BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response by Janakiram R. Vangala, Ajay Potluri, Senthil K. Radhakrishnan

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p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition by Senthil K Radhakrishnan, Willem den Besten, Raymond J Deshaies

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QPI Allows in vitro Drug Screening of Triple Negative Breast Cancer PDX Tumors and Fine Needle Biopsies by Graeme F. Murray, Tia H. Turner, Tia H. Turner, Daniel Guest, Kevin A. Leslie, Mohammad A. Alzubi, Senthil K. Radhakrishnan, Senthil K. Radhakrishnan, J. Chuck Harrell, J. Chuck Harrell, Jason Reed, Jason Reed

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Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer by Holly A. Byers, Amy N. Brooks, Janakiram R. Vangala, Jacqueline M. Grible, Alex Feygin, Charles V. Clevenger, J. Chuck Harrell, Senthil K. Radhakrishnan

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Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity by Frederick M. Tomlin, Ulla I. M. Gerling-Driessen, Yi-Chang Liu, Ryan A. Flynn, Janakiram R. Vangala, Christian S. Lentz, Sandra Clauder-Muenster, Petra Jakob, William F. Mueller, Diana Ordoñez-Rueda, Malte Paulsen, Naoko Matsui, Deirdre Foley, Agnes Rafalko, Tadashi Suzuki, Matthew Bogyo, Lars M. Steinmetz, Senthil K. Radhakrishnan, Carolyn R. Bertozzi

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