathan, V., Rees, M. G., Eberhart, C. G., Raabe, E. H., Archer, Tenley, Kim, Jong Wook, Ehrenberger, Tobias, Clemons, Paul A, Stewart, Michelle L., Shamji, Alykhan, Fraenkel, Ernest, Pomeroy, Scott L., Tamayo, Pablo, Schreiber, Stuart L., Mesirov, Jill P.

Get full text
Get full text
Get full text
Get full text

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense by Lassen, Kara G., Kuballa, Petric, Conway, Kara L., Patel, Khushbu, Becker, Christine E., Peloquin, Joanna M., Villablanca, Eduardo J., Norman, Jason M., Liu, Ta-Chung, Heath, Robert J. W., Becker, Morgan L., Fagbami, Lola, Horn, Heiko, Mercer, Johnathan, Yilmaz, Omer, Jaffe, Jacob D., Shamji, Alykhan F., Bahn, Atul K., Carr, Steven A., Daly, Mark J., Virgin, Herbert W., Schreiber, Stuart L., Stappenbeck, Thaddeus S., Xavier, Ramnik J.

Get full text
Get full text