Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO Autor James Chen, Alex J. Noble, Jin Young Kang, Seth A. Darst

Získat plný text

Structure of a bacterial RNA polymerase holoenzyme open promoter complex Autor Brian Bae, Andrey Feklistov, Agnieszka Lass-Napiorkowska, Robert Landick, Seth A Darst

Získat plný text

CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex Autor Brian Bae, James Chen, Elizabeth Davis, Katherine Leon, Seth A Darst, Elizabeth A Campbell

Získat plný text

Complete structural model of Escherichia coli RNA polymerase from a hybrid approach. Autor Natacha Opalka, Jesse Brown, William J Lane, Kelly-Anne F Twist, Robert Landick, Francisco J Asturias, Seth A Darst

Získat plný text

Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts Autor Hande Boyaci, James Chen, Mirjana Lilic, Margaret Palka, Rachel Anne Mooney, Robert Landick, Seth A Darst, Elizabeth A Campbell

Získat plný text

E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation Autor James Chen, Saumya Gopalkrishnan, Courtney Chiu, Albert Y Chen, Elizabeth A Campbell, Richard L Gourse, Wilma Ross, Seth A Darst

Získat plný text

Structural basis for transcription complex disruption by the Mfd translocase Autor Jin Young Kang, Eliza Llewellyn, James Chen, Paul Dominic B Olinares, Joshua Brewer, Brian T Chait, Elizabeth A Campbell, Seth A Darst

Získat plný text

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA Autor Elizabeth A Hubin, Allison Fay, Catherine Xu, James M Bean, Ruth M Saecker, Michael S Glickman, Seth A Darst, Elizabeth A Campbell

Získat plný text

Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex Autor Jin Young Kang, Paul Dominic B Olinares, James Chen, Elizabeth A Campbell, Arkady Mustaev, Brian T Chait, Max E Gottesman, Seth A Darst

Získat plný text

A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance Autor Samantha L. Grimes, Young J. Choi, Anoosha Banerjee, Gabriel Small, Jordan Anderson-Daniels, Jennifer Gribble, Andrea J. Pruijssers, Maria L. Agostini, Alexandra Abu-Shmais, Xiaotao Lu, Seth A. Darst, Elizabeth Campbell, Mark R. Denison

Získat plný text