Manipulating regulatory T cells: is it the key to unlocking effective immunotherapy for pancreatic ductal adenocarcinoma? by Henry Smith, Edward Arbe-Barnes, Enas Abu Shah, Shivan Sivakumar, Shivan Sivakumar

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Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis. by Shivan Sivakumar, Ines de Santiago, Leon Chlon, Florian Markowetz

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HER2 Expression in Gastric Cancer: Rare, Heterogeneous and of No Prognostic Value – Conclusions from 924 Cases of Two Independent Series by Heike Grabsch, Shivan Sivakumar, Sally Gray, Helmut E. Gabbert, Wolfram Müller

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Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (Ther... by Laura Spiers, Michael Gray, Paul Lyon, Shivan Sivakumar, Noor Bekkali, Shaun Scott, Linda Collins, Robert Carlisle, Feng Wu, Mark Middleton, Constantin Coussios

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Nerve Fibers in the Tumor Microenvironment as a Novel Biomarker for Oncological Outcome in Patients Undergoing Surgery for Perihilar Cholangiocarcinoma by Jan Bednarsch, Jakob Kather, Xiuxiang Tan, Shivan Sivakumar, Claudio Cacchi, Georg Wiltberger, Zoltan Czigany, Florian Ulmer, Ulf Peter Neumann, Lara Rosaline Heij

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ToxNav germline genetic testing and PROMinet digital mobile application toxicity monitoring: Results of a prospective single‐center clinical utility study—PRECISE study by Lennard Y. W. Lee, Thomas Starkey, Shivan Sivakumar, Susan Fotheringham, Guy Mozolowski, Vanessa Shearwood, Claire Palles, Philip Camilleri, David Church, Rachel Kerr, David Kerr

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Pseudotime dynamics of T cells in pancreatic ductal adenocarcinoma inform distinct functional states within the regulatory and cytotoxic T cells by Ashwin Jainarayanan, Nithishwer Mouroug-Anand, Edward H. Arbe-Barnes, Adam J. Bush, Rachael Bashford-Rogers, Adam Frampton, Lara Heij, Mark Middleton, Michael L. Dustin, Enas Abu-Shah, Shivan Sivakumar

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Tissue-resident natural killer cells support survival in pancreatic cancer through promotion of cDC1-CD8 T activity by Simei Go, Constantinos Demetriou, Giampiero Valenzano, Sophie Hughes, Simone Lanfredini, Helen Ferry, Edward Arbe-Barnes, Shivan Sivakumar, Rachel Bashford-Rogers, Mark R Middleton, Somnath Mukherjee, Jennifer Morton, Keaton Jones, Eric O Neill

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Expression of Checkpoint Molecules in the Tumor Microenvironment of Intrahepatic Cholangiocarcinoma: Implications for Immune Checkpoint Blockade Therapy by Lara Heij, Jan Bednarsch, Xiuxiang Tan, Mika Rosin, Simone Appinger, Konrad Reichel, Dana Pecina, Michail Doukas, Ronald M. van Dam, Juan Garcia Vallejo, Florian Ulmer, Sven Lang, Tom Luedde, Flavio G. Rocha, Shivan Sivakumar, Ulf Peter Neumann

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Evaluation of pre-analytical factors affecting plasma DNA analysis by Havell Markus, Tania Contente-Cuomo, Maria Farooq, Winnie S. Liang, Mitesh J. Borad, Shivan Sivakumar, Simon Gollins, Nhan L. Tran, Harshil D. Dhruv, Michael E. Berens, Alan Bryce, Aleksandar Sekulic, Antoni Ribas, Jeffrey M. Trent, Patricia M. LoRusso, Muhammed Murtaza

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Unlocking the diagnostic power of plasma extracellular vesicle miR-200 family in pancreatic ductal adenocarcinoma by Daniel S.K. Liu, Jisce R. Puik, Bhavik Y. Patel, Morten T. Venø, Mahrou Vahabi, Mireia Mato Prado, Jason P. Webber, Eleanor Rees, Flora M. Upton, Kate Bennett, Catherine Blaker, Benoit Immordino, Annalisa Comandatore, Luca Morelli, Shivan Sivakumar, Rutger-Jan Swijnenburg, Marc G. Besselink, Long R. Jiao, Geert Kazemier, Elisa Giovannetti, Jonathan Krell, Adam E. Frampton

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A bile-based microRNA signature for differentiating malignant from benign pancreaticobiliary disease by Mireia Mato Prado, Jisce R. Puik, Leandro Castellano, Elena López-Jiménez, Daniel S. K. Liu, Laura L. Meijer, Tessa Y. S. Le Large, Eleanor Rees, Niccola Funel, Shivan Sivakumar, Stephen P. Pereira, Geert Kazemier, Babs M. Zonderhuis, Joris I. Erdmann, Rutger-Jan Swijnenburg, Andrea Frilling, Long R. Jiao, Justin Stebbing, Elisa Giovannetti, Jonathan Krell, Adam E. Frampton

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Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms by Shivan Sivakumar, Ashwin Jainarayanan, Edward Arbe-Barnes, Piyush Kumar Sharma, Maire Ni Leathlobhair, Sakina Amin, David J. Reiss, Lara Heij, Samarth Hegde, Assaf Magen, Felicia Tucci, Bo Sun, Shihong Wu, Nithishwer Mouroug Anand, Hubert Slawinski, Santiago Revale, Isar Nassiri, Jonathon Webber, Gerard D. Hoeltzel, Adam E. Frampton, Georg Wiltberger, Ulf Neumann, Philip Charlton, Laura Spiers, Tim Elliott, Maria Wang, Suzana Couto, Thomas Lila, Pallavur V. Sivakumar, Alexander V. Ratushny, Mark R. Middleton, Dimitra Peppa, Benjamin Fairfax, Miriam Merad, Michael L. Dustin, Enas Abu-Shah, Rachael Bashford-Rogers

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