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Targeting SARS-CoV-2 Proteases for COVID-19 Antiviral Development by Zongyang Lv, Kristin E. Cano, Lijia Jia, Marcin Drag, Tony T. Huang, Shaun K. Olsen
Published 2022-02-01
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Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL by Digant Nayak, Dongwen Lv, Yaxia Yuan, Peiyi Zhang, Wanyi Hu, Anindita Nayak, Eliza A. Ruben, Zongyang Lv, Patrick Sung, Robert Hromas, Guangrong Zheng, Daohong Zhou, Shaun K. Olsen
Published 2024-03-01
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Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts by Daniel Jan Strub, Michał Talma, Maria Strub, Wioletta Rut, Mikolaj Zmudzinski, Władysław Brud, Johan Neyts, Laura Vangeel, Linlin Zhang, Xinyuanyuan Sun, Zongyang Lv, Digant Nayak, Shaun K. Olsen, Rolf Hilgenfeld, Dirk Jochmans, Marcin Drąg
Published 2022-08-01
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Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer by Mohammad Afsar, GuanQun Liu, Lijia Jia, Eliza A. Ruben, Digant Nayak, Zuberwasim Sayyad, Priscila dos Santos Bury, Kristin E. Cano, Anindita Nayak, Xiang Ru Zhao, Ankita Shukla, Patrick Sung, Elizabeth V. Wasmuth, Michaela U. Gack, Shaun K. Olsen
Published 2023-08-01
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Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase by Mikolaj Zmudzinski, Wioletta Rut, Kamila Olech, Jarosław Granda, Mirosław Giurg, Małgorzata Burda-Grabowska, Rafał Kaleta, Michala Zgarbova, Renata Kasprzyk, Linlin Zhang, Xinyuanyuan Sun, Zongyang Lv, Digant Nayak, Malgorzata Kesik-Brodacka, Shaun K. Olsen, Jan Weber, Rolf Hilgenfeld, Jacek Jemielity, Marcin Drag
Published 2023-06-01
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Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6 by Lingmin Yuan, Fei Gao, Zongyang Lv, Digant Nayak, Anindita Nayak, Priscila dos Santos Bury, Kristin E. Cano, Lijia Jia, Natalia Oleinik, Firdevs Cansu Atilgan, Besim Ogretmen, Katelyn M. Williams, Christopher Davies, Farid El Oualid, Elizabeth V. Wasmuth, Shaun K. Olsen
Published 2022-08-01
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