Shimon Sakaguchi
is an immunologist and a Distinguished Professor of Osaka University. He is best known for the discovery of regulatory T cells and to describe their role in the immune system. This discovery is used in the treatment of cancer and autoimmune diseases. Provided by Wikipedia
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Control of Germinal Center Responses by T-Follicular Regulatory Cells by James B. Wing, Murat Tekgüç, Shimon Sakaguchi, Shimon Sakaguchi
Published 2018-08-01
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Synovial Tissue Inflammation Mediated by Autoimmune T Cells by Yusuke Takeuchi, Yusuke Takeuchi, Keiji Hirota, Keiji Hirota, Shimon Sakaguchi, Shimon Sakaguchi
Published 2019-08-01
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1036 Treg-specific TCR signaling as a target of cancer immunotherapy by Atsushi Tanaka, Shimon Sakaguchi, Yamin Qian
Published 2023-11-01Article -
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Functional Roles of the IgM Fc Receptor in the Immune System by Hiromi Kubagawa, Kazuhito Honjo, Naganari Ohkura, Shimon Sakaguchi, Andreas Radbruch, Fritz Melchers, Peter K. Jani
Published 2019-05-01
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The ratio of CD8 + lymphocytes to tumor-infiltrating suppressive FOXP3 + effector regulatory T cells is associated with treatment response in invasive breast cancer by Noriko Goda, Shinsuke Sasada, Hideo Shigematsu, Norio Masumoto, Koji Arihiro, Hiroyoshi Nishikawa, Shimon Sakaguchi, Morihito Okada, Takayuki Kadoya
Published 2022-04-01
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Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis by Yusuke Takeuchi, Daiya Ohara, Hitomi Watanabe, Noriko Sakaguchi, Shimon Sakaguchi, Gen Kondoh, Akio Morinobu, Tsuneyo Mimori, Keiji Hirota
Published 2021-09-01
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Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis by Yoshinobu Ikeno, Satoru Seo, Keiko Iwaisako, Tomoaki Yoh, Yuji Nakamoto, Hiroaki Fuji, Kojiro Taura, Hideaki Okajima, Toshimi Kaido, Shimon Sakaguchi, Shinji Uemoto
Published 2018-04-01
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Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes. by Fumitaka Haseda, Akihisa Imagawa, Hiroyoshi Nishikawa, Shinobu Mitsui, Chiharu Tsutsumi, Reiko Fujisawa, Hiroyuki Sano, Yuko Murase-Mishiba, Jungo Terasaki, Shimon Sakaguchi, Toshiaki Hanafusa
Published 2016-01-01
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Essential Roles of SATB1 in Specifying T Lymphocyte Subsets by Kiyokazu Kakugawa, Satoshi Kojo, Hirokazu Tanaka, Wooseok Seo, Takaho A. Endo, Yohko Kitagawa, Sawako Muroi, Mari Tenno, Nighat Yasmin, Yoshinori Kohwi, Shimon Sakaguchi, Terumi Kowhi-Shigematsu, Ichiro Taniuchi
Published 2017-05-01
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HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo. by Yorifumi Satou, Jun-Ichirou Yasunaga, Tiejun Zhao, Mika Yoshida, Paola Miyazato, Ken Takai, Kei Shimizu, Koichi Ohshima, Patrick L Green, Naganari Ohkura, Tomoyuki Yamaguchi, Masahiro Ono, Shimon Sakaguchi, Masao Matsuoka
Published 2011-02-01
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Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4 by Lucia Campos Carrascosa, Matthias Klein, Yohko Kitagawa, Christina Lückel, Federico Marini, Anika König, Anna Guralnik, Hartmann Raifer, Stefanie Hagner-Benes, Diana Rädler, Andreas Böck, Cholho Kang, Michael Lohoff, Holger Garn, Bianca Schaub, Friederike Berberich-Siebelt, Shimon Sakaguchi, Tobias Bopp, Magdalena Huber
Published 2017-05-01
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Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells by Kayo Ikeda, Makoto Kinoshita, Hisako Kayama, Shushi Nagamori, Pornparn Kongpracha, Eiji Umemoto, Ryu Okumura, Takashi Kurakawa, Mari Murakami, Norihisa Mikami, Yasunori Shintani, Satoko Ueno, Ayatoshi Andou, Morihiro Ito, Hideki Tsumura, Koji Yasutomo, Keiichi Ozono, Seiji Takashima, Shimon Sakaguchi, Yoshikatsu Kanai, Kiyoshi Takeda
Published 2017-11-01
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Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma by Yoshiaki Yasumizu, Naganari Ohkura, Hisashi Murata, Makoto Kinoshita, Soichiro Funaki, Satoshi Nojima, Kansuke Kido, Masaharu Kohara, Daisuke Motooka, Daisuke Okuzaki, Shuji Suganami, Eriko Takeuchi, Yamami Nakamura, Yusuke Takeshima, Masaya Arai, Satoru Tada, Meinoshin Okumura, Eiichi Morii, Yasushi Shintani, Shimon Sakaguchi, Tatsusada Okuno, Hideki Mochizuki
Published 2022-07-01
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Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells by Kevin Baßler, Kevin Baßler, Lisa Schmidleithner, Mehrnoush Hadaddzadeh Shakiba, Tarek Elmzzahi, Tarek Elmzzahi, Maren Köhne, Stefan Floess, Rebekka Scholz, Naganari Ohkura, Timothy Sadlon, Kathrin Klee, Anna Neubauer, Shimon Sakaguchi, Simon C. Barry, Jochen Huehn, Lorenzo Bonaguro, Lorenzo Bonaguro, Thomas Ulas, Thomas Ulas, Thomas Ulas, Marc Beyer, Marc Beyer
Published 2023-07-01
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