STAT1 signaling shields T cells from NK cell-mediated cytotoxicity מאת Yu Hui Kang, Amlan Biswas, Michael Field, Scott B. Snapper

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16S rRNA sequencing analysis: the devil is in the details מאת Amy M. Tsou, Scott W. Olesen, Eric J. Alm, Scott B. Snapper

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Editorial: Inborn errors of immunity and mucosal immunity מאת Elena Wen-Yuan Hsieh, Elena Wen-Yuan Hsieh, Scott B. Snapper, Edwin F. de Zoeten

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Discordance between a deep learning model and clinical-grade variant pathogenicity classification in a rare disease cohort מאת Sek Won Kong, In-Hee Lee, Lauren V. Collen, Michael Field, Arjun K. Manrai, Scott B. Snapper, Kenneth D. Mandl

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Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier מאת John J. Garber, Emily M. Mallick, Karen M. Scanlon, Jerrold R. Turner, Michael S. Donnenberg, John M. Leong, Scott B. Snapper

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Nuclear Wiskott–Aldrich syndrome protein co-regulates T cell factor 1-mediated transcription in T cells מאת Nikolai V. Kuznetsov, Bader Almuzzaini, Joanna S. Kritikou, Marisa A. P. Baptista, Mariana M. S. Oliveira, Marton Keszei, Scott B. Snapper, Piergiorgio Percipalle, Lisa S. Westerberg

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N-wasp is essential for the negative regulation of B cell receptor signaling. מאת Chaohong Liu, Xiaoming Bai, Junfeng Wu, Shruti Sharma, Arpita Upadhyaya, Carin I M Dahlberg, Lisa S Westerberg, Scott B Snapper, Xiaodong Zhao, Wenxia Song

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Cytotoxic T Lymphocyte Antigen 4 Haploinsufficiency Presenting As Refractory Celiac-Like Disease: Case Report מאת Lauren V. Collen, Carlos Andres Salgado, Bin Bao, Erin Janssen, Dascha Weir, Jeffrey Goldsmith, Alan Leichtner, Nasim Sabery Khavari, Yael Gernez, Scott B. Snapper

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Enterohemorrhagic E. coli requires N-WASP for efficient type III translocation but not for EspFU-mediated actin pedestal formation. מאת Didier Vingadassalom, Kenneth G Campellone, Michael J Brady, Brian Skehan, Scott E Battle, Douglas Robbins, Archana Kapoor, Gail Hecht, Scott B Snapper, John M Leong

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AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice מאת Jeremy A. Goettel, Roopali Gandhi, Jessica E. Kenison, Ada Yeste, Gopal Murugaiyan, Sharmila Sambanthamoorthy, Alexandra E. Griffith, Bonny Patel, Dror S. Shouval, Howard L. Weiner, Scott B. Snapper, Francisco J. Quintana

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RIPK1 mutations causing infantile-onset IBD with inflammatory and fistulizing features מאת Mutaz Sultan, Mohammad Adawi, Nitzan Kol, Nitzan Kol, Nitzan Kol, Blake McCourt, Blake McCourt, Ihda Adawi, Liran Baram, Liran Baram, Noa Tal, Noa Tal, Lael Werner, Lael Werner, Atar Lev, Atar Lev, Atar Lev, Atar Lev, Scott B. Snapper, Scott B. Snapper, Ortal Barel, Ortal Barel, Ortal Barel, Liza Konnikova, Liza Konnikova, Raz Somech, Raz Somech, Raz Somech, Raz Somech, Dror S. Shouval, Dror S. Shouval

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CCR2 promotes monocyte recruitment and intestinal inflammation in mice lacking the interleukin-10 receptor מאת Shorouk El Sayed, Izabel Patik, Naresh S. Redhu, Jonathan N. Glickman, Konstantinos Karagiannis, El Sayed Y. El Naenaeey, Gamal A. Elmowalid, Ashraf M. Abd El Wahab, Scott B. Snapper, Bruce H. Horwitz

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Alterations in T and B Cell Receptor Repertoires Patterns in Patients With IL10 Signaling Defects and History of Infantile-Onset IBD מאת Lael Werner, Lael Werner, Yu Nee Lee, Yu Nee Lee, Yu Nee Lee, Yu Nee Lee, Erez Rechavi, Erez Rechavi, Erez Rechavi, Erez Rechavi, Atar Lev, Atar Lev, Atar Lev, Atar Lev, Baruch Yerushalmi, Galina Ling, Neil Shah, Holm H. Uhlig, Holm H. Uhlig, Holm H. Uhlig, Batia Weiss, Batia Weiss, Raz Somech, Raz Somech, Raz Somech, Raz Somech, Scott B. Snapper, Scott B. Snapper, Dror S. Shouval, Dror S. Shouval

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N-wasp is required for structural integrity of the blood-testis barrier. מאת Xiang Xiao, Dolores D Mruk, Elizabeth I Tang, R'ada Massarwa, Ka Wai Mok, Nan Li, Chris K C Wong, Will M Lee, Scott B Snapper, Ben-Zion Shilo, Eyal D Schejter, C Yan Cheng

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In utero human intestine harbors unique metabolome, including bacterial metabolites מאת Yujia Li, Jessica M. Toothaker, Shira Ben-Simon, Lital Ozeri, Ron Schweitzer, Blake T. McCourt, Collin C. McCourt, Lael Werner, Scott B. Snapper, Dror S. Shouval, Soliman Khatib, Omry Koren, Sameer Agnihorti, George Tseng, Liza Konnikova

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Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis מאת Iddo Vardi, Iddo Vardi, Iddo Vardi, Iddo Vardi, Irit Chermesh, Lael Werner, Lael Werner, Ortal Barel, Ortal Barel, Ortal Barel, Tal Freund, Tal Freund, Collin McCourt, Yael Fisher, Marina Pinsker, Marina Pinsker, Elisheva Javasky, Elisheva Javasky, Elisheva Javasky, Batia Weiss, Batia Weiss, Gideon Rechavi, Gideon Rechavi, Gideon Rechavi, David Hagin, David Hagin, Scott B. Snapper, Scott B. Snapper, Raz Somech, Raz Somech, Raz Somech, Raz Somech, Liza Konnikova, Liza Konnikova, Liza Konnikova, Dror S. Shouval, Dror S. Shouval

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Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor מאת Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz

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Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes מאת Alex S. Genshaft, Carly G. K. Ziegler, Constantine N. Tzouanas, Benjamin E. Mead, Alex M. Jaeger, Andrew W. Navia, Ryan P. King, Miyeko D. Mana, Siyi Huang, Vanessa Mitsialis, Scott B. Snapper, Ömer H. Yilmaz, Tyler Jacks, Jeffrey F. Van Humbeck, Alex K. Shalek

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Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes מאת Alex S Genshaft, Carly G. K. Ziegler, Constantine N. Tzouanas, Benjamin E. Mead, Alex M. Jaeger, Andrew W. Navia, Ryan P. King, Miyeko D. Mana, Siyi Huang, Vanessa Mitsialis, Scott B. Snapper, Ömer H. Yilmaz, Tyler Jacks, Jeffrey F. Van Humbeck, Alex K. Shalek

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Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells מאת Joanna S. Kritikou, Mariana M.S. Oliveira, Julien Record, Mezida B. Saeed, Saket M. Nigam, Minghui He, Marton Keszei, Arnika K. Wagner, Hanna Brauner, Anton Sendel, Saikiran K. Sedimbi, Stamatina Rentouli, David P. Lane, Scott B. Snapper, Klas Kärre, Peter Vandenberghe, Jordan S. Orange, Lisa S. Westerberg

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