Monitoring in practice – How are UK academic clinical trials monitored? A survey by Sharon B. Love, Victoria Yorke-Edwards, Sarah Lensen, Matthew R. Sydes

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A new trial monitoring plan (TMP) template for clinical trials: output from a Delphi process by Shiva Taheri, Victoria Yorke-Edwards, Matthew R. Sydes, Talia Isaacs, Sharon B. Love

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Uptake of the multi-arm multi-stage (MAMS) adaptive platform approach: a trial-registry review of late-phase randomised clinical trials by Nurulamin M Noor, Matthew R Sydes, Richard Kaplan, Sharon B Love, Talia Isaacs, Mahesh K B Parmar

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Use of routinely collected health data in randomised clinical trials: comparison of trial-specific death data in the BOSS trial with NHS Digital data by Sharon B. Love, Anna Kilanowski, Victoria Yorke-Edwards, Oliver Old, Hugh Barr, Clive Stokes, Catherine Kendall, Matthew R. Sydes

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Practicalities in running early-phase trials using the time-to-event continual reassessment method (TiTE-CRM) for interventions with long toxicity periods using two radiotherapy on... by Erik van Werkhoven, Samantha Hinsley, Eleni Frangou, Jane Holmes, Rosemarie de Haan, Maria Hawkins, Sarah Brown, Sharon B Love

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Monitoring advances including consent: learning from COVID-19 trials and other trials running in UKCRC registered clinical trials units during the pandemic by Sharon B. Love, Emma Armstrong, Carrie Bayliss, Melanie Boulter, Lisa Fox, Joanne Grumett, Patricia Rafferty, Barbara Temesi, Krista Wills, Andrea Corkhill

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What is the purpose of clinical trial monitoring? by Sharon B. Love, Victoria Yorke-Edwards, Elizabeth Ward, Rebecca Haydock, Katie Keen, Katie Biggs, Gosala Gopalakrishnan, Lucy Marsh, Lydia O’Sullivan, Lisa Fox, Estelle Payerne, Kerenza Hood, Garry Meakin

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Access to routinely collected health data for clinical trials – review of successful data requests to UK registries by Sarah Lensen, Archie Macnair, Sharon B. Love, Victoria Yorke-Edwards, Nurulamin M. Noor, Meredith Martyn, Alexandra Blenkinsop, Carlos Diaz-Montana, Graham Powell, Elizabeth Williamson, James Carpenter, Matthew R. Sydes

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How to design a dose-finding study using the continual reassessment method by Graham M. Wheeler, Adrian P. Mander, Alun Bedding, Kristian Brock, Victoria Cornelius, Andrew P. Grieve, Thomas Jaki, Sharon B. Love, Lang’o Odondi, Christopher J. Weir, Christina Yap, Simon J. Bond

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Outcome of central nervous system relapses in childhood acute lymphoblastic leukaemia--prospective open cohort analyses of the ALLR3 trial. by Ashish Narayan Masurekar, Catriona A Parker, Milensu Shanyinde, Anthony V Moorman, Jeremy P Hancock, Rosemary Sutton, Philip J Ancliff, Mary Morgan, Nicholas J Goulden, Chris Fraser, Peter M Hoogerbrugge, Tamas Revesz, Philip J Darbyshire, Shekhar Krishnan, Sharon B Love, Vaskar Saha

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Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer’s disease: study protocol for a randomised controlled trial (ELAD study) by Grazia Daniela Femminella, Eleni Frangou, Sharon B. Love, Gail Busza, Clive Holmes, Craig Ritchie, Robert Lawrence, Brady McFarlane, George Tadros, Basil H. Ridha, Carol Bannister, Zuzana Walker, Hilary Archer, Elizabeth Coulthard, Ben R. Underwood, Aparna Prasanna, Paul Koranteng, Salman Karim, Kehinde Junaid, Bernadette McGuinness, Ramin Nilforooshan, Ajay Macharouthu, Andrew Donaldson, Simon Thacker, Gregor Russell, Naghma Malik, Vandana Mate, Lucy Knight, Sajeev Kshemendran, John Harrison, David J. Brooks, Anthony Peter Passmore, Clive Ballard, Paul Edison

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Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units by Sharon B. Love, Fay Cafferty, Claire Snowdon, Karen Carty, Joshua Savage, Philip Pallmann, Lucy McParland, Louise Brown, Lindsey Masters, Francesca Schiavone, Dominic Hague, Stephen Townsend, Claire Amos, Annabelle South, Kate Sturgeon, Ruth Langley, Timothy Maughan, Nicholas James, Emma Hall, Sarah Kernaghan, Judith Bliss, Nick Turner, Andrew Tutt, Christina Yap, Charlotte Firth, Anthony Kong, Hisham Mehanna, Colin Watts, Robert Hills, Ian Thomas, Mhairi Copland, Sue Bell, David Sebag-Montefiore, Robert Jones, Mahesh K. B. Parmar, Matthew R. Sydes

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Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage by Alice-Maria Toader, Marion K. Campbell, Jennifer K. Quint, Michael Robling, Matthew R Sydes, Joanna Thorn, Alexandra Wright-Hughes, Ly-Mee Yu, Tom. E. F. Abbott, Simon Bond, Fergus J. Caskey, Madeleine Clout, Michelle Collinson, Bethan Copsey, Gwyneth Davies, Timothy Driscoll, Carrol Gamble, Xavier L. Griffin, Thomas Hamborg, Jessica Harris, David A. Harrison, Deena Harji, Emily J. Henderson, Pip Logan, Sharon B. Love, Laura A. Magee, Alastair O’Brien, Maria Pufulete, Padmanabhan Ramnarayan, Athanasios Saratzis, Jo Smith, Ivonne Solis-Trapala, Clive Stubbs, Amanda Farrin, Paula Williamson

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