1374 Virus-like DNA, a single-agent poly-functional therapeutic platform that potently activates anti-cancer protective immunity by Shahrooz Rabizadeh, Kayvan R Niazi, Peter A Sieling, Steve Benz, Justin Golovato

1373 SynBAd, a clinical cancer vaccine candidate, induces antigen-specific T cells and extends life in a therapeutic liver cancer model by Shahrooz Rabizadeh, Kayvan R Niazi, Peter A Sieling, Steve Benz, Justin Golovato, Aleece Nolasco

Deep Learning Implicitly Handles Tissue Specific Phenomena to Predict Tumor DNA Accessibility and Immune Activity by Kamil Wnuk, Jeremi Sudol, Kevin B. Givechian, Patrick Soon-Shiong, Shahrooz Rabizadeh, Christopher Szeto, Charles Vaske

Get full text

Single-cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis by Darrell L. Ellsworth, Heather L. Blackburn, Craig D. Shriver, Shahrooz Rabizadeh, Patrick Soon-Shiong, Rachel E. Ellsworth

Get full text

A deep learning image-based intrinsic molecular subtype classifier of breast tumors reveals tumor heterogeneity that may affect survival by Mustafa I. Jaber, Bing Song, Clive Taylor, Charles J. Vaske, Stephen C. Benz, Shahrooz Rabizadeh, Patrick Soon-Shiong, Christopher W. Szeto

Get full text

Correction to: Immunotherapy Utilizing the Combination of Natural Killer– and Antibody Dependent Cellular Cytotoxicity (ADCC)–Mediating Agents with Poly (ADP-ribose) polymerase (PA... by Kathleen E. Fenerty, Michelle Padget, Benjamin Wolfson, Sofia R. Gameiro, Zhen Su, John H. Lee, Shahrooz Rabizadeh, Patrick Soon-Shiong, James W. Hodge

Get full text

Immunotherapy utilizing the combination of natural killer– and antibody dependent cellular cytotoxicity (ADCC)–mediating agents with poly (ADP-ribose) polymerase (PARP) inhibition... by Kathleen E. Fenerty, Michelle Padget, Benjamin Wolfson, Sofia R. Gameiro, Zhen Su, John H. Lee, Shahrooz Rabizadeh, Patrick Soon-Shiong, James W. Hodge

Get full text

Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice. by Upendra K Kar, Janina Jiang, Cheryl I Champion, Sahar Salehi, Minu Srivastava, Sherven Sharma, Shahrooz Rabizadeh, Kayvan Niazi, Valerie Kickhoefer, Leonard H Rome, Kathleen A Kelly

Get full text

Overcoming hypoxia-induced functional suppression of NK cells by Jeffrey Schlom, James W Hodge, Shahrooz Rabizadeh, Patrick Soon-Shiong, Fabiola Cecchi, Todd Hembrough, Benjamin Wolfson, Kristen Solocinski, Michelle R Padget, Kellsye P Fabian, Stephen C Benz

Get full text

PD-L1 targeting high-affinity NK (t-haNK) cells induce direct antitumor effects and target suppressive MDSC populations by Jeffrey Schlom, James W Hodge, Clint T. Allen, Shahrooz Rabizadeh, Patrick Soon-Shiong, John H. Lee, Renee N. Donahue, Kristen Solocinski, Michelle R Padget, Kellsye P Fabian, Yvette Robbins

Get full text

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery by Alexander J Sercel, Alexander N Patananan, Tianxing Man, Ting-Hsiang Wu, Amy K Yu, Garret W Guyot, Shahrooz Rabizadeh, Kayvan R Niazi, Pei-Yu Chiou, Michael A Teitell

Get full text

An ACE2 Triple Decoy that neutralizes SARS-CoV-2 shows enhanced affinity for virus variants by Shiho Tanaka, Gard Nelson, C. Anders Olson, Oleksandr Buzko, Wendy Higashide, Annie Shin, Marcos Gonzalez, Justin Taft, Roosheel Patel, Sofija Buta, Ashley Richardson, Dusan Bogunovic, Patricia Spilman, Kayvan Niazi, Shahrooz Rabizadeh, Patrick Soon-Shiong

Get full text

The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex by Caroline Jochems, Sarah R. Tritsch, Karin M. Knudson, Sofia R. Gameiro, Claire Smalley Rumfield, Samuel T. Pellom, Y. Maurice Morillon, Robby Newman, Warren Marcus, Christopher Szeto, Shahrooz Rabizadeh, Hing C. Wong, Patrick Soon-Shiong, Jeffrey Schlom

Get full text

Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display by Shiho Tanaka, C. Anders Olson, Christopher O. Barnes, Wendy Higashide, Marcos Gonzalez, Justin Taft, Ashley Richardson, Marta Martin-Fernandez, Dusan Bogunovic, Priyanthi N.P. Gnanapragasam, Pamela J. Bjorkman, Patricia Spilman, Kayvan Niazi, Shahrooz Rabizadeh, Patrick Soon-Shiong

Get full text

Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice by Adrian Rice, Mohit Verma, Annie Shin, Lise Zakin, Peter Sieling, Shiho Tanaka, Joseph Balint, Kyle Dinkins, Helty Adisetiyo, Brett Morimoto, Wendy Higashide, C. Anders Olson, Shivani Mody, Patricia Spilman, Elizabeth Gabitzsch, Jeffrey T. Safrit, Shahrooz Rabizadeh, Kayvan Niazi, Patrick Soon-Shiong

Get full text

Phase I study of a multitargeted recombinant Ad5 PSA/MUC-1/brachyury-based immunotherapy vaccine in patients with metastatic castration-resistant prostate cancer (mCRPC) by Renee N Donahue, Jeffrey Schlom, James L Gulley, Ravi A Madan, Claudia Palena, Caroline Jochems, Shahrooz Rabizadeh, Patrick Soon-Shiong, Sheri McMahon, Julius Strauss, Marijo Bilusic, Fatima Karzai, Houssein Abdul Sater, Jennifer L Marté, Yo-Ting Tsai, Jason Redman, Charalampos Floudas

Get full text

Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge by Elizabeth Gabitzsch, Jeffrey T. Safrit, Mohit Verma, Adrian Rice, Peter Sieling, Lise Zakin, Annie Shin, Brett Morimoto, Helty Adisetiyo, Raymond Wong, Ashish Bezawada, Kyle Dinkins, Joseph Balint, Victor Peykov, Hermes Garban, Philip Liu, Andrew Bacon, Pete Bone, Jeff Drew, Daniel C. Sanford, Patricia Spilman, Lennie Sender, Shahrooz Rabizadeh, Kayvan Niazi, Patrick Soon-Shiong

Get full text

Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy by Jeffrey Schlom, James L Gulley, Andrew Nguyen, Shahrooz Rabizadeh, Kayvan Niazi, Patrick Soon-Shiong, Duane H Hamilton, Marieke Griffioen, Andreas Mackensen, Stephen C Benz, Patricia Spilman, Peter A Fasching, Matthias W Beckmann, Alexander Hein, Matthias Ruebner, Hannah Reimann, J Zachary Sanborn, Charles J Vaske, Edith D van der Meijden, Judith Bausenwein, Sascha Kretschmann, Karin L Lee, Anita N. Kremer

Get full text