Authors’ response to “Comment on: ‘Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia’” by Boris E. Shmukler, Nathan D. Lawson, Barry H. Paw, Seth L. Alper

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Hereditary anemia caused by multilocus inheritance of <i>PIEZO1</i>, <i>SLC4A1</i> and <i>ABCB6</i> mutations: a diagnostic and therapeutic challenge by Barbara Eleni Rosato, Seth L. Alper, Giovanna Tomaiuolo, Roberta Russo, Achille Iolascon, Immacolata Andolfo

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Challenges to dialysis treatment during the COVID-19 pandemic: a qualitative study of patients’ and experts’ perspectives by Krystell Oviedo Flores, Krystell Oviedo Flores, Tanja Stamm, Tanja Stamm, Seth L. Alper, Valentin Ritschl, Valentin Ritschl, Andreas Vychytil

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Activation of 2‐oxoglutarate receptor 1 (OXGR1) by α‐ketoglutarate (αKG) does not detectably stimulate Pendrin‐mediated anion exchange in Xenopus oocytes by John F. Heneghan, Amar J. Majmundar, Alicia Rivera, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder, Friedhelm Hildebrandt, Seth L. Alper

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K-CL co-transport plays an important role in normal and β thalassemic erythropoiesis by Lucia De Franceschi, Luisa Ronzoni, Maria Domenica Cappellini, Flora Cimmino, Angela Siciliano, Seth L. Alper, Veronica Servedio, Christian Pozzobon, Achille Iolascon

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Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia by Boris E. Shmukler, Nicholas C. Huston, Jonathan N. Thon, Chih-Wen Ni, George Kourkoulis, Nathan D. Lawson, Barry H. Paw, Seth L. Alper

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Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone. by Dale W Hailey, Brock Roberts, Kelly N Owens, Andrew K Stewart, Tor Linbo, Remy Pujol, Seth L Alper, Edwin W Rubel, David W Raible

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Effect of Nitric Oxide Pathway Inhibition on the Evolution of Anaphylactic Shock in Animal Models: A Systematic Review by Maryam Alfalasi, Sarah Alzaabi, Linda Östlundh, Rami H. Al-Rifai, Suhail Al-Salam, Paul Michel Mertes, Seth L. Alper, Elhadi H. Aburawi, Abdelouahab Bellou

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Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis by Enrica Federti, Alessandro Matte, Veronica Riccardi, Kevin Peikert, Seth L. Alper, Adrian Danek, Ruth H. Walker, Angela Siciliano, Iana Iatcenko, Andreas Hermann, Lucia De Franceschi

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Increased Red Cell KCNN4 Activity in Sporadic Hereditary Xerocytosis Associated With Enhanced Single Channel Pressure Sensitivity of PIEZO1 Mutant V598M by Radhakrishnan Gnanasambandam, Alicia Rivera, David H. Vandorpe, Boris E. Shmukler, Carlo Brugnara, L. Michael Snyder, Immacolata Andolfo, Achille Iolascon, Paulo A. Silveira, Nelson Hamerschlak, Philip Gottlieb, Seth L. Alper

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Activation of PIEZO1 Attenuates Kidney Cystogenesis In Vitro and Ex Vivo by Qingfeng Fan, Mohamad Hadla, Zack Peterson, Grace Nelson, Hong Ye, Xiaofang Wang, Jean Marc Mardirossian, Peter C. Harris, Seth L. Alper, Y.S. Prakash, Arthur Beyder, Vicente E. Torres, Fouad T. Chebib

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Peritoneal Dialysis Fluid Supplementation with Alanyl-Glutamine Attenuates Conventional Dialysis Fluid-Mediated Endothelial Cell Injury by Restoring Perturbed Cytoprotective Respon... by Rebecca Herzog, Maria Bartosova, Silvia Tarantino, Anja Wagner, Markus Unterwurzacher, Juan Manuel Sacnun, Anton M. Lichtenauer, Lilian Kuster, Betti Schaefer, Seth L. Alper, Christoph Aufricht, Claus Peter Schmitt, Klaus Kratochwill

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Functional characterization of novel ABCB6 mutations and their clinical implications in familial pseudohyperkalemia by Immacolata Andolfo, Roberta Russo, Francesco Manna, Gianluca De Rosa, Antonella Gambale, Soha Zouwail, Nicola Detta, Catia Lo Pardo, Seth L. Alper, Carlo Brugnara, Alok K. Sharma, Lucia De Franceschi, Achille Iolascon

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A <i>Grammastola spatulata</i> mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic etiolog... by David H. Vandorpe, Boris E. Shmukler, Yann Ilboudo, Swati Bhasin, Beena Thomas, Alicia Rivera, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder, Colin Sieff, Manoj Bhasin, Guillaume Lettre, Carlo Brugnara, Seth L. Alper

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Combined Treatment with KV Channel Inhibitor 4-Aminopyridine and either γ-Cystathionine Lyase Inhibitor β-Cyanoalanine or Epinephrine Restores Blood Pressure, and Improves Survival... by Abdelouahab Bellou, Nacira Sennoun, Elhadi H. Aburawi, Richard L. Jayaraj, Seth L. Alper, Ibrahim Abdallah Alfaki, Javed Yasin, Subramanian Sekar, Mohamed Shafiuallah, Suhail Al-Salam, Abderrahim Nemmar, Elsadig Kazzam, Paul Michel Mertes, Suleiman Al-Hammadi

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Countermeasures against COVID-19: how to navigate medical practice through a nascent, evolving evidence base — a European multicentre mixed methods study by Constantinos J Stefanidis, Valentin Ritschl, Rukshana Shroff, Fabian Eibensteiner, Tanja Stamm, Asil Cetin, Claus Peter Schmitt, Gema Ariceta, Sevcan Bakkaloglu, Augustina Jankauskiene, Günter Klaus, Fabio Paglialonga, Alberto Edefonti, Bruno Ranchin, Johan Vandewalle, Enrico Verrina, Karel Vondrak, Aleksandra Zurowska, Seth L Alper, Christoph Aufricht

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Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations by Shujuan Zhao, Kedous Y. Mekbib, Martijn A. van der Ent, Garrett Allington, Andrew Prendergast, Jocelyn E. Chau, Hannah Smith, John Shohfi, Jack Ocken, Daniel Duran, Charuta G. Furey, Le Thi Hao, Phan Q. Duy, Benjamin C. Reeves, Junhui Zhang, Carol Nelson-Williams, Di Chen, Boyang Li, Timothy Nottoli, Suxia Bai, Myron Rolle, Xue Zeng, Weilai Dong, Po-Ying Fu, Yung-Chun Wang, Shrikant Mane, Paulina Piwowarczyk, Katie Pricola Fehnel, Alfred Pokmeng See, Bermans J. Iskandar, Beverly Aagaard-Kienitz, Quentin J. Moyer, Evan Dennis, Emre Kiziltug, Adam J. Kundishora, Tyrone DeSpenza, Ana B. W. Greenberg, Seblewengel M. Kidanemariam, Andrew T. Hale, James M. Johnston, Eric M. Jackson, Phillip B. Storm, Shih-Shan Lang, William E. Butler, Bob S. Carter, Paul Chapman, Christopher J. Stapleton, Aman B. Patel, Georges Rodesch, Stanislas Smajda, Alejandro Berenstein, Tanyeri Barak, E. Zeynep Erson-Omay, Hongyu Zhao, Andres Moreno-De-Luca, Mark R. Proctor, Edward R. Smith, Darren B. Orbach, Seth L. Alper, Stefania Nicoli, Titus J. Boggon, Richard P. Lifton, Murat Gunel, Philip D. King, Sheng Chih Jin, Kristopher T. Kahle

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