Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase. by Ren, J, Milton, J, Weaver, K, Short, SA, Stuart, D, Stammers, D

Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors. by Ren, J, Nichols, C, Chamberlain, P, Weaver, K, Short, SA, Stammers, D

Crystal structures of HIV-1 reverse transcriptase mutated at codons 100, 106 and 108 show nevirapine resistance is mediated via perturbation of interactions with Tyr181 or Tyr188 by Stammers, D, Ren, J, Nichols, C, Chamberlain, P, Weaver, K, Short, SA, Stuart, D

Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr1... by Ren, J, Nichols, C, Chamberlain, P, Weaver, K, Short, SA, Chan, J, Kleim, J, Stammers, D

Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138. by Ren, J, Nichols, C, Stamp, A, Chamberlain, P, Ferris, R, Weaver, K, Short, SA, Stammers, D

Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor. by Romines, K, Freeman, G, Schaller, LT, Cowan, JR, Gonzales, S, Tidwell, J, Andrews, C, Stammers, D, Hazen, R, Ferris, R, Short, SA, Chan, J, Boone, L

Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor. by Romines, K, Freeman, G, Schaller, LT, Cowan, JR, Gonzales, S, Tidwell, J, Andrews, C, Stammers, D, Hazen, R, Ferris, R, Short, SA, Chan, J, Boone, L

Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. by Ren, J, Chamberlain, P, Stamp, A, Short, SA, Weaver, K, Romines, K, Hazen, R, Freeman, A, Ferris, R, Andrews, C, Boone, L, Chan, J, Stammers, D

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2. by Freeman, G, Andrews, C, Hopkins, A, Lowell, G, Schaller, LT, Cowan, JR, Gonzales, S, Koszalka, G, Hazen, R, Boone, L, Ferris, R, Creech, K, Roberts, G, Short, SA, Weaver, K, Reynolds, D, Milton, J, Ren, J, Stuart, D, Stammers, D, Chan, J

2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. by Chan, J, Hong, J, Hunter, R, Orr, G, Cowan, JR, Sherman, D, Sparks, S, Reitter, B, Andrews, C, Hazen, R, St Clair, M, Boone, L, Ferris, R, Creech, K, Roberts, G, Short, SA, Weaver, K, Ott, R, Ren, J, Hopkins, A, Stuart, D, Stammers, D