Considering the possibilities and pitfalls of Generative Pre-trained Transformer 3 (GPT-3) in healthcare delivery af Diane M. Korngiebel, Sean D. Mooney

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Ten simple rules for a community computational challenge. af Iddo Friedberg, Mark N Wass, Sean D Mooney, Predrag Radivojac

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Evaluation of the secondary use of electronic health records to detect seasonal, holiday-related, and rare events related to traumatic injury and poisoning af Timothy Bergquist, Vikas Pejaver, Noah Hammarlund, Sean D. Mooney, Stephen J. Mooney

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Data science in clinical and translational research: Improving the health of the data to knowledge pipeline af Christopher J. Lindsell, Gina-Maria Pomann, Robert A. Oster, Sean D. Mooney, Felicity T. Enders

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The Automatic Context Measurement Tool (ACMT) to Compile Participant-Specific Built and Social Environment Measures for Health Research: Development and Usability Study af Weipeng Zhou, Amy Youngbloom, Xinyang Ren, Brian E Saelens, Sean D Mooney, Stephen J Mooney

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A Multifaceted benchmarking of synthetic electronic health record generation models af Chao Yan, Yao Yan, Zhiyu Wan, Ziqi Zhang, Larsson Omberg, Justin Guinney, Sean D. Mooney, Bradley A. Malin

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New Drosophila Long-Term Memory Genes Revealed by Assessing Computational Function Prediction Methods af Balint Z. Kacsoh, Stephen Barton, Yuxiang Jiang, Naihui Zhou, Sean D. Mooney, Iddo Friedberg, Predrag Radivojac, Casey S. Greene, Giovanni Bosco

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ShareDNA: a smartphone app to facilitate family communication of genetic results af Chethan Jujjavarapu, Jeevan Anandasakaran, Laura M. Amendola, Cameron Haas, Elizabeth Zampino, Nora B. Henrikson, Gail P. Jarvik, Sean D. Mooney

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Predicting decompression surgery by applying multimodal deep learning to patients’ structured and unstructured health data af Chethan Jujjavarapu, Pradeep Suri, Vikas Pejaver, Janna Friedly, Laura S. Gold, Eric Meier, Trevor Cohen, Sean D. Mooney, Patrick J. Heagerty, Jeffrey G. Jarvik

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Pathogenicity and functional impact of non-frameshifting insertion/deletion variation in the human genome. af Kymberleigh A Pagel, Danny Antaki, AoJie Lian, Matthew Mort, David N Cooper, Jonathan Sebat, Lilia M Iakoucheva, Sean D Mooney, Predrag Radivojac

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Harnessing Innovative Technologies to Train Nurses in Suicide Safety Planning With Hospitalized Patients: Protocol for Formative and Pilot Feasibility Research af Doyanne Darnell, Patricia A Areán, Shannon Dorsey, David C Atkins, Michael J Tanana, Tad Hirsch, Sean D Mooney, Edwin D Boudreaux, Katherine Anne Comtois

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Evaluating construct validity of computable acute respiratory distress syndrome definitions in adults hospitalized with COVID-19: an electronic health records based approach af Neha A. Sathe, Su Xian, F. Linzee Mabrey, David R. Crosslin, Sean D. Mooney, Eric D. Morrell, Kevin Lybarger, Meliha Yetisgen, Gail P. Jarvik, Pavan K. Bhatraju, Mark M. Wurfel

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Inferring the molecular and phenotypic impact of amino acid variants with MutPred2 af Vikas Pejaver, Jorge Urresti, Jose Lugo-Martinez, Kymberleigh A. Pagel, Guan Ning Lin, Hyun-Jun Nam, Matthew Mort, David N. Cooper, Jonathan Sebat, Lilia M. Iakoucheva, Sean D. Mooney, Predrag Radivojac

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Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells af Karen L. Ring, Mahru C. An, Ningzhe Zhang, Robert N. O’Brien, Eliana Marisa Ramos, Fuying Gao, Robert Atwood, Barbara J. Bailus, Simon Melov, Sean D. Mooney, Giovanni Coppola, Lisa M. Ellerby

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Medium-Chain Acyl-CoA Deficiency: Outlines from Newborn Screening, In Silico Predictions, and Molecular Studies af Serena Catarzi, Anna Caciotti, Janita Thusberg, Rodolfo Tonin, Sabrina Malvagia, Giancarlo la Marca, Elisabetta Pasquini, Catia Cavicchi, Lorenzo Ferri, Maria A. Donati, Federico Baronio, Renzo Guerrini, Sean D. Mooney, Amelia Morrone

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Postnatal Conditional Deletion of <i>Bcl11b</i> in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease af Sicheng Song, Jordi Creus Muncunill, Carlos Galicia Aguirre, Kizito-Tshitoko Tshilenge, B. Wade Hamilton, Akos A. Gerencser, Houda Benlhabib, Maria-Daniela Cirnaru, Mark Leid, Sean D. Mooney, Lisa M. Ellerby, Michelle E. Ehrlich

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A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease. af John P Miller, Bridget E Yates, Ismael Al-Ramahi, Ari E Berman, Mario Sanhueza, Eugene Kim, Maria de Haro, Francesco DeGiacomo, Cameron Torcassi, Jennifer Holcomb, Juliette Gafni, Sean D Mooney, Juan Botas, Lisa M Ellerby, Robert E Hughes

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Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation af Maria-Daniela Cirnaru, Sicheng Song, Kizito-Tshitoko Tshilenge, Chuhyon Corwin, Justyna Mleczko, Carlos Galicia Aguirre, Houda Benlhabib, Jaroslav Bendl, Pasha Apontes, John Fullard, Jordi Creus-Muncunill, Azadeh Reyahi, Ali M Nik, Peter Carlsson, Panos Roussos, Sean D Mooney, Lisa M Ellerby, Michelle E Ehrlich

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SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells af Christopher D. Wiley, Su Liu, Chandani Limbad, Anna M. Zawadzka, Jennifer Beck, Marco Demaria, Robert Artwood, Fatouma Alimirah, Jose-Alberto Lopez-Dominguez, Chisaka Kuehnemann, Steven R. Danielson, Natan Basisty, Herbert G. Kasler, Tal Ronnen Oron, Pierre-Yves Desprez, Sean D. Mooney, Bradford W. Gibson, Birgit Schilling, Judith Campisi, Pankaj Kapahi

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Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework af Gustavo Glusman, Peter W. Rose, Andreas Prlić, Jennifer Dougherty, José M. Duarte, Andrew S. Hoffman, Geoffrey J. Barton, Emøke Bendixen, Timothy Bergquist, Christian Bock, Elizabeth Brunk, Marija Buljan, Stephen K. Burley, Binghuang Cai, Hannah Carter, JianJiong Gao, Adam Godzik, Michael Heuer, Michael Hicks, Thomas Hrabe, Rachel Karchin, Julia Koehler Leman, Lydie Lane, David L. Masica, Sean D. Mooney, John Moult, Gilbert S. Omenn, Frances Pearl, Vikas Pejaver, Sheila M. Reynolds, Ariel Rokem, Torsten Schwede, Sicheng Song, Hagen Tilgner, Yana Valasatava, Yang Zhang, Eric W. Deutsch

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