The 4th NextGen therapies for SJIA and MAS: part 2 phenotypes of refractory SJIA and the landscape for clinical trials in refractory SJIA by Grant Schulert, Sebastiaan J. Vastert, Alexei A. Grom

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Contradictory and weak evidence on the effectiveness of anti-emetics for MTX-intolerance in JIA-patients by Casper G. Schoemaker, E. H. Pieter van Dijkhuizen, Sebastiaan J. Vastert

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Restoring T Cell Tolerance, Exploring the Potential of Histone Deacetylase Inhibitors for the Treatment of Juvenile Idiopathic Arthritis by Lotte Nijhuis, Janneke G. C. Peeters, Sebastiaan J. Vastert, Jorg van Loosdregt

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The 4th NextGen Therapies for SJIA and MAS: part 1 the elephant in the room: diagnostic/classification criteria for systemic juvenile idiopathic arthritis and adult-onset still’s d... by Peter A. Nigrovic, Fabrizio de Benedetti, Yukiko Kimura, Daniel J. Lovell, Sebastiaan J. Vastert

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Tissue–Resident Memory T Cells in Chronic Inflammation—Local Cells with Systemic Effects? by Anoushka Ashok Kumar Samat, Jolijn van der Geest, Sebastiaan J. Vastert, Jorg van Loosdregt, Femke van Wijk

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Conventional dendritic cells type 1 are strongly enriched, quiescent and relatively tolerogenic in local inflammatory arthritis by Arjan Boltjes, Anoushka Ashok Kumar Samat, Maud Plantinga, Michal Mokry, Bas Castelijns, Joost F. Swart, Sebastiaan J. Vastert, Sebastiaan J. Vastert, Menno Creyghton, Menno Creyghton, Stefan Nierkens, Stefan Nierkens, Jorg van Loosdregt, Jorg van Loosdregt, Femke van Wijk, Femke van Wijk

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Serum biomarkers confirming stable remission in inflammatory bowel disease by Christoph Kessel, Miha Lavric, Toni Weinhage, Markus Brueckner, Sytze de Roock, Jan Däbritz, Jakob Weber, Sebastiaan J. Vastert, Dirk Foell

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Juvenile Arthritis Patients Suffering from Chronic Inflammation Have Increased Activity of Both IDO and GTP-CH1 Pathways But Decreased BH4 Efficacy: Implications for Well-Being, In... by Gerdien A. H. Korte-Bouws, Eline Albers, Marije Voskamp, Hendrikus Hendriksen, Lidewij R. de Leeuw, Onur Güntürkün, Sytze de Roock, Sebastiaan J. Vastert, S. Mechiel Korte

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CBP/P300 Inhibition Impairs CD4+ T Cell Activation: Implications for Autoimmune Disorders by Lucas Wilhelmus Picavet, Anoushka A. K. Samat, Jorg Calis, Lotte Nijhuis, Rianne Scholman, Michal Mokry, David F. Tough, Rabinder K. Prinjha, Sebastiaan J. Vastert, Jorg van Loosdregt

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Autoimmune disease-associated gene expression is reduced by BET-inhibition by Janneke G.C. Peeters, Stephin J. Vervoort, Gerdien Mijnheer, Sytze de Roock, Sebastiaan J. Vastert, Edward E.S. Nieuwenhuis, Femke van Wijk, Berent J. Prakken, Michal Mokry, Jorg van Loosdregt

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The safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade: an international survey by Jerold Jeyaratnam, Nienke M. ter Haar, Helen J. Lachmann, Ozgur Kasapcopur, Amanda K. Ombrello, Donato Rigante, Fatma Dedeoglu, Ezgi H. Baris, Sebastiaan J. Vastert, Nico M. Wulffraat, Joost Frenkel

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Patient’s experiences with the care for juvenile idiopathic arthritis across Europe by E. H. Pieter. van Dijkhuizen, Tsipi Egert, Yona Egert, Wendy Costello, Casper Schoemaker, Marlous Fernhout, Mirjam Kepic, Alberto Martini, Silvia Scala, Ingrid Rotstein-Grein, Sebastiaan J. Vastert, Nico M. Wulffraat

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Real-world data reveals the complexity of disease modifying anti-rheumatic drug treatment patterns in juvenile idiopathic arthritis: an observational study by Luiza R. Grazziotin, Gillian Currie, Marinka Twilt, Maarten J. Ijzerman, Michelle M. A. Kip, Hendrik Koffijberg, Susanne M. Benseler, Joost F. Swart, Sebastiaan J. Vastert, Nico M. Wulffraat, Rae S. M. Yeung, Deborah A. Marshall

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N⁶-Methyladenosine Directly Regulates CD40L Expression in CD4⁺ T Lymphocytes by Ellen C. N. van Vroonhoven, Lucas W. Picavet, Rianne C. Scholman, Noortje A. M. van den Dungen, Michal Mokry, Anouk Evers, Robert J. Lebbink, Jorg J. A. Calis, Sebastiaan J. Vastert, Jorg van Loosdregt

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Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression by Janneke G.C. Peeters, Stephin J. Vervoort, Sander C. Tan, Gerdien Mijnheer, Sytze de Roock, Sebastiaan J. Vastert, Edward E.S. Nieuwenhuis, Femke van Wijk, Berent J. Prakken, Menno P. Creyghton, Paul J. Coffer, Michal Mokry, Jorg van Loosdregt

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Seeking the state of the art in standardized measurement of health care resource use and costs in juvenile idiopathic arthritis: a scoping review by Michelle M. A. Kip, Gillian Currie, Deborah A. Marshall, Luiza Grazziotin Lago, Marinka Twilt, Sebastiaan J. Vastert, Joost F. Swart, Nico Wulffraat, Rae S. M. Yeung, Susanne M. Benseler, Maarten J. IJzerman, on behalf of the UCAN CAN-DU Health Economics Working Group

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m⁶A Reader YTHDC1 Impairs Respiratory Syncytial Virus Infection by Downregulating Membrane CX3CR1 Expression by Lucas W. Picavet, Ellen C. N. van Vroonhoven, Rianne C. Scholman, Yesper T. H. Smits, Rupa Banerjee, Sjanna B. Besteman, Mattheus C. Viveen, Michiel M. van der Vlist, Marvin E. Tanenbaum, Robert J. Lebbink, Sebastiaan J. Vastert, Jorg van Loosdregt

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Factors associated with care- and health-related quality of life of caregivers of children with juvenile idiopathic arthritis by Luiza R. Grazziotin, Gillian Currie, Marinka Twilt, Maarten J. IJzerman, Michelle M. A. Kip, Hendrik Koffijberg, Gouke Bonsel, Susanne M. Benseler, Joost F. Swart, Sebastiaan J. Vastert, Nico M. Wulffraat, Rae S. M. Yeung, Wineke Armbrust, J. Merlijn van den Berg, Deborah A. Marshall

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Withdrawing biologics in non-systemic JIA: what matters to pediatric rheumatologists? by Janine A. van Til, Michelle M. A. Kip, Ellen J. H. Schatorjé, Gillian Currie, Marinka Twilt, Susanne M. Benseler, Joost F. Swart, Sebastiaan J. Vastert, Nico Wulffraat, Rae S. M. Yeung, C. G. M. (Karin) Groothuis-Oudshoorn, Sanne Warta, Deborah A. Marshall, Maarten J. IJzerman, on behalf of the UCAN CAN-DU, UCAN CURE consortia

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Dutch juvenile idiopathic arthritis patients, carers and clinicians create a research agenda together following the James Lind Alliance method: a study protocol by Casper G. Schoemaker, Wineke Armbrust, Joost F. Swart, Sebastiaan J. Vastert, Jorg van Loosdregt, Anouk Verwoerd, Caroline Whiting, Katherine Cowan, Wendy Olsder, Els Versluis, Rens van Vliet, Marlous J. Fernhout, Sanne L. Bookelman, Jeannette Cappon, J. Merlijn van den Berg, Ellen Schatorjé, Petra C. E. Hissink Muller, Sylvia Kamphuis, Joke de Boer, Otto T. H. M. Lelieveld, Janjaap van der Net, Karin R. Jongsma, Annemiek van Rensen, Christine Dedding, Nico M. Wulffraat

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