Hammerhead ribozyme-mediated silencing of the mutant fibrillin-1 of tight skin mouse: insight into the functional role of mutant fibrillin-1. by Menon, R, Menon, MR, Shi-Wen, X, Renzoni, E, Bou-Gharios, G, Black, C, Abraham, D

Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1. by Shi-Wen, X, Denton, C, Dashwood, MR, Holmes, A, Bou-Gharios, G, Pearson, J, Black, C, Abraham, D

FUNCTIONAL REGULATION OF FIBROSIS BY CUTL1 ISOFORMS by Ikeda, T, Lindahl, G, Fragiadaki, M, Shi-Wen, X, Ponticos, M, Garcia, P, Denton, C, Bou-Gharios, G, Abraham, D

Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts. by Shi-wen, X, Kennedy, L, Renzoni, E, Bou-Gharios, G, du Bois, R, Black, C, Denton, C, Abraham, D, Leask, A

CTGF Contributes to collagen type I expression in the bleomycin model of lung fibrosis and in human pulmonary fibroblasts by MAPK dependent transcriptional activation by Porticos, M, Holmes, A, Shi-wen, X, Hoyles, R, Bou-Gharios, G, Black, C, Denton, C, Abraham, D, Leask, A, Lindahl, G

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. by Sonnylal, S, Shi-Wen, X, Leoni, P, Naff, K, Van Pelt, C, Nakamura, H, Leask, A, Abraham, D, Bou-Gharios, G, de Crombrugghe, B

Novel transforming growth factor beta transcriptional targets in adult lung fibroblasts indentified by microarray analysis by Renzoni, E, Abraham, D, Shi-Wen, X, Howat, S, Bou-Gharios, G, Wells, A, Veeraraghavan, S, Nicholson, A, Denton, C, Pearson, J, Black, C, Welsh, K, du Bois, R

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile pheno... by Shi-Wen, X, Chen, Y, Denton, C, Eastwood, M, Renzoni, E, Bou-Gharios, G, Pearson, J, Dashwood, M, du Bois, R, Black, C, Leask, A, Abraham, D

Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen. by Ponticos, M, Holmes, A, Shi-wen, X, Leoni, P, Khan, K, Rajkumar, V, Hoyles, R, Bou-Gharios, G, Black, C, Denton, C, Abraham, D, Leask, A, Lindahl, G

Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts. by Shi-Wen, X, Renzoni, E, Kennedy, L, Howat, S, Chen, Y, Pearson, J, Bou-Gharios, G, Dashwood, MR, du Bois, R, Black, C, Denton, C, Abraham, D, Leask, A

Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into path... by Chen, Y, Shi-Wen, X, van Beek, J, Kennedy, L, McLeod, M, Renzoni, E, Bou-Gharios, G, Wilcox-Adelman, S, Goetinck, P, Eastwood, M, Black, C, Abraham, D, Leask, A

Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts. by Renzoni, E, Abraham, D, Howat, S, Shi-Wen, X, Sestini, P, Bou-Gharios, G, Wells, A, Veeraraghavan, S, Nicholson, A, Denton, C, Leask, A, Pearson, J, Black, C, Welsh, K, du Bois, R

CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. by Shi-wen, X, Stanton, L, Kennedy, L, Pala, D, Chen, Y, Howat, S, Renzoni, E, Carter, D, Bou-Gharios, G, Stratton, R, Pearson, J, Beier, F, Lyons, K, Black, C, Abraham, D, Leask, A