Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing by Xiaomin Wang, Yanhui Liang, Jianping Zhao, Yuan Li, Shixue Gou, Min Zheng, Juanjuan Zhou, Quanjun Zhang, Jidong Mi, Liangxue Lai

Get full text

Exonuclease editor promotes precision of gene editing in mammalian cells by Hui Shi, Lei Li, Shuangshuang Mu, Shixue Gou, Xiaoyi Liu, Fangbing Chen, Menglong Chen, Qin Jin, Liangxue Lai, Kepin Wang

Get full text

Author Correction: Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing by Xiaomin Wang, Yanhui Liang, Jianping Zhao, Yuan Li, Shixue Gou, Min Zheng, Juanjuan Zhou, Quanjun Zhang, Jidong Mi, Liangxue Lai

Get full text

Enhancing prime editor flexibility with coiled-coil heterodimers by Shuangshuang Mu, Huangyao Chen, Qianru Li, Shixue Gou, Xiaoyi Liu, Junwei Wang, Wei Zheng, Menglong Chen, Qin Jin, Liangxue Lai, Kepin Wang, Hui Shi

Get full text

In vivo evaluation of guide-free Cas9-induced safety risks in a pig model by Weikai Ge, Shixue Gou, Xiaozhu Zhao, Qin Jin, Zhenpeng Zhuang, Yu Zhao, Yanhui Liang, Zhen Ouyang, Xiaoyi Liu, Fangbing Chen, Hui Shi, Haizhao Yan, Han Wu, Liangxue Lai, Kepin Wang

Get full text

Evolved cytidine and adenine base editors with high precision and minimized off-target activity by a continuous directed evolution system in mammalian cells by Na Zhao, Jian Zhou, Tianfu Tao, Qi Wang, Jie Tang, Dengluan Li, Shixue Gou, Zhihong Guan, Joshua Seun Olajide, Jiejing Lin, Shuo Wang, Xiaoping Li, Jiankui Zhou, Zongliang Gao, Gang Wang

Get full text

Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos by Weikai Ge, Xiaozhu Zhao, Shixue Gou, Qin Jin, Fangbing Chen, Zhen Ouyang, Chengdan Lai, Tao Cui, Baoyi Mai, Sijia Lu, Kexin Zhong, Yanhui Liang, Tao Chen, Han Wu, Nan Li, Yinghua Ye, Liangxue Lai, Kepin Wang

Get full text

Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation by Qin Jin, Xiaoyi Liu, Zhenpeng Zhuang, Jiayuan Huang, Shixue Gou, Hui Shi, Yu Zhao, Zhen Ouyang, Zhaoming Liu, Lei Li, Junjie Mao, Weikai Ge, Fangbing Chen, Manya Yu, Yezhi Guan, Yinghua Ye, Chengcheng Tang, Ren Huang, Kepin Wang, Liangxue Lai

Get full text

In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers by Menglong Chen, Hui Shi, Shixue Gou, Xiaomin Wang, Lei Li, Qin Jin, Han Wu, Huili Zhang, Yaqin Li, Liang Wang, Huan Li, Jinfu Lin, Wenjing Guo, Zhiwu Jiang, Xiaoyu Yang, Anding Xu, Yuling Zhu, Cheng Zhang, Liangxue Lai, Xiaoping Li

Get full text

ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems by Jingke Xie, Xingyun Huang, Xia Wang, Shixue Gou, Yanhui Liang, Fangbing Chen, Nan Li, Zhen Ouyang, Quanjun Zhang, Weikai Ge, Qin Jin, Hui Shi, Zhenpeng Zhuang, Xiaozhu Zhao, Meng Lian, Jiaowei Wang, Yinghua Ye, Longquan Quan, Han Wu, Kepin Wang, Liangxue Lai

Get full text

Efficient base editing for multiple genes and loci in pigs using base editors by Jingke Xie, Weikai Ge, Nan Li, Qishuai Liu, Fangbing Chen, Xiaoyu Yang, Xingyun Huang, Zhen Ouyang, Quanjun Zhang, Yu Zhao, Zhaoming Liu, Shixue Gou, Han Wu, Chengdan Lai, Nana Fan, Qin Jin, Hui Shi, Yanhui Liang, Ting Lan, Longquan Quan, Xiaoping Li, Kepin Wang, Liangxue Lai

Get full text

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors by Fangbing Chen, Meng Lian, Bingxiu Ma, Shixue Gou, Xian Luo, Kaiming Yang, Hui Shi, Jingke Xie, Weika Ge, Zhen Ouyang, Chengdan Lai, Nan Li, Quanjun Zhang, Qin Jin, Yanhui Liang, Tao Chen, Jiaowei Wang, Xiaozhu Zhao, Lei Li, Manya Yu, Yinghua Ye, Kepin Wang, Han Wu, Liangxue Lai

Get full text

Human induced-T-to-natural killer cells have potent anti-tumour activities by Zhiwu Jiang, Le Qin, Yuou Tang, Rui Liao, Jingxuan Shi, Bingjia He, Shanglin Li, Diwei Zheng, Yuanbin Cui, Qiting Wu, Youguo Long, Yao Yao, Zhihui Wei, Qilan Hong, Yi Wu, Yuanbang Mai, Shixue Gou, Xiaoping Li, Robert Weinkove, Sam Norton, Wei Luo, Weineng Feng, Hongsheng Zhou, Qifa Liu, Jiekai Chen, Liangxue Lai, Xinwen Chen, Duanqing Pei, Thomas Graf, Xingguo Liu, Yangqiu Li, Pentao Liu, Zhenfeng Zhang, Peng Li

Get full text