P460: Gene- and variant-specific calibration of in silico predictive models results in reclassification of 28% of missense VUS from ClinGen VCEPs by Shawn Fayer, Malvika Tejura, Abbye McEwen, Lea Starita, Douglas Fowler

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Dynamics of response to asynapsis and meiotic silencing in spermatocytes from Robertsonian translocation carriers. by Anna K Naumova, Shawn Fayer, Jacky Leung, Kingsley A Boateng, R Daniel Camerini-Otero, Teruko Taketo

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P390: Assessing and addressing the burden of VUSs within adult medical genetics practices by Andrew Stergachis, Andrew Folta, Adriana Sedeno-Cortes, Merin Jose, Martha Horike-Pyne, Abbye McEwen, Shawn Fayer, Lea Starita, Marianne Dubard-Gault, Fuki Hisama

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O01: Using multiplexed functional data to reduce the VUS burden in populations underrepresented in genomic medicine by Moez Dawood, Shawn Fayer, Mason Post, Divya Kalra, Karynne Patterson, Eric Venner, Lara Muffley, Douglas Fowler, Alan Rubin, Richard Gibbs, Lea Starita, Carla Daniela Robles-Espinoza, Willow Coyote-Maestas, Irene Gallego Romero

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P008: ClinGen Glucose-6-phosphate dehydrogenase (G6PD) Variant Curation Expert Panel: Addressing the need for genetic variant classification in G6PD deficiency* by Shruthi Mohan, Renee Geck, Shawn Fayer, Roseann Donnelly, Mary Relling, Tom Vulliamy, Kelly Caudle, Amber Waddell, Essence Kendall, Gonzalo Domingo, Angelo Minucci, Benedikt Ley, Cindy Chu, Cyrine Haidar, Howard McLeod, Josef Prchal, Mahmoud Sirdah, Vimla Aggarwal, Weiying Jiang, Emily Kyle, Meredith Weaver, Michelle Whirl-Carrillo, Andrew Stergachis

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